Thesis (MA (Hons))--University of South Australia, 2000

Thesis (MA)--University of South Australia, 1998

Zugl.: Bremen, Univ., Diss., 2006

Thesis (Ph. D.)--University of Hong Kong, 1997. / Includes bibliographical references (leaf 635-652).

Universiẗat, Diss., 2001--Giessen.

No description available.

The microsomal ethanol oxidizing system (MEOS) is involved in metabolism of alcohol in the liver, the major component of MEOS is cytochrome P4502E1 (CYP2E1). CYP2E1 gene polymorphisms that alter its functions may be associated with alcohol susceptibility in individual. A RsaI/PstI restriction fragment length polymorphism (RFLP) has been reported in the 5¡¦-flanking region of CYP2E1 gene. The rare mutant allele (c2 allele) that lacks the Rsa I restriction site, but can cut with Pst I has been found to be associated with higher transcriptional activity, mRNA expression, protein levels and enzyme activity than the commom wild type-c1 allele. CYP2E1-dependent oxidative stress on the pathogenesis of alcohol-induced liver injury. The recent epidemiological studies have point out that there are a high prevalence of alcohol consumption in aborigines of Southern taiwan. Dr.Bosron presented an drinks wine the behavior receives the environment and the genetic factor influence, this kind of difference also receives the racial influence to be really big. This study focus on the aborigines with high alcohol drinks rate to examine the possible effect on drinks habit and gene polymorphism of CYP2E1 RsaI/PstI to blood biochemicial index. The experimental result found that male aborigines drinker in blood pressure, triglyceride, HDL cholesterol, uric acid and AST value more than male aborigines non-drinker. However the values are in T.cholesterol, LDL cholesterol, creatinine less than non-drinker. The female aborigines drinker in blood pressure, HDL cholesterol, uric acid, creatinine and AST value more than female aborigines non-drinker. However the values are in T.cholesterol and LDL cholesterol less than non-drinker. Nevertheless, male aborigines drinker and female aborigines non-drinker did not achieved diversity of statistical in function of CYP2E1 gene polymorphism to biochemical index. Male aborigines non-drinkers have c1/c2+c2/c2 in CYP2E1 gene polymorphism compare to c1/c1 also have higher WHR (0.93¡Ó0.05 vs. 0.90¡Ó0.06, p = 0.035) and ALT (30.0¡Ó22.0 IU/L vs. 21.5¡Ó11.0 IU/L , p = 0.012). To summary, male aborigines who have c2 allele in CYP2E1 gene polymorphism may relate to obese and Liver dysfuction.

Research Doctorate - Doctor of Philosophy (PhD) / Since the 1970’s, there has been a growing impetus in Australian education to include Aboriginal issues across the full range of educational settings, from pre-school to tertiary levels. In practice, the provision of an Aboriginal perspective has often lead to socio-cultural constructions of Aboriginal people that tend to reflect, rather than contest, hegemonic understandings of Aboriginal people and culture. In doing this some fundamental misconceptions are continuing to have currency within mainstream Australia, becoming more entrenched due to the ascribed legitimacy of the educational institutions. The discipline of sociology has recently self-identified an absence in its scholarship related to provision of comment on Aboriginal issues. The challenge for the future is to find meaningful alternatives that allow for the diversity of Aboriginal cultures and histories to be interpreted through a multiplicity of cultural subjectivities. Given the diversity of both Aboriginal cultures and the student cohorts examining them, an essentialising curriculum based on the inclusion of Aboriginal content is ultimately unhelpful. Rather, the development of critical pedagogies actively seeking a localised praxis is of far greater utility. This thesis considers the author’s pedagogical approach to teaching Aboriginal perspectives within the mainstream discipline of sociology at a regional university in New South Wales, Australia. Methodologically, the thesis is framed on a syncretic model between the Western mode of auto-ethnography and the Indigenous narrative tribalography. It includes a deeply reflexive component that aims to illustrate the way the Aboriginal lived experience can inform teaching, as well as a more standard textual engagement with academic literature and debate. Specific focus will be applied to consideration of The Dreaming as a foundational Aboriginal philosophy.

Thesis (MA (AborStud))--University of South Australia, 1994

Thesis (M.A.)--University of Hong Kong, 1995. / Includes bibliographical references (leaf 130-136). Also available in print.