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Formation and reactions of salicylaldehyde-Schiff bases and zinc complexes: equilibrium and kinetic study of vitamin B₆ model systems /McQuate, Robert Samuel January 1973 (has links)
No description available.
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Formation and transamination of pyridoxal-5'-phosphate Schiff bases and their copper(II) complexes : studies of a vitamin B₆ model system /Hershey, Stephen Alan January 1976 (has links)
No description available.
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Part I. Rates of transimination of vitamin B₆?Schiff bases.; Part II. Equilibria and rates of transfer of iron between various ligands and transferrin /Weng, Shu-Huan January 1979 (has links)
No description available.
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A visual analysis of Boston metropolitan shoreline from Dorchester Bay to Cohasset HarborPeterson, Richard Arvid January 1961 (has links)
Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of City Planning, 1961. / Includes bibliographical references (leaf 55). / by Richard Arvid Peterson. / M.C.P.
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Effect of vitamin B₆ and calcium pantothenate on the metabolism of unsaturated fatty acidsCheng, Wu-Chieh. January 1949 (has links)
Call number: LD2668 .T4 1949 C49 / Master of Science
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The influence of exercise on vitamin B-6 metabolismMunoz, Kathy Denise 29 January 1982 (has links)
The present study was designed to investigate the
effects of exercise on vitamin B-6 metabolism. Four groups
of subjects (intermittent, college, untrained, and high school)
consisting of nineteen male and two female individuals, participated
in the study. The subjects exercised either on a
bicycle ergometer, by running three 1500 meter intervals, or
both. Blood samples drawn prior to exercise (pre), after exercise
(post), and 30 minutes after exercise (30 minute post),
were analyzed for plasma pyridoxal 5'-phosphate (PLP), plasma
B-6 (PB6), glucose, hemoglobin and hematocrit. A 24-hr urine
collection the day before and the day of exercise was analyzed
for urinary B-6 (UB6), 4-pyridoxic acid (4PA), creatinine, and
urea nitrogen.
The dietary intake of the four groups was greater than the
RDA in vitamin B-6, riboflavin, thiamin, niacin, vitamins A and
C, calcium and iron. The B-6/protein ratios of the college and
untrained groups were adequate while the high school group's
ratios were considered inadequate.
The bicycle ergometer had a significant effect on the plasma
PLP levels of the college and untrained groups (P< 0.005) and PB6
levels of the college group following exercise (P< 0.005). The
30 minute post plasma PLP levels were significantly lower for
the college group (P< 0.005).
During the run, the college group had significantly higher
post exercise levels of plasma PLP (P< 0.005) and PBS (P< 0.005}
as compared to the pre exercise sample. The high school group
also had significantly higher levels of plasma PLP following,
exercise for all three runs (P< 0.005, P< 0.025, and P< 0.01,
respectively) as well as higher PB6 levels (P< 0.025, P< 0.01,
and P< 0.025, respectively).
The college athletes had a greater percent change in plasma
PLP (P < 0.01) from the pre to post sample during the run as
compared to the high school athletes.
Urinary B-6 and 4PA were not significantly altered during
either exercise suggesting a shift in PLP and the unphosphorylated
forms of vitamin B-6 from one compartment to another. The significantly
higher levels of plasma PLP and PB6 following exercise
were attributed to an increased utilization of glycogen phosphorylase
in the skeletal muscle with a subsequent release of PLP. / Graduation date: 1982
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The effect of pyridoxine supplementation on erythrocyte aminotransferase activity in manWang, Ann-gau Nancy 03 March 1982 (has links)
The effect of pyridoxine (PN) supplementation on the activities
of erythrocyte alanine aminotransferase (EAlaAT) and aspartate aminotransferase
(EAspAT) was observed in five men, aged 22 to 25 years.
The subjects received a constant diet containing 1.34 mg of vitamin
B-6 Monday through Friday of each week during this five-week study.
Starting on day 6 of week 1, the subjects were given orally 5 mg PN
daily, except on Tuesday and Thursday of each week when they were given
either no PN or 2 mg of vitamin B-6 in the form of crystalline PN or
as food. Basal and pyridoxal phosphate (PLP)-stimulated EAlaAT and
EAspAT activities were determined weekly. Both basal and PLPstimulated
activities of the two enzymes increased after only three
days of PN supplementation and continued to increase throughout the
four weeks of PN supplementation; percent stimulation by PLP added in
vitro decreased concomitantly. It is suggested that the binding of PLP
to erythrocyte apoaminotransferases may be another reservoir for
vitamin B-6. / Graduation date: 1982
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The effect of vitamin B-6 supplementation on lymphocyte responsiveness in independently-living elderly personsTalbott, Mary Catherine 08 January 1986 (has links)
The effect of pyridoxine (PN) supplementation on lymphocyte
responsiveness was investigated in 15 elderly volunteers (aged
65-81 years) by measuring lymphocyte proliferation to T and B cell
mitogens, lymphocyte subpopulations with monoclonal antibodies
(T3, T4, T8) and plasma pyridoxal 5'-phosphate (PLP) concentration
at pre-supplementation and after 1 and 2 months of daily
supplementation. Eleven subjects received 50mg of PN-HC1 and 4
received a placebo. Dietary histories were also evaluated for
Intake of vitamin B-6, protein and kilocalories. Mitogens used
for the stimulation of lvmphocyte proliferation were phytohemagglutinin (PHA), concanavalln A (Con A), pokeweed mitogen
(PWM), and Staphylococcus aureus Cowain I (SAC). Plasma PLP was
measured by a radio tracer method. Before supplementation, mean
PLP of the 15 subjects was 31.7 +/- 14.1 nM; 5 PN and 3 placebo
treated subjects had low PLP levels. After 1 and 2 months of
PN-HCl supplementation, the PLP levels Increased by 195 +/-88 nM
and 201 +/-84 nM, respectively. Lymphocyte proliferation In
response to PHA, PWM, and SAC Increased significantly (p < 0.05)
with PN supplementation. Among PN-treated subjects, Ivmpbocyte
blaatogenesls was significantly greater In response to Con A and
PWM in individuals whose initial PLP was low. Percentages of T3+
and T4+, but not T8+ cells increased significantly In PN-treated
individuals. These results suggest that vitamin B-6 status is
important in maintaining immunocompetence in the elderly. / Graduation date: 1986
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The effect of glucose and fructose ingestions on vitamin B-6 and fuel metabolism during prolonged, continuous exercise in trained malesSeitz, Julia Ann 17 January 1986 (has links)
The study was designed to indirectly understand muscle
glycogen utilization during prolonged exercise when either
glucose, fructose, or water is ingested. Eight trained
adult males exercised on a cycle ergometer at 58±7% of V02
max for 2 h on 2-4 occasions. At 0 minutes of exercise and
at 30-minute intervals throughout the exercise, the
subjects ingested 200mL of fluid containing either glucose,
fructose, or plain water in a double-blind, randomized
fashion. The carbohydrate (CHO) fluid concentration was
based on each subject's body weight (BW): Ig CHO X kg⁻¹ BW
X L⁻¹ water and ranged from 5.8-9.2% (average=7.5%) of BW.
Blood samples were collected from subjects at rest and
immediately prior to fluid ingestion during exercise and
analyzed for hematocrit, hemoglobin, and plasma levels of
glucose, lactate, and pyridoxal 5'-phosphate (PLP). ANOVA
showed no significant difference among treatments at any
time of exercise for mean plasma lactate and PLP levels (p > 0.05). Although not significant, mean plasma lactate and PLP concentrations tended to be lower when glucose was
consumed as compared to fructose and water. The mean
plasma glucose level, however, uas significantly different
among treatments at specific time points of exercise (p < 0.05). During exercise, mean plasma glucose decreased, and there was a higher plasma glucose level when glucose and
fructose fluids were ingested as compared to water. At 60
minutes of exercise, this difference uas evident for both
glucose and fructose ingestion (p < 0.05). At 90 and 120
minutes of exercise, fructose ingestion produced a
significantly higher mean plasma glucose level than either
water or glucose ingestion (p < 0.05). It is hypothesized
that the higher plasma glucose levels provided a greater
blood glucose supply to working muscles, thereby sparing
muscle glycogen stores. The findings indicate that for the
long-term exerciser, consumption of a 5.8-9.2% fructose
solution may promote less muscle glycogen utilization than
either glucose or water, thereby possibly increasing
endurance. / Graduation date: 1986
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Effect of vitamin B-6 supplementation before strenuous exercise on restoration of plasma urea and ammonia levelsCampuzano, Gloria 11 March 1988 (has links)
The objectives of this study were a) to determine
if pyridoxine (PN) supplementation increases the rate at
which plasma urea and ammonia return to basal levels,
following exercise, b) to determine, by open circuit
calorimetry, the utilization of carbohydrates, and c) to
further understand vitamin B-6 metabolism during and
following strenuous exercise. Six male athletes (age 26 ±
5 years and VO₂ max 66.4 ± 6.9 ml/kg/min) exercised for 1
hour on a cycle ergometer at 72% VO₂ max at two points
during a 17 day study. For the first 8 days subjects
received daily a placebo solution, while during the next
half they received a PN dose (20 mg). Subjects consumed
a constant diet the day before, day of, and day after the
exercise test. Blood samples were taken the day of the
exercise test at fasting (Fl), pre-exercise (PE), during exercise (DE), 1 min post exercise (I'P), 6 hour post
exercise (6hP), and the day after the exercise test at
fasting (F2). Plasma was analyzed for ammonia, urea, and
pyridoxal 5'-phosphate (PLP). ANOVA showed no
significant difference between treatments for either
plasma ammonia or urea. While there was a significant
increase (p<0.001) in plasma ammonia levels over time
with the placebo, with supplementation the increase over
time was not significant. With PN supplementation,
plasma PLP levels were significantly correlated (p<0.05)
with plasma ammonia levels at I'P. A slight decrease in
plasma urea concentration was observed with the PN
treatment at PE, DE, I'P, and 6hP. It was concluded
that PN may reduce adverse consequences of plasma
ammonia and urea seen with exercise. On the other hand,
pyridoxine supplementation may produced a shift in the
utilization of substrates of the subjects. Metabolic
rate results showed that the contribution of
carbohydrates as a energy source increased from 43.5 ±
13.7% with the placebo, to 52.0 ± 6.7% with the PN
treatment (not significantly different). This observation
lead to the conclusion that PN supplementation decreases
glycogen stores compared to the glycogen stores without
supplementation. Since the findings from this study
suggest slightly more rapid plasma ammonia and urea
restoration but decreased glycogen stores, they do not
provide evidence for or against an increased need for vitamin B-6 in persons that are involved in strenuous
exercises of medium duration. / Graduation date: 1988
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