This study aims to identify the quality of knowledge management practices and success factors of non-governmental organisations in Malawi, and their influence on the knowledge management process. A questionnaire-based survey is used to establish the knowledge management practices being implemented and the extent to which they are being followed through on. A statistical-based analysis enabled the researcher to determine the influence of these practices on knowledge management processes. Results suggest an unbalanced pursuit of knowledge management practices in Malawian non-governmental organisations, which are oriented towards the knowledge generation process but fall short in knowledge application activities. This study contributes to strategy formulation and decision making in respect of adopting and investing in knowledge management initiatives in the non-profit sector. More importantly, it joins the debate on identification of appropriate practices which effectively address organisational needs. Data is limited to non-governmental organisations in Malawi; therefore, findings may be tied to a specific geographical location / School of Computing / M.Sc. (Computing)