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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
21

Characterization of novel members of the Streptomyces violaceusniger clade and characterization of antibiotic synthesis genes from Streptomyces lydicus WYEC 108 /

Kang, Min Jin. January 1900 (has links)
Thesis (Ph.D.)--University of Idaho, May 2006. / Major professor: Donald L. Crawford. Abstract. Includes bibliographical references. Also available online in PDF format.
22

Synthesizing Antifungal Agents

Tran, Linh N. January 2007 (has links) (PDF)
No description available.
23

Studies toward the total synthesis of pseudolaric acid A

Chen, Bin, 陳斌 January 2001 (has links)
published_or_final_version / Chemistry / Doctoral / Doctor of Philosophy
24

Mechanisms of antifungal resistance in pathogenic fungi

Joseph-Horne, Tim January 1995 (has links)
No description available.
25

Studies towards the synthesis of the macrolide portion of ulapualide A

Reader, Michael January 1995 (has links)
No description available.
26

A study of plant lectins and antifungal proteins with emphasis on those of leguminous origin. / CUHK electronic theses & dissertations collection

January 2005 (has links)
A heterodimeric 60 kDa lectin was isolated from the ground bean ( Vigna sesquipedalis cv ground bean). Its hemagglutinating activity was inhibited by polygalacturonic acid and not by galacturonic acid and other simple monosaccharides. Ground bean lectin exhibited mitogenic activity on murine splenocytes, reduced the viability of hepatoma and leukemia cells, and exerted an inhibitory activity toward HIV-1 reverse transcriptase. / A homodimeric 30-kDa glucose/mannose-specific lectin was purified from emperor banana. In contrast to Con A, the mitogenic activity of emperor banana lectin (EBL) toward mouse splenocytes but not its NO stimulatory effect toward mouse macrophages could be abrogated by 200 mM glucose. It also inhibited proliferation of tumor cells and inhibited HIV-1 reverse transcriptase. / A homodimeric 60-kDa lectin with specificity toward mannose, glucose and rhamnose and substantial N-terminal sequence to Concanavalin A has been isolated from Canavalia gladiata legumes. In contrast to Con A, the mitogenic activity of knife bean lectin toward mouse splenocytes but not its antiproliferative activity toward tumor cells could be abrogated by 200 mM glucose. The lectin inhibited HIV-1 reverse transcriptase, but did not exhibit antifungal activity. / A homotetrameric 120-kDa agglutinin was isolated from haricot bean seeds. It manifested a weaker mitogenic activity than concanavalin A toward mouse splenocytes and exhibited antiproliferative activity toward several tumor cell lines. / A plant defensin-like peptide, with a molecular mass around 6-kDa, was purified from the seeds of Chinese lima beans (Phaseolus lunatus L. ). Phld exerted an antifungal activity and an antibacterial action. Phld could reduce the activity of HIV-1 reverse transcriptase and inhibit translation in a cell-free rabbit reticulocyte lysate system. (Abstract shortened by UMI.) / Defense proteins are produced by a wide range of organisms including mammals, insects, plants, fungi and bacteria. In this study, focus was placed on 2 kinds of defense proteins in plants, namely, lectins/hemagglutinins and defensin-like peptides/defensins. Three lectins, one hemagglutinin (i.e. lectin whose hemagglutinating activity cannot be inhibited by simple saccharides), one defensin and two defensin-like peptides were isolated from 5 species of plants. The isolation procedure included different chromatographic techniques, involving ion exchange chromatography, affinity chromatography and gel filtration. / Wong Ho. / "August 2005." / Adviser: Tzi Bun Ng. / Source: Dissertation Abstracts International, Volume: 67-07, Section: B, page: 3785. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2005. / Includes bibliographical references (p. i-xxvii). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract in English and Chinese. / School code: 1307.
27

Study of antifungal proteins from plant storage organs. / CUHK electronic theses & dissertations collection

January 2005 (has links)
Antifungal proteins belong to a group of plant defense proteins, present in different plant tissues ranging from leaves, stems, roots to seeds. Upon fungal invasions, these proteins accumulate at the infection site to inhibit the growth of pathogens. Some antifungal proteins were found to have antifreeze and antiviral characteristics as well. Antifungal proteins are structurally diverse. Thaumatin-like proteins, chitinases, ribosome inactivating proteins, defensins, cyclophilin-like proteins and miraculin-like proteins are members of the family of antifungal proteins. There are antifungal proteins with other structures such as cysteine protease inhibitors and peptides. Apart from plant defense, antifungal proteins have been reported to affect the growth of murine immune cells including splenocytes, macrophages and bone marrow cells, as well as leukemia cells. / In my study, five antifungal proteins were isolated from plant storage tissues that were bulbs and seeds abundant in proteins, comprising a chitinase-like antifungal proteins from black turtle beans (Phaseolus vulgaris cv. black turtle), an 8-kDa antifungal peptide from green chickpea ( Cicer arietinum cv green chickpea), two thaumatin-like proteins from two kinds of chestnut (Castanopsis chinensis and Castanea mollissima) and a 7.1-kDa antifungal peptide from the Chinese daffodil (Narcissus tazetta var. chinensis). In the majority of cases, the antifungal proteins were unadsorbed on DEAE-cellulose and adsorbed on Affi-gel blue gel, CM-cellulose and Mono S. They showed different antifungal potencies on various phytopathogenic fungi examined including Botrytis cinerea, Fusarium oxysporum, Mycosphaerella arachidicola and Physalospora piricola. Only the daffodil and Castanopsis antifungal proteins were active on all four fungal species. The remaining three antifungal proteins inhibit 2-3 of the 4 fungi. / The purified proteins were characterized for various biological activities such as the inhibitory activity on HIV-1 reverse transcriptase and cell-free translation in a rabbit reticulocyte system. All proteins except those from daffodil bulbs and black turtle beans exhibited HIV-1 reverse transcriptase inhibitory activity. The activity of purified proteins on the proliferation of normal and tumor cells in vitro, including murine splenocytes and leukemia L1210 cells, was also studied. Daffodil antifungal protein was the only protein found to have a stimulatory activity on mouse splenocytes and an inhibitory activity on leukemia cells. (Abstract shortened by UMI.) / Chu Kin-tak. / "June 2005." / Adviser: T. B. Ng. / Source: Dissertation Abstracts International, Volume: 67-07, Section: B, page: 3574. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2005. / Includes bibliographical references (p. 175-183). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract in English and Chinese. / School code: 1307.
28

AN ANTIBIOTIC WITH ANTIFUNGAL AND ANTIVIRAL PROPERTIES

Mann, Elton Willard, 1914- January 1966 (has links)
No description available.
29

A study of the synthesis, antimycotic action, and toxicity of diiodo-para-aminosalicylic acid

Bethmann, William Miner, 1928- January 1952 (has links)
No description available.
30

Advances in yeast and mold monodrug and combination drug antifungal susceptibility testing

Wetter, Tracy Jane. January 2004 (has links) (PDF)
Thesis (Ph. D.)--Montana State University--Bozeman, 2004. / Typescript. Chairperson, Graduate Committee: Rick P. Morrison. Includes bibliographical references (leaves 207-235).

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