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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Effects of mus mutations on mitotic recombination in Aspergillus nidulans

Zhao, Ping, 1955- January 1990 (has links)
Nine mutagen sensitive (mus) mutants of Aspergillus nidulans were analyzed for effects on recombination. These mus show increased sensitivity to various mutagens; several were UV-sensitive. The majority were sterile in homozygous crosses homozygous mus diploids were essential to test for mitotic recombination. / Two distinct tests were used: intergenic recombination between colour mutations and their centromeres; and, intragenic recombination between two distinguishable adE alleles. Both hyper- and hypo-rec mus mutations were identified, with 15- to 20-fold differences between them. Three mutations musN, musO, and musQ had greatly elevated recombination frequencies. Only one, musL significantly reduced recombination but consequently increased malsegregation. / Analysis of the genotype of ad$ sp{+}$ recombinants, from musN and musL diploids, revealed qualitative differences from mus$ sp{+}$. musN enhanced mitotic crossing over but not gene conversion; while musL reduced the frequency of simple convertants but increased that of complex homozygous ad$ sp{+}$ genotypes. Mitotic conversion and crossing over, generally associated with each other, were uniquely affected in such mus diploids.
2

Effects of mus mutations on mitotic recombination in Aspergillus nidulans

Zhao, Ping, 1955- January 1990 (has links)
No description available.

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