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HIV directed ribozymes in vitro and in cell cultureCrisell, P. D. January 1992 (has links)
No description available.
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Cytokine regulation of HIV-1 in macrophages and lymphocytes in vitroMontaner, Luis J. January 1995 (has links)
No description available.
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Simian immunodeficiency virus : specific cytotoxic T cell responses in cynomolgus macaques; implications for vaccine developmentGallimore, Awen M. January 1994 (has links)
No description available.
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Structure-based design of novel inhibitors of HIV-1 reverse transcriptaseHopkins, Andrew Lee January 1998 (has links)
No description available.
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The biological safety and efficacy of cochlear implantation in young children : an evaluation in an animal modelBurton, Martin James January 1994 (has links)
No description available.
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The within host dynamics of HIV infectionFrost, Simon David William January 1995 (has links)
No description available.
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Characterisation of intestinal mucosal abnormality associated with HIV infectionMcGowan, Ian Michael January 1994 (has links)
No description available.
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The construction of masculinity and risk-taking behaviour among adolescent boys in seven schools in the Western Cape.Jeftha, Alethea January 2006 (has links)
The term, risk-taking, has often been used to describe some of the behaviours and their associated negative outcomes occurring during adloscence. Statistics have shown that South Africa has one of the highest rates of HIV/AIDS infection in the world, with most infections occurring during adolescence. The central aim in this study was to explore the relationship between current constructions of masculinity and risk-taking behaviours among a group of young South African men. It was an exploratory study, focused on exploring how young men construct their masculinities, and how this intersects with or impacts on adolescent male risk-taking behaviours. A key conclusion drawn at the end of this project was that some traditional notions of manhood still held sway, and these tied in strongly with how these participants constructed their masculinity.
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Gender and age differences in condom use patterns among youth in the Eastern Cape, South Africa: a descriptive and analytical study.Jama, P. Nwabisa January 2006 (has links)
South Africa is estimated to have one of the highest epidemics of HIV infection. Recent youth studies have found that youth aged 15-24 years are increasingly becoming vulnerable to HIV. Condom use is promoted as one of the key HIV prevention methods in South Africa. Face-to-face structured questionnaire interviews were conducted with a volunteer sample of rural active women and men aged 15-26 years living in 70 villages in the Eastern Cape Province. Most of the participants were recruited in schools.
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Review of patient follow up mechanisms in the two Ekurhuleni metropolitan hospitals providing antiretroviral treatmentNcholo, Emmanuel Kgotso 10 March 2010 (has links)
MPH, Faculty of Health Sciences, University of the Witwatersrand, 2009. / Introduction
Patient retention and loss to follow-up in the antiretroviral programmes in South
Africa and indeed the world is important as failures to reduce these lead to higher
drug resistances and treatment failures. In the light of the few drugs available to treat
HIV and AIDS it is imperative that patients lost to follow-up be traced and brought
back into the programme. The objectives of the study were to quantify the number of
patients enrolled in the programme between 01st June 2004 and 31st December 2004;
determine the demographic profile of enrolled patients with regard to age; sex;
education; employment and area of residence; to determine compliance and defaulter
rates at every monthly appointment up to 6 months of follow-up and to describe
follow-up systems in place for tracking patients on ARVs; identifying those who fail
to comply with scheduled appointments; and ensuring complianceand finally to
identify challenges faced by the hospitals in tracking patients on ARV therapy.
Material and Methods
The two hospital chosen were the first public hospitals to rollout antiretroviral
treatment in Ekurhuleni in 2004. This was a descriptive study involving review of
health facility records and primary data collection through key informant interviews at
two district hospitals in Ekurhuleni. The study reviewed mechanisms employed by the
two hospitals in tracking those patients who started on the programme during the first
six months of the ARV programme (June 2004 to December 2004).
Results
The two hospitals had after six months of starting with the rollout a combined number
of 378 patients on treatment. Far East Rand Hospital (FERH) had registered 208
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patients and Natalspruit (NSH) had 170 patients on their register. Most of the patients
started on treatment were from Townships (82%), and 81% of all patients started on
treatment were unemployed. The male(33.7%) to female (62.7) ratio was 1:2. Even
though on average 90% of patients at both hospitals kept their first six appointment,
defaulter rates at FERH was 23,2% and NSH was sitting at 33,1%.
Discussion
Our results show tha the two hospitals fall short on achieving the requierements by
the Departmentof Health’s HIV plan that states under Priority Area 2, point 6.2, that
accredited facilities must have the capacity to increase the retention of children and
adults on ART – actively trace people on ART who are more than a month late for
clinic/pharmacy appointment. The hospitals do not have proper tracking mechanisms
in place, they lack important resources like transport, telephones and get wrong
addresses. Based on the evidence we have gathered the hospitals’ defaulter rates and
loss to follow-up are a concern but they are also not far off when compared to other
places and countries whose defaulter rates are 20% on average.
Conclusion and Recommendation
Retention of patients in the programmes is an essential health imperative. It is
therefore necessary that we make the following improvements to our hospital
programmes: Make resources like telephone and transport available to healthcare
workers; employ a dedicated team of workers doing only patient tracing and followup;
invest in technology that would alert health care workers immediately a patient
misses an appointment and finally educate the patients themselves of the importance
of adherence to treatment and follow-up.
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