Near field imaging using microwaves in medical applications is of great current interest for its capability and accuracy in identifying features of interest, in comparison with other known screening tools. Many imaging methods have been developed over the past two decades showing the potential of microwave imaging in medical applications such as early breast cancer detection, analysis of cardiac tissues, soft tissues and bones. Microwave imaging uses non-ionizing ultra wideband (UWB) electromagnetic signals and utilises tissue-dependent dielectric contrast to reconstruct signals and images using radar-based or tomographic imaging techniques. Microwave imaging offers low health risk, low operational cost, ease of use and user-friendliness. This study documents microwave imaging experiments for early breast cancer detection and bone fracture detection using radar approach. An actively tuned UWB patch antenna and a UWB Vivaldi antenna are designed and utilised as sensing elements in the aforementioned applications. Both UWB antennas were developed over a range of frequency spectrum, and then characteristics were tested against their ability for microwave imaging applications by reconstructing the 3D Inversion Algorithm. An experiment was conducted using patch antenna to test the detection of variable sizes of cancer tissues based on a simple phantom consisting of a plastic container with a low dielectric material emulating fatty tissue and high dielectric constant object emulating a tumour, is scanned between 4 to 8 GHz with the patch antenna. A 2-D image of the tumour is constructed using the reflected signal response to visualize the location and size of the tumour. A Vivaldi antenna is designed covering 3.1 to 10.6 GHz. The antenna is tested via simulation for detecting bone fractures of various sizes and 2-D images are generated using reflected pulses to show the size of fracture. The Vivaldi antenna is optimised for early breast cancer detection and detailed simulated study is carried out using different breast phantoms and tumour sizes. Simulations are backed with the experimental investigation with the test setup used for patch antenna. Generated images for simulations and experimental investigation show good agreement, and show the presence of tumour with good location accuracy. Measurements indicate that both prototype microwave sensors are good candidates for tested imaging applications.