Combating poverty is a global issue. In the past, anti-poverty strategy heavily rely on in-kind and in-cash social assistance, until microfinance model had proved remarkable saving outcomes, and then its ideology had swept the world. After the concept of Grameen Bank is widely recognized by Taiwanese, fostering small business and fostering self-reliance to create a cycle of sustainability pave an innovative thinking for social assistance models, and modify the conventional social welfare paradigm. The aforementioned factor thus brings about the origin of Taiwan’s Microfinance Program. This research interviewed the program stakeholders to conclude strategies to improve cost-effectiveness, as the program performances, judged by most program stakeholders, remained unsatisfied for a while. The research consistently addresses the aforementioned issues in terms of bank design, borrower characteristics, and bank supportive services; then, the research paper draws a conclusion and recommendations to improve the program performance.