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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

Two-state models of heterogeneity on tree-like topologies

Handford, Thomas Phillip January 2014 (has links)
No description available.

Methods to detect cystosine modifications in mammalian DNA

Booth, Michael John January 2014 (has links)
No description available.

Design, synthesis and biological evaluation of a selective inhibitor of HSET that targets cancer cells with supernumerary centrosomes

Watts, Ciorsdaidh Ann January 2014 (has links)
No description available.

Target-based and phenotypic approaches towards novel inhibitors of DNA repair and mitosis

Laraia, Luca January 2014 (has links)
No description available.

Quantitative single-molecule imaging methods for studies of the spatiotemporal organisation of cell surface receptors

Weimann, Laura January 2014 (has links)
No description available.

A density functional theory study on a manganese dioxide-water interface : acidity constants and redox potentials

Kattirtzi, John Andrew January 2014 (has links)
No description available.

Small molecule approaches targeting the Polo-box domain of Polo-like kinase 1

Stokes, Jamie Edward January 2014 (has links)
No description available.

Supramolecular self-assembly of noble metal nanoparticles via cucurbit(8)uril ternary complex formation

Jones, Samuel Thomas January 2014 (has links)
No description available.

Advanced characterisation of catalytic materials using synchrotron radiation techniques

Daley, T. E. January 2015 (has links)
Heterogeneous catalysis is a large and important field of research, and is especially of interest to the project sponsors Johnson Matthey (JM). This EngD project focused on studying catalytic materials of interest to JM in order to investigate the metal support interaction and determine the effects of various reaction conditions. The key techniques used in this work are synchrotron radiation based, such as X-ray absorption spectroscopy (XAS), X-ray diffraction (XRD) as well as combinations of techniques. A variety of catalytic materials have been investigated using synchrotron X-ray techniques and conventional laboratory analytical techniques. Understanding these processes will allow for the tailoring of catalyst design and modification of support materials that will lead to improved and more efficient catalytic materials in the future. Supported platinum group metals were studied during reduction using in situ XAS. The materials were prepared through sequential deposition on an alumina support of first the platinum group metal then a ceria layer; this additional layer of ceria was deposited to cover the metal particles, limiting movement and gas transfer processes. The effect of the MSI on the reduction of Pd nanoparticles supported on a variety of inorganic materials in order to determine the structure of metal particles was also explored using in situ XAS. A combination of the LIII- and K-edge analysis was utilised to provide a better understanding of metal support interaction and the changes in the electronic structure for supported Pd nanoparticles. Other materials investigated include zinc oxide nanoparticles, which are important for a variety of applications due to their semi-conductor properties. Additionally AuCu bimetallic clusters were investigated in situ during reduction, calcination and during the catalytic oxidation of propene. The use of XAS allowed for the probing of the extent of the metal alloying and the effect on the propene catalysis.

The modification of biotin analogues to function as multipurpose labelling tools

Sehmi, Inderpal Kaur January 2014 (has links)
This project has focused on establishing a specific multipurpose labelling system via the modification of D-( + )-biotin in use with (strept)avidin proteins for purification and isolation. Two biotin analogues; 2-azidobiotin and 2-propargylbiotin, have been synthesised, introducing an alkyne and azide group at the 2 position of the valeryl side chain of biotin respectively. Isothermal titration calorimetry studies showed that the biotin analogues had a reduced affinity (Kd= 1V10-9 M) for strept(avidin) proteins, when compared to biotin (Kd= ~10-15 M).

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