Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2015-12-07T19:57:50Z No. of bitstreams: 1 AngeloJosePimentelDeAzevedo_DISSERT.pdf: 1068827 bytes, checksum: f639b14a024a9d17a9fc9313815fe2f2 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2015-12-10T19:56:55Z (GMT) No. of bitstreams: 1 AngeloJosePimentelDeAzevedo_DISSERT.pdf: 1068827 bytes, checksum: f639b14a024a9d17a9fc9313815fe2f2 (MD5) / Made available in DSpace on 2015-12-10T19:56:55Z (GMT). No. of bitstreams: 1 AngeloJosePimentelDeAzevedo_DISSERT.pdf: 1068827 bytes, checksum: f639b14a024a9d17a9fc9313815fe2f2 (MD5) Previous issue date: 2014-08-29 / Introdu??o: Os benzodiazep?nicos (BDZs) alcan?aram grande popularidade dentre os membros da classe m?dica e na popula??o como indica??o para sintomatologia de ansiedade, comum na sociedade moderna. Os fatores psicossociais, econ?micos e culturais, parecem estar associados aos crescentes preju?zos ? sa?de mental dos indiv?duos e ao consumo desses medicamentos. Objetivo: o presente trabalho busca a compreens?o de como se relaciona, na capital do Distrito Federal e demais capitais estaduais brasileiras, o uso/consumo dessas drogas - atrav?s de dados agregados agora mais confi?veis - com caracter?sticas demogr?ficas, epidemiol?gicas, econ?micas e, sobretudo sociais. Metodologia: estudo ecol?gico tendo como unidade amostral as capitais brasileiras e fonte de dados o Censo demogr?fico 2010 e informa??es do IBGE, DATASUS e da ANVISA referentes aos anos entre 2007 e 2010. Foi utilizada regress?o linear m?ltipla como m?todo de an?lise. Resultados: A an?lise descritiva resultou no conhecimento que Salvador ? a capital que mais consumiu esses medicamentos com 10,64 DDD por mil habitantes por dia e que dentre eles o Alprazolam ? o mais dispensado pelas farm?cias e drogarias particulares 2,63 DDD/1000hab/dia das capitais brasileira. Ap?s an?lise de regress?o linear o modelo apenas com percentual de idosos foi respons?vel por explicar 51,3% da varia??o no consumo dos medicamentos. / This work aims to analyze the distribution of anxiolytics and their frequency of consumption in the period of 2010 to 2012, on the Federal District and at other Brazilian cities, as well as evaluating the correlation between such consumption and its demographic, epidemiological, economic and social characteristics for each region of this study. Into the analysis, it was observed that social, economic and cultural factors seem to influence the over-consumption of these drugs in many countries. Based on this, the benzodiazepines (BDZs) have achieved great popularity among members of the medical community and among the general population, mainly because of its safety and effectiveness in controlling symptoms of anxiety, insomnia and convulsions. Concerning the methodology of this work, an ecological study was performed having as sampling Brazilian capitals and as data source the 2010 Population Census, as well as information from IBGE, DATASUS and ANVISA. Still in the case of the methodological procedure, a multiple linear regression was used. Through descriptive analysis, it was demonstrated that the Northern region has the lowest average on consumption of these drugs (being 0.24 DHD in Manaus); meanwhile in the capitals of the Southeast, higher means were identified (reaching 7.29 DHD in Belo Horizonte), with a national average of 3.04 DHD. Among the drugs analyzed, it was found that Alprazolam is the most dispensed by pharmacies and private drugstores, averaging 2.00 DHD for Brazilian capitals. A an?lise de regress?o linear m?ltipla mostrou que 76% da varia??o no consumo foi explicada pela varia??o da densidade populacional (? = 0,310 p = 0,045) e pela percentagem de m?dicos (? = 0,507 p = 0,016). Therefore, it was concluded that the consumption of anxiolytics of short half-life has been increasing over the years, mainly in the cities of greater population density and with the highest concentration of doctors