As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

Nutrigenomics studies the genome-wide influence of nutrients to understand the association between nutrition and human health. Studies in animal models and humans have demonstrated that dietary n-3 polyunsaturated fatty acids (PUFA) from fish oil may be beneficial in inflammatory bowel diseases (IBD). This thesis aimed to test the hypothesis that dietary n-3 PUFA eicosapentaenoic acid (EPA) reduced and n-6 PUFA arachidonic acid (AA) increased colitis in the interleukin- 10 gene-deficient (Il10–/–) mouse model of IBD, and that these PUFA altered the intestinal bacteria community during colitis development using genome-wide expression and bacterial profiling. Using a combined transcriptomic and proteomic approach, the time-course study defined the onset and progression of colitis in Il10–/– mice. Histopathology, transcript and protein changes before and after colitis onset involved in innate and adaptive immune responses suggested delayed remodelling processes in colitic Il10–/– mice and 11 weeks of age as suitable time point to study the effects of dietary PUFA on colitis development. Comparing the transcriptome and proteome profiles associated with colon inflammation of mice fed with the AIN-76A or oleic acid (OA) diet showed that OA was an appropriate control for unsaturated fatty acids in multi-omic studies. The PUFA intervention study indicated that dietary EPA-induced lipid oxidation might have a potential anti-inflammatory effect on inflamed colon tissue partially mediated through activation of peroxisome proliferator-activated receptor alpha (PPARα). Unexpectedly, dietary AA decreased the expression of inflammatory and stress colonic genes in Il10–/– mice. Altered intestinal bacteria community observed in Il10–/– mice before and after colitis onset was associated with the lack of IL10 protein led to changes in intestinal metabolic and signalling processes. Interestingly, dietary EPA and AA seemed to change intestinal bacteria profiles during colitis development. The role of PPARα in the colon was further examined in a concluding study which identified vanin1 as a likely new PPARα-target gene which may also be involved in lipid metabolism. These findings using a state-of-the-art approach combining transcriptomics, proteomics and physiology provide a basis for future research on molecular mechanisms underlying the effects of dietary PUFA, and might contribute to the development of fortified foods that improve intestinal health and wellness.

Anthocyanins (ACNs), which are responsible for the red and blue colours displayed by many vegetables and fruits (particularly berries), belong to secondary plant metabolites, and are a component of our daily diet. There is an increasing interest on their biological activities as they are claimed to enhance health by protecting against some chronic diseases. However, before ACNs can perform health-promoting effects in vivo, they must first be sufficiently absorbed, distributed within the human body, and reach target tissues in adequate concentrations. To date, all studies investigating ACN absorption and metabolism came to the conclusion that their bioavailability is extremely low. To benefit from the proposed health effects of ACNs, their bioavailability, including absorption, metabolism, and excretion must first be understood. The main objective of this thesis was to provide further knowledge on ACN absorption, including the absorption site and mechanism, and the influence of food and other flavonoids on ACN absorption, as well as the investigation of their antioxidant effects in vivo. In vitro experiments using Ussing chambers showed that a strong absorption of ACNs occurred from the jejunum in mice. This was supported with a further in vivo study, where the major absorption site for ACNs may be the jejunum in rats. The limitation of ACN absorption to mainly one part of the intestine suggested the participation of a particular transport mechanism. In a further Ussing chamber study it was shown that flavonols, another common flavonoid group present in many fruits and vegetables, strongly inhibit ACN absorption, indicating a specific transport mechanism, with preference for other flavonoid compounds. Further in vivo studies have shown that the simultaneous ingestion of food components, such as breakfast cereals, resulted in a delayed absorption profile in two animal species. However, the additional food did not influence the antioxidant effect of ACNs. During a human intervention study, several measures of oxidative stress improved, but this improvement occurred equally in the treatments and placebo control, and may have resulted from changes in lifestyle. The results of these studies aid to understand details of ACN absorption and help to formulate future recommendations for ACN intake with increased bioavailability in humans.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.

As the population ages it is increasingly important to understand the factors influencing dietary habits of older people. Social, biological and psychological factors influence food intake and affect nutrition risk among older people living in the community. The purpose of this study was to identify food-related behaviours that place older people at nutrition risk and to evaluate older peoples’ perceptions and experiences of various nutrition support options. Fifty-one community living people aged between 80 and 85 years were recruited in North Shore City. Food-related behaviours were explored with the use of three quantitative tools. Practitioner Assessment of Network Type (PANT) was used to evaluate social networks. Elderly Assessment System (EASY-Care) was used to evaluate physical and mental wellbeing. Seniors in the Community: Risk Evaluation for Eating and Nutrition Version II (SCREEN II) assessed nutrition risk. Five people participated in a qualitative interview about nutrition support they had received. A third of the participants (31 percent) were found to be at nutrition risk. Twothirds (67 percent) showed some evidence of disability and needed assistance with everyday tasks. Nearly half (47 percent) of these older people had supportive social networks including close relationships with local family, friends and neighbours. There was an inverse linear relationship between participants’ self-rated health and nutrition risk (p<.001). Those who perceived their health to be fair or poor were more likely to be at nutrition risk. The importance of social contact, a sense of gratitude, ‘getting a meal’, and ‘meeting the need’ were common themes that emerged from interviews with participants who received nutrition support. These findings indicate that nutrition risk may be prevalent among community living older people in New Zealand. Strategies and initiatives are needed to encourage independent living and to help older people with the procurement, preparation, cooking and sharing of enjoyable meals.