Nonparametric tests are used to test hypotheses when the data at hand violate one or more of the assumptions for parametric tests procedures. The test is an ordered alternative (nondecreasing) when there is prior information about the data. It assumes that the underlying distributions are of the same type and therefore differ in location. For example, in dose-response studies, animals are assigned to k groups corresponding to k doses of an experimental drug. The effect of the drug on the animals is likely to increase or decrease with increasing doses. In this case, the ordered alternative is appropriate for the study. In this paper, we propose eight new nonparametric tests useful for testing against nondecreasing order alternatives for a mixed design involving randomized complete block and balanced incomplete block design. These tests involve various modifications of the Jonckheere-Terpstra test (Jonckheere(1952), Terpstra(1954)) and Alvo and Cabilio’s test (1995). Three, four and five treatments were considered with different location parameters under different scenarios. For three and four treatments, 6,12, and 18 blocks were used for the simulation, while 10, 20, and 30 blocks were used for five treatments. Different tests performed best under different block combinations, but overall the standardized last for Alvo outperformed the other test when the number of treatments and number of missing observations per block increases. A simulation study was conducted comparing the powers of the various modification of Jonckheere-Terpstra (Jonckheere(1952), Terpstra(1954)) and Alvo and Cabilio’s (1995) tests under different scenarios. Recommendations are made.

Hadamard matrices are defined, and their basic properties outlined. A survey of historical and recent literature follows, in which a number of existence theorems are examined and given context. Finally, a new result for Hadamard matrices over $\Z_2$ is presented and given a graph-theoretic interpretation. / Master of Science