At the close of the eighteenth eentury, the secretory products of glands were believed preformed in the blood stream, from which they were expressed into the ducts through pores of different size. When it became evident, by the middle of the nineteenth century, that glands are composed of cella, the "vascular theory" was displaced by the view that the secretory material was built in the cells of the glands from cytoplasmic materials. Then, fluid derived from the blood or lymph washed this secretory product out of the cells of the glandular wall and into the lumen of the ducts. [...]

Removing a tissue from one site and placing it in another in the same animal, or a similar or a different site in another animal is known as grafting or transplanting. The transplanted tissue can be a complete organ like a kidney, or a part of an organ or cells which may be normal or malignant. Bec au se the technique is usually simple and can be applied to any organ or any animal it has a very wide appeal. [...]

Within the short history of the application of electron microscopy to cytological and histological problems, most of the emphasis has fallen on the membraneous components of the cell. Mitochondria, the Golgi apparatus, granular and agranular endoplasmic reticulum, and the nuclear envelope have all been studied intensively. There have also been many studies on specializations of the cell membrane (Fawcett, 1962). Only recently have intracellular filaments been given some attention by electron microscopists, although they still have not gained acceptance as an ubiquitous organelle in epithelia. Most descriptions of cytoplasmic filaments have been made in conjunction with studies on terminal bars or desmosomes. [...]

p.188 missing from manuscript. / Although lymphocytes have been studied for over a century,their function is still an enigma as is their precise mode of formation. These cells however, are known to be formed in the lymph nodes, spleen and in the thymus; but it is questioned whether the lymphocytes formed in spleen and nodes, organs having a mesenchymal origin. share the same function and the same mode of formation with those formed in the thymus, which organ has an epithelial origin. Moreover, while it is known that lymphocytes formed in the lymph nodes and spleen enter the lymph and blood circulation, it is not known if the thymie lymphocytes also do so for, as yet, no explanation has been provided as to how they would leave this organ. [...]

Not a rock, mineral or soil does not contain at least some iodine. Nevertheless, it is one of the scarcest of non-metallic elements on earths as to its abundance, it falls in the group of precious metals like silver, gold and platinum. It is present as inorganic salts (iodide or iodate) and to a lesser extent as complex biochemical groupings. [...]

Missing page 351. / Despite Butler's somewhat irreverant dismissal of the subject, reproduction has for many years loomed an intriguing and significant problem to the scientific world. Indeed, the intricacy whereby the many facets in the reproductive sequence unfold has presented a stimulating challenge to generations of biologists. [...]

Several recent light and electron microscopic investigations have focussed new attention upon the fibrous component of the cytoplasm of epithelial cells. A new staining method, the tannic acid-phosphomolybdic acid-amido black (TPA) technique, was briefly presented by Puchtler (1956). It consisted in treating Carnoy-fixed sections with aqueous solutions of tannic acid and phosphomolybdic acid and then in staining them with the acidic dye amido black. [...]

"Figure no. 9 omitted from numbering" -- note in manuscript. / [...] The affects of irradiation on the rat's testis will be the subject of the present work. It is hoped that the results will throw an additional light on the behaviour of the heterogenous spermatogonial population following irradiation, and in particular will explain how repopulation of the seminiferous epithelium takes place. [...]

The nucleoli of differentiating cells have long attracted the interest of investigators because of their variahility in number, volume and cytochemical features. Such variations have commonly been related to the physiochemical and cytochemical organization of the nucleolus. Specifically, the nucleolus has been considered an organelle of extreme plasticity, consisting of an apparently homogeneous ground substance (nucleolar matrix) which occasionally contains one or more vesicles (intranucleolar vacuoles or nucleolini). Relevant cytochemical and biochemical studies have indicated that these structural phases are composed of acid and basic proteins and RNA in the form of ribonucleoproteins. In brief, the classical concept of nucleolar structure recognized two intranucleolar structural phases -- nucleolar matrix and intranucleolar vacuoles -- composed of nucleolar ribonucleoproteins (reviews, Montgomery, 1898; Oates, 1942; Vincent, 1955; Stich, 1956; Hertl, 1957; Swift, 1959; Sirlin, 1962; Busch et al, 1963). [...]

It is ironic that the organ which was instrumental in the birth of the science of endocrinology (Berthold, 1849) should itself remain the subject of continual controversy as to the precise role hormones play in its functioning. The testis unlike the other endocrine organs, does not lend itself readily to the classical procedure of extirpation, for with ablation of the endocrine function one has of necessity also removed the primary target in the form of the seminiferous tubules. [...]