Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2018-03-15T15:58:28Z No. of bitstreams: 1 EDUARDO_MADRUGA_LOMBARDO_DIS.pdf: 563577 bytes, checksum: 75bb1d6f556f2f712acc1396b93b1ef9 (MD5) / Approved for entry into archive by Tatiana Lopes (tatiana.lopes@pucrs.br) on 2018-03-27T11:58:27Z (GMT) No. of bitstreams: 1 EDUARDO_MADRUGA_LOMBARDO_DIS.pdf: 563577 bytes, checksum: 75bb1d6f556f2f712acc1396b93b1ef9 (MD5) / Made available in DSpace on 2018-03-27T12:03:50Z (GMT). No. of bitstreams: 1 EDUARDO_MADRUGA_LOMBARDO_DIS.pdf: 563577 bytes, checksum: 75bb1d6f556f2f712acc1396b93b1ef9 (MD5) Previous issue date: 2017-01-20 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The objective of this systematic review was to answer the following question: "Does the use of glucosamine and chondroitin decrease pain and improve function in patients with osteoarthritis of the temporomandibular joint?" A search in the literature guided by PRISMA-P Statement was conducted using the PubMed, EMBASE and Cochrane Library databases and the OMNIS and VHL tools. The search terms that guided the search were: "glucosamine", "chondroitin", "temporomandibular" and "osteoarthritis". The data extraction was performed in 4 randomized clinical trials that presented according to the eligibility criteria. The selected studies were also submitted to methodological quality evaluation. Final considerations: Although RCTs show positive results regarding chondroprotective agents, there is a need for more methodological rigor in their construction. / O objetivo do projeto desta revis?o sistem?tica foi responder a seguinte quest?o: ?o uso da glicosamina e da condroitina diminui a dor e melhora a fun??o em pacientes acometidos por osteoartrite da articula??o temporomandibular??.Uma busca na literatura norteada pelo PRISMA-P statement foi conduzida utilizando as bases de dados PubMed, EMBASE e Cochrane Library e as ferramentas OMNIS e BVS. Os termos de busca que orientaram a busca foram: ?glucosamine?, ?chondroitin?, ?temporomandibular? e ?osteoarthritis?. A extra??o de dados foi realizados em 4 ensaios cl?nicos randomizados que apresentaram-se de acordo com os crit?rios de elegibilidade. Os estudos selecionados ainda foram submetidos ? avalia??o da qualidade metodol?gica. Considera??es finais: Embora os ECRs apresentem resultados positivos a respeito de agentes condroprotetores, h? necessidade de maior rigor metodol?gico na sua constru??o.