In many musical cultures, people synchronise their bodies to the rhythmic patterns of the music, and such embodied engagements are one of the most overtly enjoyable forms of musical appreciation. However, the ways in which rhythmic structure, body-movement and pleasure are related remains unclear. The present thesis directs a broadly psychological, yet multi-methodological and interdisciplinary, approach towards this relationship, centring on the rhythmic structure of syncopation in groove-based funk music. Through perceptual experiments, computational modelling, rating surveys, neuroimaging and motion-capture recording, syncopation was found to relate, in primarily negatively linear and inverted U-shaped ways, to finger-tapping performance, perceptions of stability, subjective desire to move and feelings of pleasure, neural activity in motor and reward areas, and force, synchrony and periodicity in body-movements. These relationships also depended on individuals’ musical training, dancing experience and groove familiarity. Ecological and embodied theories of perception and a phenomenology of groove provide a backdrop to the empirical findings, on the basis of which it is suggested that the different relationships between syncopation in groove and perceptual, subjective, neural and corporeal attributes interact in reciprocal ways. It is proposed that syncopation invites the body to physically enact the musical structure and directly participate in the rhythms of groove, due to the perceptual tension and ‘open spaces’ afforded by the perception of metric events in syncopation. In groove, body, mind and music extend into each other and this distributed musical process has affective significance. Since the physical pleasures of dancing to music are such a historically and culturally ubiquitous phenomenon, the empirical findings and theoretical proposals of this thesis make significant contributions towards a much-needed coupling of affective and embodied theories of music.

Pathological gambling is a maladaptive behaviour associated with diminished self-control over persistent compulsive gambling behaviour despite negative consequences. A significant revision to the clinical perspective of pathological gambling is underway, and the disorder will likely be recognized as a behavioural addiction in the fifth edition of Diagnostic and Statistical Manual of Mental Disorders. However, the neurobiological, cognitive and behavioural processes that drive a ‘behavioural addiction’ are unclear. A series of five studies were conducted to investigate cognitive mechanisms associated with neural and behavioural substrates of addictive processes in disordered gambling. Studies 1 through 3 investigated neurobiological correlates of addiction in individuals with pathological gambling as compared to individuals with cocaine dependence, and as compared to non-addicted healthy controls. Study 1 investigated brain activity associated with anticipatory and consummatory reward processing during slot-machine gambling. Study 2 investigated executive control processes by examining functional brain networks associated with loss-chasing behaviour. Study 3 employed voxel-based morphometry (VBM) to explore alterations in grey-matter volumes in individuals with addictive disorders. Studies 4 and 5 investigated the behavioural substrates of addiction in regular gamblers utilizing emerging and novel research techniques. Study 4 examined continuous hand motion trajectories to explore approach biases and implicit processing. Study 5 employed an adaptive testing methodology to explore the influence of gaming machine preferences on cognitive processes and gambling behaviour. Research identified neurobiological and behavioural substrates of gambling-related beliefs and biases that indicate significant contributions of cognitive mechanisms to the development and persistence of a behavioural addiction. Results suggest addictive disorders may share some common features of anticipatory reward processing and brain structure (Studies 1 and 3), while neural signals associated losing outcomes and decision-making during gambling may be specific to disordered gambling (Studies 1 and 2). Furthermore, cognitive distortions in regular gamblers may influence reinforcement and executive control processes (Study 4), and individual preferences for gaming speed may influence cognitions and behaviour during machine gambling. As additional psychological disorders are being considered for classification as behavioural addictions, and clinicians will be faced with the challenges of treating individuals with these non-substance-related addictive disorders, a better understanding of behavioural addictions, through the study of disordered gambling, will be essential under the new diagnostic framework.

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Sleep is a complex process: the timing of sleep is regulated by two systems (the sleep homeostat and the circadian clock) and there are many potential functions of sleep. The aim of this thesis was to investigate: the impact of light on the regulation of sleep timing (study 1) and the role of sleep in emotional processing (study 2). Study 1 used natural variations in environmental light levels at different geographical locations, to examine the influence of daily light irradiance on sleep timing and chronotype using the Munich chronotype questionnaire (MCTQ). 6443 students were included in this study from six universities from the northern and southern hemispheres. Students in southern hemisphere cities had earlier sleep timings than those in the northern cities. Daily irradiance was higher in the southern hemisphere cities. The amount of time spent outside, age and sex, but not daily irradiance, influenced sleep timings. Study 2 explored the impact of an analogue traumatic event (trauma film) in students who were either sleep deprived or not sleep deprived on intrusive memories ("flashbacks"), sleep physiology and the impact of an increased risk of a mood disorder on this relationship. In this study the sleep deprived participants (n=19) reported fewer intrusive memories to the trauma film than those not sleep deprived (n=22). A change in sleep physiology was observed in the first sleep period following the trauma film, which was more pronounced in the sleep deprived group: increased levels of arousal, REM density and activity in the occipital region. Only three participants at-risk of a mood disorder completed study 2: their data are presented as case studies. In conclusion this research has demonstrated that differences in sleep timings exist between cities in the southern and northern hemispheres and has confirmed that many factors can influence sleep timing. It has also been demonstrated that following a highly emotional event not sleeping may have a beneficial effect, which has implications for the treatment of people after trauma.

The aim of this thesis was to understand the function of the frontal lobes during different types of decisions thusfar mostly neglected in cognitive neuroscience. Namely, I sought to understand how decisions are made when comparisons are not about a simple set of concrete options presented, but rather require a comparison with one specific encounter and a sense of the value of the current environment <b>(Chapter 2-3)</b>. Additionally, I wanted to understand how decisions between concrete options can be contextualized by the current environment to allow considerations about changing environmental constraints to factor into the decision making process <b>(Chapter 4-5)</b>. At last, I wanted to test how the potential for future behaviours within an environment has an effect on peoples decisions <b>(Chapter 6)</b>. In other words, how do people construct prospective value when it requires a sense of own future behaviours? All this work was informed by concepts and models originating from optimal foraging theory, which seeks to understand animal behaviours using computational models for different ecological types of choices. Thus, this thesis offers a perspective on the neural mechanisms underlying human decision making capacities that relates them to common problems faced by animals and presumably humans in ecological environments <b>(Chapter 1 and 7)</b>. As optimal foraging theory assumes that solving these problems efficiently is highly relevant for survival, it is possible that neural structures evolved in ways to particularly accommodate for the solution of those problems. Therefore, different prefrontal structures might be dedicated to unique ways of solving ecological kinds of decision problems. My thesis as a whole gives some evidence for such a perspective, as dACC and vmPFC were repeatedly identified as constituting unique systems for evaluation according to different reference frames. Their competition within a wider network of areas appeared to ultimately drive decisions under changing contexts. In the future, a better understanding of those changing interactions between these prefrontal areas which generate more complex and adaptive behaviours, will be crucial for understanding more natural choice behaviours. For this temporally resolved neural measurements as well as causal interference will be essential.

The role of the primate frontopolar cortex (FPC) has been investigated using human neuroimaging, lesion and disruption techniques. The results of these investigations have led to a variety of theories regarding the function of this region. It has been linked to the formation of task sets, the performance of multiple tasks, reasoning, context-specific memory (including episodic memory, prospective memory and source memory), attention to internally or externally generated information, mentalising and decision-making. It has not previously been possible to study this area using animal lesion techniques. Here, behavioural experiments conducted using non-human primates (rhesus macaque monkeys) who have received lesions to the frontal pole investigate the contribution of this region to context-specific memory, decision-making and social cognition. Functional magnetic resonance imaging (fMRI) is used to investigate changes in functional network connectivity which occur after lesions to this region. A long-lasting impairment is observed in contextual memory judgements (specifically, how recently a stimulus was encountered) after lesions to the frontal pole. An analysis of the influence of the outcomes of previous choices on behaviour on an analogue to the Wisconsin Card Sorting Test (WCST) indicate that monkeys with lesions to area 10 may be less influenced by the outcomes of an extended history of rewards than control animals. Long-lasting widespread disruption to functional networks after lesions to this region indicate that indirect anatomical connections from this region to posterior areas play a crucial role in the normal functioning of posterior networks.

Experience of the built-environment is said to be dependent on visual perception and the physical properties of space. Scene and environmental preference research suggests that particular visual features greatly influence one’s response to their environment. Typically, environments which are informative and allow an individual to gain further knowledge about their surroundings are preferred. Although, such findings could be applied to the design process it is first necessary to develop a way in which to accurately and objectively describe the visual properties within an environment. Recently it has been proposed that isovist analysis could be employed to describe built-environments. In two experiments we examined whether or not isovist analysis can capture experience of real-world environments. In Experiment one we demonstrated that isovist analysis can be employed to describe experience of environment within a controlled, laboratory environment. In Experiment two we employed some of the methods of post-occupancy analysis to examine the robustness of the isovist approach and whether it would capture experience of a complex, real-world environment. The results of Experiment two suggest that isovist analysis could capture certain experiences, such as spaciousness, but failed to capture other responses. Regression analysis suggests that a large number of variables predicted experience, including previous experience with the building and the presence of other individuals. These findings suggest that experience of real-world, complex environments cannot be captured by the visual properties alone, but also highlight some of the other factors, such as presence of others and previous experiences may influence experience of built settings. Implications for the design processes are described.

The direction in which another is looking at triggers a spontaneous orienting of attention towards gaze direction in the viewer. However, whether the facial expression displayed by the gazing individual modulates this attention orienting is unclear. In this thesis, the modulation of gaze-oriented attention with facial expressions was explored in non-anxious individuals at the behavioral level and at the neural level using Event-Related Potentials (ERP). In the gaze-cueing paradigm used, a dynamic face cue averting gaze and expressing an emotion was presented, followed by a lateral, to-be-localized target. At the behavioral level, a faster response to targets appearing at the gazed-at location (congruent targets) than to targets appearing opposite to the gazed-at location (incongruent targets) was observed (Chapters 3-5). This so-called Gaze Orienting Effect (GOE) was enhanced with fearful, angry and surprised expressions relative to neutral and happy expressions and was driven by emotional differences in response speed to congruent targets (Chapters 3-5). These effects could not be attributed to better discrimination of those emotions when presented with an averted gaze (Chapter 2). These results confirm the impact of fear and surprise on gaze-oriented attention in non-anxious individuals and demonstrate, for the first time, a similar impact for angry expressions. All the emotions enhancing the GOE signal an evolutionary relevant stimulus in the periphery, are threat-related and carry a negative valence, which suggests that one of these attributes (or all combined) is driving the emotional modulation of gaze-oriented attention (surprise is treated like fear in the context of fearful expressions). In Chapter 4, the effect of the dynamic cue sequence on these GOE modulations was investigated. An emotional modulation of the GOE was found only when the gaze shift preceded the emotional expression, but not when the emotion was expressed before gaze shift or when expression and gaze shift were simultaneous. These results highlight the importance of using a sequence closer to real life situations (we usually orient attention before reacting to an object in the environment) in studying the modulation of the GOE with emotions. At the neural level, we investigated the ERPs associated with gaze-oriented attention at target presentation and at cue presentation (Chapters 3 and 5). Confirming previous reports, the amplitude of a target-triggered P1 ERP component was larger in the congruent than in the incongruent condition, reflecting enhanced processing of gaze-congruent targets. In addition, cue-triggered ERPs previously observed in response to arrow cues, were investigated. An Early Directing Attention Negativity (EDAN) and an Anterior Directing Attention Negativity (ADAN) were found, indexing respectively attention-orienting to the cued location and maintenance of attention at the cued location. This is the first study to report both EDAN and ADAN components in response to gaze cues. These results show clear markers of attention orienting by gaze at the neural level, during both cue and target processing. Neither EDAN nor ADAN was modulated by emotion. The congruency effect on P1 was enhanced for fearful, surprised and happy faces compared to neutral faces in Chapter 3 but no differences between the emotions were found in Chapter 5. Thus, the emotional modulation of the brain processes involved in gaze-oriented attention is very weak and protracted or occurs mainly between target onset and response to target. The relationships between participants’ autistic traits and their emotional modulation of gaze-oriented attention were also investigated. Results showed a negative correlation with the GOE to happy upright faces and with the P1 congruency effect, which suggests that individuals with more severe autistic traits are less sensitive to the impact of social emotions like joy. The implication of these results for attention orienting in general and for individuals with Autism Spectrum Disorder is discussed. Together, the findings reported in this thesis clarify the behavioral and neural processes involved in gaze oriented attention and its modulation by facial expression in addition to demonstrating a relationship between gaze oriented attention, its modulation with social emotions and autistic traits.

Right parietal lesions often lead to neglect, in which patients fail to attend to leftward stimuli. Recent models of neglect suggest that, in addition to attentional impairments, patients demonstrate impairments of spatial remapping and/or spatial working memory (SWM). Although spatial remapping could be considered a kind of spatial memory process itself (i.e., updating remembered locations based on anticipated saccade outcomes), the two processes operate on very different time scales (milliseconds versus seconds). In the present study, the influence of saccadic and spatial remapping on SWM was examined in healthy individuals. An initial control condition, in which participants had to respond to a probe stimulus (i.e., “is the probe in the location previously occupied by the target?”) following a 1500 ms delay, was contrasted with conditions in which the fixation point moved (left, right, up, or down) at the onset of the delay. In a second version of the task, participants made covert shifts of attention at delay onset requiring covert spatial, rather than saccadic, remapping. In both tasks SWM performance was best when no remapping was required. Decrements in SWM were largest overall in the spatial remapping task, whereas for both saccadic and spatial remapping, a consistent cost was observed for remapping the target array into right visual space. Results are discussed in terms of hemispheric biases in attention and differences in performance for peripersonal versus extrapersonal space.

In this dissertation, three experiments were conducted that examined the influence of task demands on manual asymmetries for the performance of reaching movements to tools. In all three experiments, the difference between the hands (in terms of preference for Experiment 1 and performance for Experiments 2 and 3) was studied in response to varying task demands for grasping movements to tools. In the first experiment, 82 right-handed and 60 left-handed university students performed reaching movements to tools and dowels at five positions within working space. Differences in the reaching patterns of the left and right hands to the tools and dowels were examined, as well as the effect of task demands (lift, use) and type of object (tool, dowel) on the reaching patterns. Dowels were used in order to examine if participants would treat a neutral object as if it were a tool in terms of their reaching patterns in working space. Results confirmed and extended prior research on the influence of task demands on reaching patterns within working space. Overall, there were more similarities in the general reaching patterns of left- and right-handed participants than differences. However key differences between the handedness groups emerged in the treatment of the dowel and the frequency of switches (reaching to lift the object with the non-preferred hand and transferring it to the preferred hand to use). Results also showed that tools enjoy a privileged association with the preferred hand, and that the intent of the movement has a very real goal on movement planning. The first experiment examined patterns of hand use across working space in response to differing task demands. In the next experiments performance differences between the hands in terms of movement planning and initiation were examined through the use of reaction time and movement time. In these experiments, reaction time represented the time from the presentation of a go signal to when the participant first lifted their hand, and movement time was the time between lifting the hand to lifting a tool off a sensor. Movement time represented the time to pick up the tool, and did not include the time to use the tool to perform a particular task and complete the reaching movement. In the second experiment, reaction time and movement time to tools placed at the midline position were examined under varying degrees of advance information using a precue paradigm. Three precue conditions were used which presented advance information on the hand to use to perform the movement (left or right) and/or the task (lift, use, or pantomime) to be performed: (1) both hand and task were cued in advance (Both precue); (2) task only was cued in advance (Task precue); and (3) neither hand nor task were cued in advance (No precue). Twenty-four right-handed university students performed reaching movements to tools under the three different precue conditions. The results of Experiment 2 showed that reaction time was sensitive to the amount of advance information presented in the precue. For reaction time manual asymmetries were observed in one condition only – a right hand advantage was present in the No precue condition. In contrast manual asymmetries in favor of the right hand were clearly observed with the movement time results. Experiment 2 was the first experiment reported in the literature to systematically examine reaction time for reaching and grasping movements to tools. In order to further explore these results, in Experiment 3 a fourth precue condition (in which the hand to be used was cued in advance; the Hand precue) was added to the precue paradigm used in Experiment 2. An additional variable called replacement time, which represented the time spent interacting with the tool, was also examined. Forty-two right-handed university students participated in Experiment 3. The results of Experiment 3 largely replicated the findings of Experiment 2, and indicated that both the amount and type of precue information had an effect on reaction time. The addition of the Hand precue condition suggested that having advance knowledge of the hand to be used to perform the task was of greater importance for movement planning than was advance knowledge of the task to be performed. Regarding the movement time results, Experiment 3 was one of the first experiments to show the influence of task demands on the magnitude of manual asymmetries. The lack of differences between the hands for the replacement time results also suggested that the initial execution of the movement (represented by movement time) was most sensitive to manual asymmetries. Overall, these experiments provided further insight into manual asymmetries for the performance of reaching movements, and illustrated how simple manipulations of task demands led to differences between the hands in measures of both preference and performance when interacting with tools.