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The goal of the present investigation was to evaluate the role of the pulmonary diffusion capacity (as measured by DLco) in relation to exercise-induced hypoxemia in elite athletes working at near maximal exercise intensities. Twenty-four elite cyclists were submitted to a direct measurement of VO$ sb2$ max on cycle ergometer which permitted classification into one of two groups. "Desaturaters" (N = 13) if oxyhemoglobin saturation (SaO$ sb2$%), as determined by finger oxymetry, fell below 91% or "non-desaturaters" if SaO$ sb2$% remained above 91%. Subsequent determinations of the transfer capacity for CO (DLco) were made using a 3 second breath-hold technique (Gould 2400/2450), at rest as well as at 60% and 90% of previously determined VO$ sb2$ max ($>$4.0 1/min). The results show an increase in DLco from rest to the first exercise intensity (desat: 41.7 $ pm$ 5.7 to 55.1 $ pm$ 4.7; non-desat: 41.1 $ pm$ 5.8 to 57.2 $ pm$ 6.9 mlsCO/mmHg/min) without much further increase to the maximal workload (desat: 61.0 $ pm$ 6.0; non-desat: 61.4 $ pm$ 9.5 mls CO/mmHg/min). No significant differences in DLco were found between the two groups at rest or either of the two exercise intensities. Significant differences between the desat and non-desat groups were found for FVC, post-exercise FEF$ sb{25-75 %}$, and VE/VO$ sb2$. / The present results are in agreement with previous reports showing arterial desaturation in 50% of highly-trained subjects when VO$ sb2$ max $>$4.0 1/min. The present investigation cannot clearly establish the role of DLco in this response. (Abstract shortened by UMI.)

Dissertation (PhD)--University of Stellenbosch, 2007. / Bibliography. Also available via the Internet.

Thesis (M.S.)--University of British Columbia, 2007. / Includes bibliographical references (leaves 49-67). Also available online (PDF file) by a subscription to the set or by purchasing the individual file.

Thesis(M.S.)--Auburn University, 2005. / Abstract. Vita. Includes bibliographic references.

Thesis (Ph.D.)--University of Adelaide, Dept. of Obstetrics and Gynaecology, 2004. / "December 2003" Includes bibliographical references (leaves 183-224).

Thesis (Ph. D.)--University of Sydney, 1998. / Title from title screen (viewed Apr. 15, 2008). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Dept. of Respiratory Medicine, Royal North Shore Hospital, Faculty of Medicine. Degree awarded 1998; thesis submitted 1997. Includes bibliography. Also available in print form.

Thesis (M.Sc.) - Carleton University, 2006. / Includes bibliographical references (p. 114-129). Also available in electronic format on the Internet.

Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 91-134) Also available in print.

Thesis (M.S.)--University of Toledo, 2007. / Typescript. "Submitted as partial fulfillment of the requirements for The Master of Pharmaceutical Sciences." "A thesis entitled"--at head of title. Bibliography: leaves 53-55.