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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
151

Production and Characterisation of a chimaeric human IgE antibody, recognising der P 1, and its chimaeric human IgG1 anti-idiotype : the prospect of idiotypic-anti-idiotypic interactions as an intervention strategy for allergy

Furtado, Patricia Brotto January 2001 (has links)
No description available.
152

The induction of cyclooxygenase-2 in cultured human airway smooth muscle cells and its role in regulating the cell functions

Pang, Linhua January 1999 (has links)
No description available.
153

A model for non-atopic eosinophilic inflammation in the athymic rat

Stoten, Adam January 2001 (has links)
No description available.
154

Variants of the #beta# subunit of the high affinity IgE receptor and atopy

Li, Airong January 1996 (has links)
No description available.
155

Asthma Management Practices In Two Ontario School Districts: Applying Knowledge to Action

Thomas, Nicola 25 November 2013 (has links)
Background: School settings are one of the most crucial context for asthma management second only to a child’s home. Today school administrators are faced with many challenges, not only are they responsible for students' learning needs but they also manage complex behavioural and health issues including asthma. Most do not have standardized plans regarding asthma management. Objectives: 1) Systematically review the research literature related to asthma management within the school setting. 2) Determine current asthma management practices as reported by school administrators. 3) Explore experiences and barriers to asthma management practices with school administrators. Method: Guided by the Knowledge to Action framework, the study was divided in three phases using a planned action approach and included an integrative synthesis of the evidence, an administrators’ survey, and an administrator’s meeting. Findings: Phase One: Following a search using three databases, 67 articles were critiqued. The literature illustrates that many countries have established “asthma friendly schools” legislation that includes process for identifying children with asthma, right to self-carry and administer medications, enhancing communication and cooperation between school staff, parents, and children with asthma, reducing triggers in school environment, and effective policies that make legislation a functioning reality within schools. Phase Two: Ninety-seven surveys were distributed within two district school boards with 61 completed surveys returned (63% response rate). Key findings included underestimation of the prevalence of asthma, no standardized process for identifying children with asthma, staff training deficiency for recognizing and responding to asthma exacerbations, lack of individual asthma action plans for children, absence of programs to support current legislation and best practice guidelines. Communication was the most common barrier identified by school administrators. Phase Three: Two principals in an administrator’s meeting validated the survey results. Participants were not familiar with the concept of asthma friendly school, asthma prevalence rates, or free school asthma resources. Asthma Action Plans were not universally understood as individualized written plans but rather a generalized first aide response plan. Conclusion: There are knowledge and practices gaps placing children with asthma at risk for exacerbation and death within school setting. Administrators want to partner to facilitate optimal asthma management within the school setting. / Thesis (Master, Nursing) -- Queen's University, 2013-11-25 11:38:01.902
156

Effect of acute and chronic pressure-threshold inspiratory muscle training on upper and lower airway function

How, Stephen Christopher January 2010 (has links)
There is evidence to suggest that inspiratory muscle training (IMT) may influence the functional properties of the muscles of the upper (UA) and lower (LA) airway. However, the nature and functional relevance of this influence is currently unclear. This thesis examined the effect of acute and chronic IMT in the context of UA and LA function. The ability of IMT to activate the UA dilator muscles, genioglossus (GG) and geniohyoid (GH), was examined using magnetic resonance imaging (MRI), as was the effect of chronic training on these muscles. In addition, the effect of acute and chronic IMT upon LA resistance (Rrs) and function was investigated in people with asthma using the Forced Oscillation Technique and conventional spirometry. For the UA, an acute bout of IMT at 60% maximal inspiratory mouth pressure (MIP) resulted in significant GG and GH activation (P < 0.001) as demonstrated by increases in the transverse relaxation time of muscle water (T2). Despite this, MRI was unable to detect any effect of chronic IMT upon UA function. For the LA, the usual increase in Rrs, following deep inhalation (DI) in people with asthma was attenuated with both single and multiple breaths against a pressure-threshold load equal to 50% MIP. However, six weeks IMT had no effect on baseline airway function or response to DI. In conclusion, an acute effect of pressure-threshold IMT upon UA and LA function was demonstrated. A strong rationale for a beneficial influence of chronic pressure-threshold IMT was therefore demonstrated. However, the data were insufficient to either reject, or accept the hypothesis that IMT exerts more than a transient influence upon UA and LA function, but insights are presented that support the need for further investigations.
157

Self-efficacy and childhood asthma : an investigation of psychological factors

Slater, Joanne Tracy January 2001 (has links)
Childhood asthma is a chronic condition affecting up to one in every seven children. Self-management programs have been developed to help improve children's abilities to both manage and cope with their asthma. If these programs are to be fully effective, an understanding of the psychological factors that influence children's sense of competence to manage their condition is required. This study aimed to identify psychological variables that may influence children's asthma self-efficacy including children's health locus of control, child's attitudes toward illness and children's level of anxiety. The relationship between children's level of asthma knowledge and their sense of competence to manage the illness was explored. The importance of parent's level of asthma knowledge and parent asthma self-efficacy was also examined in relation to children's level of asthma self-efficacy. The study adopted a within group cross-sectional approach. Children aged 7-15 years of age with asthma were invited to participate in the research. Data were collected on 71 children and their parents based on self-report measures rating child and parent asthma self-efficacy and asthma knowledge, child health locus of control, child attitudes toward illness and anxiety. A correlational design was employed to test for associations and relationships between children's asthma self-efficacy and the factors noted above. Results will be given and discussed with reference to previous research findings with conclusions reached.
158

Appropriateness and Use of Medications by Patients with Persistent Asthma in a Community Health Center

Guzman-Lopez, Mayra January 2017 (has links)
Class of 2017 Abstract / Objectives: A chart will be used to assess the need for the asthma education program. The chart review aims to: analyze the refill history of asthma medications along with verifying adherence via electronic health record and assess if patients are getting appropriate asthma therapy per 2007 NHLBI asthma guidelines. Methods: The patient’s MHC Healthcare electronic record profile and pharmacy refill record will be accessed. The information that will be obtained from the electronic health record will be: ethnicity, age, sex, allergic rhinitis diagnosis, flu vaccine status, pneumonia vaccine status, GERD diagnosis, spirometry measure if available, use of prednisone for exacerbation, prescribed asthma therapy, and provider’s (MD, NP, PA, etc)’s notes that might indicate nonadherence. The information that will be obtained from the pharmacy record are controller and rescue medication refill history. The information will be recorded in paper data collection forms and electronic versions will be saved to the secure college of pharmacy workgroup. The raw physical information described above will be stored in a locked cabinet at MHC healthcare pharmacy inside the pharmacy director’s office and the de-identified information will be stored in the secure workgroup. Results: Conclusions:
159

Personalized asthma medication

Schneider, Anna-Maria January 2015 (has links)
The aim of my master degree project of Advanced Product Design was to develop a monitoring and medication device to empower people who are suffering from asthma. Asthma is a major non-communicable disease characterized by recurrent attacks of breathlessness and wheezing. It is not possible to cure asthma, but appropriate management can control the disease and enable people to enjoy a good quality of life. Asthma varies in severity and frequency from person to person and not every asthmatic will require the same level of treatment. Also asthma conditions can vary over time and the level of airways inflammation has to be reviewed and medication has to be adjusted. Asthma diagnostic takes place at a point-of-care environment and is usually based on the pattern of symptoms, response to therapy over time and by objective parameters like lung function tests. My degree project was focused on a home used diagnostic and medication system in order to adjust the dosage of asthma medication on a more frequently basis.
160

Asthma at night : observations on the interrelations of asthma and sleep

Catterall, James Richard January 1986 (has links)
Part I of the thesis contains a brief review of the clinical importance of nocturnal asthma, and an account of the methods used to study breathing during sleep. The original work of the thesis is divided into three further parts: In Part II are described studies of breathing and oxygenation during sleep in normal subjects. These studies were performed to establish a normal range of apnoea, hypopnoea and oxygenation during sleep and to determine the effects of age and sex on these variables. Part III contains the results of similar studies in patients with asthma. Breathing patterns and oxygenation during sleep in asthmatic patients were compared with those of normal subjects and those of patients with chronic bronchitis and emphysema. The studies described in Part IV were designed to explore the relationship between sleep and bronchoconstriction. I wished to establish whether sleep was essential for nocturnal bronchoconstriction and to determine whether bronchoconstriction was associated with one particular stage of sleep. The results are summarised at the end of each section, and the clinical implications of the results are discussed in Part V.

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