- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 151 to 160 of 618 (0.013 seconds)| 151 |
Chromosome behaviour in plant breedingMoss, J. P. January 1965 (has links)
No description available.
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| 152 |
A study of shear-force microscopy and its application to liquid-crystal and biological systemsBrereton, Luke James January 1998 (has links)
No description available.
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| 153 |
NUCLEOLUS ORGANIZERS IN CHROMOSOMES OF THE DOMESTIC DOG, CANIS FAMILIARIS.Hutchison, Holly Marie. January 1982 (has links)
No description available.
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| 154 |
The induction and production of chromosomal aberrations by restriction endonucleasesHarvey, Alison Nichola January 1997 (has links)
No description available.
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| 155 |
A cDNA selection approach to isolate Y-linked genes expressed in testisMakrinou, Eleni January 2000 (has links)
No description available.
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| 156 |
Repetitive DNA in aphids : its nature, chromosomal distribution and evolutionary significanceSpence, Jennifer M. January 1999 (has links)
No description available.
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| 157 |
Characterisation of Burkholderia cepacia from clinical and environmental originsWigley, Paul January 1999 (has links)
No description available.
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| 158 |
Partition proteins of bacterial genomesBignell, Colin Richard January 1999 (has links)
No description available.
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| 159 |
Identification and characterisation of genes involved in cell division and sporulation in Bacillus subtilisThomaides, Helena B. January 1999 (has links)
No description available.
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| 160 |
Identification and analysis of chromosome-organising-clamp sites in the budding yeast S. cerevisiaeBotsios, Sotirios January 2010 (has links)
The three-dimensional spatial architecture of chromosomes is integrally connected to chromatin function. Budding yeast telomeres cluster at the nuclear periphery, the ribosomal genes are localised to the nucleolus, tRNA genes may also tend to localise to the nucleolus or centromeres, while the later cluster near the spindle pole body. Recently, in the fission yeast Schizosaccharomyces pombe, a novel role has been revealed for the RNA polymerase III transcriptional apparatus, and TFIIIC in particular, in chromosome spatial organisation and boundary function. In this project, I investigate whether Saccharomyces cerevisiae Extra TFIIIC (ETC) sites, which bind the TFIIIC transcription factor but do not recruit RNA polymerase III, act to position chromosomal domains. I show that six of the eight known S. cerevisiae ETC sites localise predominantly at the nuclear periphery. An ETC site retains its tethering function when moved to a new chromosomal location. TFIIIC binding is necessary for peripheral localisation, since deleting the TFIIIC binding consensus ablates ETC site peripheral positioning. I find that any of the six TFIIIC subunits can drive peripheral tethering, suggesting that the TFIIIC complex is central to the positioning mechanism. Interestingly, anchoring of ETC sites to the nuclear periphery also requires Mps3, a Sad1-UNC-84 domain protein that spans the inner nuclear membrane. Moreover, I show that the mechanism of ETC site peripheral tethering requires chromatin remodelling proteins, and in particular Histone 3 - Lysine 56 (H3K56) acetylation. Finally, I investigate the biological function of ETC sites and examine the connection between this biological function and their ability to anchor at the nuclear periphery. In summary, TFIIIC and Mps3 together position a new class of genomic loci crucial for correct spatial organisation of S. cerevisiae chromosomes.
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