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Serotonin and disorders of human disinhibition : alcohol abuse and dependence, aggression and impulsivityLeMarquand, David Gordon, 1966- January 1997 (has links)
A wealth of data supports the hypothesis that the neurotransmitter serotonin regulates the intake of ethanol, and is involved in the development of alcoholism in humans. Reduced functioning of the serotonergic system hypothetically increases alcohol intake in both animals and humans. In this thesis, it was proposed that the effect of lowered serotonergic function on alcohol intake is mediated by an increase in disinhibition. The hypothesis that lowered serotonin increases disinhibition was tested in separate groups of individuals at high risk for the development of psychopathology: nonalcoholic young men with a strong family history of paternal alcoholism, and adolescent men with previous histories of physically aggressive behavior. Lowered serotonergic synthesis (and thus presumably function) was experimentally induced through a transient dietary reduction in the availability of the amino add precursor of serotonin, tryptophan. Disinhibition was quantified using a go/no-go task previously shown to characterize psychopaths and children with attention deficit hyperactivity disorder as disinhibited. In the first study, acute tryptophan depletion had no effect on aggressive responding on a modified competitive reaction time aggression task, but increased disinhibition in young men at risk for alcoholism. This effect was independent of the tryptophan depletion-induced mood alterations. The effect tryptophan depletion on disinhibition was not replicated in the second study with previously aggressive adolescent men. A number of explanations for this were posited, including the presence of a ceiling effect. An association between disinhibition and executive functioning (cognitive abilities associated with proper functioning of the prefrontal cortex, such as working memory, planning abilities) was demonstrated in the second study. In a third preliminary study, no association between disinhibition on the go/no-go task and allelic polymorphisms of the dopamine D4 receptor
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Motivational and personality determinants of patient attrition in the outpatient treatment of alcoholismRubinstein, Dalia Adriana 04 February 2014 (has links)
M.A. (Psychology) / Please refer to full text to view abstract
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Serotonin and disorders of human disinhibition : alcohol abuse and dependence, aggression and impulsivityLeMarquand, David Gordon, 1966- January 1997 (has links)
No description available.
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Personality and sociocultural characteristics of clients in a thirty-day alcohol treatment program /Thompson, Arlene January 1981 (has links)
No description available.
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An experimental evaluation of alcohol expectancies activation and immediate alcohol consumptionLau, Hoyee Cathy 01 April 2003 (has links)
No description available.
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DRINKING - FROM A MEXICAN-AMERICAN MALE CULTURAL PERSPECTIVE.Allison, Mary Helen. January 1982 (has links)
No description available.
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Prediction of chronic alcoholism from the Minnesota multiphasic personality inventorySedlacek, Gordon Max. January 1955 (has links)
Call number: LD2668 .T4 1955 S44 / Master of Science
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THE STABILITY OF FIELD DEPENDENCE AMONG ALCOHOLICS IN TREATMENT AND THE RELATIONSHIP BETWEEN EMBEDDED FIGURES TEST PERFORMANCE AND COGNITIVE IMPAIRMENT.Lafferty, Patricia. January 1985 (has links)
No description available.
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Anxiety sensitivity and risk for alcohol abuse in young adult femalesStewart, Sherry Heather January 1993 (has links)
No description available.
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Self-awareness, self-consciousness and the self-control of drunken comportmentRoss, David Francis. January 1987 (has links)
No description available.
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