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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Efeito do tratamento periodontal básico no controle glicêmico e da inflamação de pacientes com Diabetes Mellitus tipo 1 e tipo 2: Ensaio Clínico Controlado / Effect of basic periodontal treatment on glycemic control and inflammation in patients with diabetes mellitus type 1 and type 2: Controlled Clinical Trial

Lopes, Claudia Camila Peruzzo 06 April 2016 (has links)
Made available in DSpace on 2017-07-10T14:57:33Z (GMT). No. of bitstreams: 1 claudia_ lopes.pdf: 1090267 bytes, checksum: 0046c70242b43bfef4a590933029e9c2 (MD5) Previous issue date: 2016-04-06 / Periodontitis is often associated with diabetes mellitus (DM) and can be considered a chronic complications. Growing evidences suggests that periodontal disease has an adverse effect on glycemic control and an active role in the pathophysiology of complications related to DM, as in type 1 diabetes mellitus as in type 2 diabetes mellitus. Objective: Compare the response of basic periodontal therapy in diabetes patients with diabetes type 1 and type 2. Methodology: We selected 70 patients with periodontitis, these were divided into three groups: Control group (systemically healthy patients); Group test 1 (patients with type 1 diabetes mellitus); Group test 2 (patients with type 2 diabetes mellitus). The groups received basic periodontal treatment after clinical examination. The analyzis were performed at 0, 3 and 6 months, clinical parameters including periodontal and gingival crevicular amount of fluid. They were measured glycated hemoglobin (HbA1c) and prostaglandin E2 concentration. Results: There was an improvement in all clinical periodontal parameters evaluated in both groups as well as the amount of gingival crevicular fluid. It occurred more significant decrease (p<0,05) in HbA1c and PGE2 expression in group test 1, after 6 months. Conclusion: The basic periodontal treatment was more effective for glycemic control in patients with type 1 diabetes mellitus / A periodontite é frequentemente associada com diabetes mellitus (DM) e pode ser considerada uma das complicações crônicas da doença. Crescentes evidências apontam que a doença periodontal (DP) tem um efeito adverso sobre o controle glicêmico e uma participação ativa na fisiopatologia das complicações relacionadas ao DM, tanto no diabetes mellitus tipo 1(DM1) quanto no diabetes mellitus tipo 2 (DM2). Objetivo: Comparar a resposta do tratamento periodontal básico em pacientes portadores de diabetes mellitus tipo 1 e tipo 2. Metodologia: Foram selecionados 70 pacientes com periodontite, estes foram divididos em três grupos: Grupo controle (pacientes sistemicamente saudáveis); Grupo teste 1 (pacientes portadores de diabetes mellitus tipo 1); Grupo teste 2 (pacientes portadores de diabetes mellitus tipo 2). Os grupos receberam tratamento periodontal básico, após exame clínico. As análises foram realizadas aos 0, 3 e 6 meses, incluindo parâmetros clínicos periodontais e a quantidade de fluido crevicular gengival (GCF). Foram dosadas a hemoglobina glicada (HbA1c) e a concentração de prostaglandina E2 (PGE2) no GCF. Resultados: Houve melhora de todos os parâmetros clínicos periodontais avaliados em todos os grupos, bem como na quantidade de fluido crevicular gengival. Ocorreu diminuição mais expressiva (p<0,05) da HbA1c e da expressão de PGE2 no grupo teste 1, após 6 meses. Conclusão: O tratamento periodontal básico mostrou-se mais eficaz para o controle glicêmico dos pacientes portadores de diabetes mellitus tipo 1.

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