Magister Public Health - MPH / Background: Human Immune Deficiency Virus (HIV) is a public health challenge worldwide. Antiretroviral therapies (ART) are medications that treat HIV virus infection by suppressing the virus and stopping progression of HIV disease, and that improve quality of life. People initiated on ART need to adhere to their treatment for the rest of their lives. In 2016, there were 7,1 million people (age 15-49) in South Africa living with HIV, representing 19 % of the global HIV burden, with 56% of the adults on ART. Life expectancy of South Africans for both males and females improved between 2009 and 2011 because of ART treatment. People lost to follow up while on ART compromise their own health and the long term positive benefits of the ART regimen, and hence there is a growing emphasis to improve the retention of people who are already on treatment. Aim: This study was conducted examining HIV positive South African Clothing and Textile Workers Union (SACTWU) members who are currently on ART treatment and had previously been lost to follow up (LTFU) from ART care. The study aimed to explore factors associated with LTFU of clients on ART treatment and care among the South African Clothing and Textile Union members living with HIV and attending the SACTWU Worker Health Program Clinic.

The purpose of this study was to evaluate the antiretroviral therapy program in primary health care settings in Lesotho. Mixed methods research using a convergent parallel mixed methods design was used to collect both quantitative and qualitative data which were analysed during the same phase of the research process. Two groups of participants participated in the study, the registered nurse group was composed of registered nurses/midwives/nurse clinicians involved in ART service provision and the second group was composed of adults aged 18 years and older who were HIV/AIDS positive. Quantitative data had a compliance rate of 92% and it were analysed using SPSS (23). Qualitative data were analysed using constant comparison analysis and seven themes, fourteen categories and twenty two sub-categories emerged from the data analysis. Findings of the study revealed that the majority of PHC facilities were staffed by registered nurse midwives and nurse clinicians who were qualified, confident, knowledgeable and competent in the execution of duties. Generally there were a large number of patients that sought ART services which were offered on a weekly basis although there was variation in the actual number of days the services were provided. The time patients spent seeking ART services varied across the facilities and ARVs and other drugs were usually available. Challenges in the delivery of ART services included unsatisfactory staffing resulting in the provision of inadequate services and work overload, lack of knowledge of some patients, use of incentives by some partners and too many partners being involved in ART, inadequate documentary evidence and stigma pertaining to the HIV status of individuals. Furthermore, ARVs were reported to make patients feel hungry hence resulting in lack of satisfaction in ART services, ART services were inadequate due to dysfunctional equipment and some patients had been lost due to inability to screen for cancer and there was incomplete monitoring and evaluation of the ART program. However, participants in this study generally showed their acknowledgement of the ART services as they generally improved their health status despite the many challenges that were being faced. / Health Studies / D.Litt.et Phil. (Health Studies)