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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Endovascular photodynamic therapy for preventing post-angioplasty and in-stent restenosis

Pai, Mahesh Laxman January 2005 (has links)
Cardiovascular disease is the commonest cause of death in the western world and atherosclerosis is the commonest cause of cardiovascular disease. It is characterised by the deposition of intra-luminal plaque leading to arterial stenosis. Balloon angioplasty offers a minimally invasive method of dilating peripheral and coronary arterial stenosis. The results of angioplasty are improved by stenting. However, a significant percentage of these patients have restenosis of their arteries with clinical and resource implications. Restenosis is caused by neointimal hyperplasia (NIH) and negative remodelling the combined effects of which result in vessel re-narrowing. It has previously been shown in animal models that photodynamic therapy (PDT) reduces the restenosis when used as an adjuvant to angioplasty. PDT involves the interaction of light at a particular wavelength with a pre-administered photosensitive agent to produce cell death by apoptosis in the presence of oxygen. The aims of this thesis are two fold. 1. to optimise the effects of PDT in preventing in-stent restenosis 2. to conduct a randomised controlled trial to show the clinical benefits of PDT in preventing post-angioplasty restenosis.
2

Development of recombinant adeno-associated virus and second generation adenovirus vectors for the gene transfer of human apolipoprotein E (ApoE) in the APOE deficient mouse

Harris, Julian David January 2005 (has links)
No description available.
3

The role of matrix metalloproteinases in an animal model of atherosclerotic plaque rupture

Johnson, Jason Lee January 2005 (has links)
No description available.
4

An investigation of gene and protein expression in carotid plaques

Elasbali, Abdulbaset January 2006 (has links)
No description available.
5

Mechanisms involved in the role of chylomicron remnants in the induction of lipid accumulation in THP-1 macrophages

Moore, Elizabeth Helen January 2005 (has links)
No description available.
6

Endothelial dysfunction in atherosclerosis

Kharbanda, Rajesh Kumar January 2003 (has links)
No description available.
7

Mechanism of arterial neointima formation : study of the effects of angiogenic factors in vivo

Khurana, Rohit January 2004 (has links)
No description available.
8

The identification of novel genes involved in atherosclerotic plaque instability using a whole-transcriptome approach

Papaspyridonos, Marianna January 2005 (has links)
No description available.
9

A study of the impacts of expression and genetic variation of matrix metalloproteinases on atherosclerosis

Morgan, Angharad R. January 2004 (has links)
No description available.
10

A study of the relationships between ABCA I gene polymorphisms, plasma lipid levels and risk of atherosclerosis

Bogari, Neda Mustafa January 2007 (has links)
No description available.

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