Thesis (Ph. D., Education)--University of Idaho, May 2008. / Major professor: Sharon K. Stoll. Includes bibliographical references (leaves 150-156). Also available online (PDF file) by subscription or by purchasing the individual file.

Thesis (Ph.D.)--Virginia Commonwealth University, 2009. / Prepared for: Dept. of Pharmacology and Toxicology. Title from title-page of electronic thesis. Bibliography: leaves 166-188.

Thesis (M.S.)--Rutgers University, 2008. / "Graduate Program in Psychology." Includes bibliographical references (p. 71-77).

Thesis (Ph. D.)--University of Chicago, Dept. of History. / Includes bibliographical references. Also available on the Internet.

Thesis (M.A.)--Carleton University, 1999. / Also available in electronic format on the Internet.

Thesis (M. Ed.)--Lancaster Bible College, 2007. / Abstract. Includes bibliographical references (leaves 63-65).

Thesis (M.A.)--Dept. of Psychology, Concordia University, 1995. / Includes bibliographical references (leaves 76-84). Available also on the Internet.

Thesis (M. Ed.)--Lancaster Bible College, 2007. / Abstract. Includes bibliographical references (leaves 63-65).

Eighty male undergraduate students were randomly assigned to one of five groups in an analogue investigation of crime-intoxication on the physiological detection of deception. Sixty-four of the subjects committed a mock crime and half of these were legally intoxicated during the crime. Sixteen subjects committed no crime and served as innocent controls. Results only partially replicated those of Bradley and Ainsworth (1984). Whereas they found crime-intoxication diminished the effectiveness of both the control question test (CQT) and the guilty knowledge test (GKT), the present study found crime-intoxication diminished the accuracy of the CQT only for certain subjects; those who reported high subjective arousal during the crime. Results showed no alcohol effect on the GKT. In light of their results Bradley and Ainsworth suggested that alcohol may act through emotional or memory processes important to polygraphic examination. In a fully factorial design, the present study investigated the effects of threat during the crime and memory for crime details on polygraph outcome. As well, the effect of alcohol on these "emotion" and memory variables was examined. Memory was found to be an important variable in GKT accuracy but not important to CQT accuracy. Threat, as operationalized for the present investigation, had no effect on either the CQT or the GKT but a component of the threat variable, subjective arousal, was found to affect GKT accuracy but not that of the CQT. Raskin's (1979) two-response model of detection of deception is used to explain the results of this study although the relationship of subjective arousal to polygraph outcome is unclear and requires examination in future studies. / Arts, Faculty of / Psychology, Department of / Graduate

Alcohol dependence is a complex disease involving polygenes, environment and their interactions. Inadequate consideration of these interactions may have hampered the progress on genome-wide association studies of alcohol dependence. By using the dataset of the Study of Addiction: Genetics and Environment with 3838 subjects, we conducted a genome-wide association studies of alcohol dependence symptom count (ADSC) with a full genetic model considering additive, dominance, epistasis and their interactions with ethnicity, as well as conditions of co-morbid substance dependence. Twenty quantitative trait single nucleotide polymorphisms (QTSs) showed highly significant associations with ADSC, including four previously reported genes (ADH1C, PKNOX2, CPE and KCNB2) and the reported intergenic rs1363605, supporting the overall validity of the analysis. Two QTSs within or near ADH1C showed very strong association in a dominance inheritance mode and increased the phenotype value of ADSC when the effect of co-morbid opiate or marijuana dependence was controlled. Highly significant association was also identified in variants within four novel genes (RGS6, FMN1, NRM and BPTF), two non-coding RNA and two epistasis loci. QTS rs7616413, located near PTPRG encoding a protein tyrosine phosphatase receptor, interacted with rs10090742 within ANGPT1 encoding a protein tyrosine phosphatase in an additive × additive or dominance × additive manner. The detected QTSs contributed to about 20 percent of total heritability, in which dominance and epistasis effects accounted for over 50 percent. These results demonstrated that perturbations arising from gene–gene interaction and conditions of co-morbidity substantially influence the genetic architecture of complex trait.