Background/Objectives: The first objective of this study is to assess the relationship between cigarette access and smoking behavior in 15-17 year old students. The second objective of this study is to assess the relationship between media and smoking behavior in those students. The third objective of this study is to observe whether the smoking rate will increase if subjects have both access and exposure to the tobacco product. I propose to use the youth survey data to test the impact of exposure to smoking-related media messages and the difficulty of acquiring tobacco products. I hypothesize that there is positive relationship among youth access to tobacco products, exposure to tobacco ads/promotions on social networking sites and active smoking. Methods: I examined National Youth Tobacco Survey data from 2014 and a total number of 1293 subjects as a secondary analysis. Results: The students with one or more than one method of accessing tobacco had higher odds compared to students with no access (OR = 70.12; 95% CI: 47.71–103.07; p < 0.0001 for only one method; OR = 240.22; 95% CI: 160.25–360.09; p < 0.0001 for more than one method). Moreover, the association between exposure to tobacco ads via internet, newspaper, point stores and movies/TV and smoking behavior was significant at both moderate and heavy exposure levels (OR = 1.44; 95% CI: 1.08–1.92; p = 0.014 for moderate exposure group; OR = 1.82; 95% CI: 1.26–2.62; p = 0.002 for heavy exposure group). The multivariable model, which shows the effect of the combination of these two factors, it states access to tobacco products was significantly positively associated with an increased smoking rate (OR = 69.06; 95% CI: 47.03-101.40; p < 0.001 for only one access group; OR = 241.78; 95% CI: 160.49–364.22; p < 0.001 for more than 1 access group). However, the severity of media exposure was not significantly associated with the increased odds of cigarette smoking among adolescents (OR = 1.14; 95% CI: 0.80-1.62; p = 0.470 for moderate exposure group; OR = 1.39; 95% CI: 0.81–2.40; p = 0.227 for heavy exposure group). Conclusion: I provided further evidence that exposure to tobacco messages and have access to tobacco products can increase the smoking rates among youth. These findings could be a result of better diagnosis and reporting, but the increase may also be due to other risk factors in the population. These findings may have implications for further and more aggressive counseling for teenagers. These effects should be further explored in a larger population of adolescents. Intervention methods should be designed to help the public understand the benefits of reducing adolescent’s exposures to tobacco smoke. / Epidemiology