Spelling suggestions: "subject:"blindness."" "subject:"bllindness.""
71 |
Chemical and photic damage to DNA as pathogenetic mechanisms in the aetiology of macular degeneration of the eyePatton, William P. January 1998 (has links)
No description available.
|
72 |
Implicit and explicit capture of attention: what it takes to be noticedvan Rij, Nathan Gordon January 2007 (has links)
Two Inattentional Blindness type experiments involving 446 participants were performed in order to examine how unexpected objects are noticed. Perception of these unexpected objects was measured using explicit and implicit measurements. Despite initial difficulty in determining implicit perception, results showed a dissociation between implicit measurements and explicit measurements, providing strong evidence for unconscious processing. Research into attention capture often emphasizes the role of either expectations or stimulus properties in attention capture; the current research examines both. Critical objects presented were either of a colour that participants were familiar with, or of a new colour. The different patterns of results for these two categories of objects provide evidence for two separate mechanisms of attention capture: a parallel process driven by the features of objects, and a serial process, driven by the intentions of the observer. Predications of the recent theoretical work produced by Most, Scholl, Clifford & Simons, (2005) are examined, and support is obtained for their theoretical formulation.
|
73 |
Diabetes-related blindness : studies of self-management, power, empowerment and health /Leksell, Janeth, January 2005 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 5 uppsatser.
|
74 |
Assessment of orientation and mobility among the blind in the Bangkok Metropolitan area /Fujita, Satoshi, Kanittha Chamroonsawasdi, January 2004 (has links) (PDF)
Thesis (M.P.H.M. (Primary Health Care Management))--Mahidol University, 2004.
|
75 |
Relationship between quality of familial interactions and acquisition of a "Theory of Mind" in blind children /Roch-Levecq, Anne-Catherine. January 2001 (has links)
Thesis (Ph. D.)--University of California, San Diego, 2001. / Vita. Includes bibliographical references (leaves 126-137).
|
76 |
Proprioception coding and retention ability in visually impaired and non-visually impaired childrenCosta, Rita Maria Adler Gomes da. January 2002 (has links)
Thesis (M.S.)--Indiana University, 2002. / Includes bibliographical references (leaves 77-84).
|
77 |
Towards a grammar of theatrical blindnessWard, Marchella January 2018 (has links)
Since the fifth century, the theatre has been a place for seeing. In spite of this, blind figures repeatedly appear on the stage, from Oedipus, Polymestor, Tiresias and the Cyclops to Shakespeare's Gloucester, Beckett's Hamm, Friel's Molly Sweeney and Kane's Ian. These blind characters have an important role to play in articulating the task of the spectator, both in their aural and imaginative construction of the fictional world in pre-naturalistic theatre, and also in their ability to see through the dramatic illusion in later drama. These scenes of blindness and blinding also have consequences for reception studies, since the relationship between them is not straightforwardly a textual reception history. Instead, these blind characters and the scenes in which they appear are read as what Deleuze and Guattari term an 'assemblage': a heterogenous multiplicity that is produced at the moment of reading / watching with reference to other scenes of blindness and blinding. This thesis sketches out a grammar for such an assemblage, and each chapter focuses on a rule in this grammar. When read as part of an assemblage of blindness, blind characters always have a special relationship with death (Chapter 2), showcase their own performance (Chapter 3), undermine the fictional setting that has been established onstage (Chapter 4), have access to a kind of superhuman knowledge (Chapter 5) and alter the position of their spectators (Chapter 6). Each chapter is structured around a particular moment when the theatre's interest in blind characters resurges, as a response to changes in the social, cultural or scientific understanding of vision and visual impairment. In each chapter, the grammar that is outlined in Chapter 1 with reference to ancient plays returns to the fore, but is refracted through the historical period back on to the grammar of the assemblage.
|
78 |
An investigation of methods for enriching a print text for use with visually-handicapped studentsGrant, Barbara F. January 1963 (has links)
Thesis (Ed.M.)--Boston University
|
79 |
Experimental vaccination for onchocerciasis and the identification of early markers of protective immunityDuprez, Jessica Anais Sybille January 2018 (has links)
Onchocerciasis, caused by Onchocerca volvulus remains a major public health and socio-economic problem across the tropics, despite years of mass drug administration (MDA) with Ivermectin to reduce disease burden. Through modelling, it has been shown that elimination cannot be achieved with MDA alone and additional tools are needed, such as vaccination, which remains the most cost-effective tool for long-term disease control. The feasibility behind vaccination against O. volvulus can be demonstrated in the Litomosoides sigmodontis mouse model, which shows that vaccine induced protection can be achieved with immunisation using irradiated L3, the infective stage of L. sigmodontis and with microfilariae (Mf), the transmission stage of the parasite. There is further evidence of protective immunity in humans, with individuals living in endemic areas that show no signs of infection despite being exposed to the parasite (endemic normal). The protective efficacy of promising vaccine candidates were evaluated using an immunisation time course in the L. sigmodontis model, using either DNA plasmid or peptide vaccines. In immunisation experiments in L. sigmodontis, Mf numbers are used as a measure of protection and marks the end of an immunisation time course. However, when changes in gene expression were measured at the end of an immunisation time course, in attempts to identify gene signatures that could be used as markers of protection (correlates of protection) in the blood, no gene signatures were found to be associated with protection. This suggest that at the end of an immunisation time course, when protection is measured (change in Mf numbers), it is too late in infection to measure changes in immune pathways being triggered. Changes in gene expression were therefore measured in blood samples collected throughout an immunisation time course in the L. sigmodontis model, in order to identify the time point in an immunisation experiment which are the most indicative of protection. Two independent immunisation time courses were used, either using irradiated L3 or Mf as vaccine against L. sigmodontis, as these elicit the greatest protection. This generated a large high dimensional dataset, that was too large and complex for a differential fold-change analysis. Therefore, an analysis pipeline was created using machine learning algorithms, to detect changes in gene expression throughout the time courses to detect markers of protection. The 6 hour time point following immunisation showed the greatest change in gene expression, with the analysis pipeline identifying known pathways associated with vaccine-induced immunity. The pipeline was applied to gene expression data from human samples obtained from individuals living in endemic areas who were either infected with O. volvulus or endemic normal (naturally protected), this was to identify pathways associated with protective immunity in humans. When comparing vaccine induced immunity seen in mice and natural protective immunity in humans there was some overlap in pathways being triggered, suggesting that similar pathways are needed for protection and that if a vaccine can trigger the right pathways in mice, it is likely to be effective in humans. Overall the machine learning analysis of the gene expression data, not only shows that it is feasible to measure change in gene expression in blood during filarial infections, but that during an immunisation time course it is the early time points following immunisation that are the most predictive of vaccine efficacy (protection outcome). One of the vaccine candidates, cysteine protease inhibitor-2 (CPI), is a known immuno-modulator that inhibits MHC-II antigen presentation on antigen presenting cells such as dendritic cells (DC). This candidate has consistently been shown to induce protection if its immuno-modulatory active site was modified. In in vitro studies, it was shown that modification of the active site of CPI rescues antigen presentation in DC. This shows the importance of DC activation before the onset of infection, demonstrating the importance of triggering protective responses early in infection, and provides insight on how one of the vaccine candidates achieves protection.
|
80 |
Blindness - O ensaio sobre cegueira de Fernando Meirelles: A visão do realizadorSILVA, F. P. 22 August 2014 (has links)
Made available in DSpace on 2016-08-29T14:11:30Z (GMT). No. of bitstreams: 1
tese_8132_Fabiane Pimentel Silva.pdf: 789149 bytes, checksum: 5dddc5c55ab297143a4ae87b4d9d8b31 (MD5)
Previous issue date: 2014-08-22 / Em 2008 o diretor Fernando Meirelles apresentou ao público o filme Blindness (Cegueira), que tem o título de Ensaio sobre a cegueira, no Brasil, foi uma realização a muito pretendida pelo cineasta brasileiro. Para realizar o filme, Meirelles recebeu o roteiro já pronto do produtor canadense Niv Fichman após ser convidado em 2006 a realizar a versão para o cinema. O cineasta considerou o convite para dirigir o filme, além de uma surpresa, uma coincidência assustadora, pois ele já havia tentado comprar os direitos do romance alguns anos antes na intenção de filmar a história, mas o autor português recusou-se a tal proposta. Desta vez após insistência de Fichman, Saramago autoriza a filmagem do romance e acompanha o desenvolvimento do trabalho de Meirelles. O filme teve o roteiro adaptado por Don McKellar, e é uma coprodução independente Canadá, Brasil, Japão. Além do roteiro, o diretor utilizou o texto do romance para o trabalho com os atores em cena, propondo que todos lessem o livro incluindo a equipe técnica. No filme, Meirelles também se preocupou em considerar as relações iconográficas ligadas às metáforas visuais tão características ao texto de Saramago, e mantidas no audiovisual. O objetivo da pesquisa centrou-se no processo de criação e direção do filme a partir da visão do realizador.
|
Page generated in 0.0309 seconds