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Accuracy and Enhancement of the Lattice Boltzmann Method for Application to a Cell-Polymer Bioreactor SystemDeladisma, Marnico David 11 April 2006 (has links)
Articular cartilage has a limited ability to heal due to its avascular, aneural, and alymphatic nature. Currently, there is a need for alternative therapies for diseases that affect articular cartilage such as osteoarthritis. Recently, it has been shown that tissue constructs, which resemble cartilage in structure and function, can be cultured in vitro in a cell-polymer bioreactor system. Bioreactors provide a three dimensional environment that promotes cell proliferation and matrix production. The primary objective of this study is to accurately simulate fluid mechanics using the lattice Boltzmann method for application to a cell-polymer bioreactor system.
Lattice Boltzmann (LB) is a flexible computation technique that will allow for the simulation of a moving construct under various bioreactor conditions. The method predicts macroscopic hydrodynamics by considering virtual particle interactions. Derived from the Lattice Gas Automata, lattice Boltzmann allows for mass transfer, complex geometries, and particle dynamics. A primary goal is to characterize the accuracy of the LB implementation and eventually the shear stresses felt by a tissue construct in this dynamic environment. This information is important since recent studies show that chondrocytic function may depend on the mechanical stimuli produced by fluid flow. Hence, shear stress may affect the final mechanical properties of tissue constructs. In this study, numerical simulations are done first in 2D and then extended to 3D to test the LB implementation. Simulations of the rotating wall vessel (RWV) bioreactor are then undertaken. The results are benchmarked against computations done with a commercial CFD package, FLUENT, and compared with analytic solutions and experimental data.
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Finite Element Simulation of the Atomization of Liquid Membrane in Gene GunLin, Wei-ting 14 August 2012 (has links)
In recent years, with advances in medical treatment, the demand of medical beauty market has increased year by year. With the continuous innovation of nanotechnology, medical technology with nanometer level is becoming the one of the most important issue of the development of medical biotechnology in recent years. In order to make the products effective, the products have to be transported into the human skin. In traditional medical treatments, the devices of contacting type or invading type were adopted, and might cause some infected problems. To avoid these situations, some medical companies have developing the non-contact type device¡Ð gene gun. This device use nitrogen as motive force to atomize the thin film of the injection products, then delivering these products to derma.
This research utilizes computational fluid dynamics software to build the FEM simulation model of Venturi tube inside of a gene gun. Then, analyzing the speed and atomization of fluid which inside or outside of Venturi tube. A FEM simulated mechanism for the atomization of multiphase flow was constructed in this research successfully. The effects of variations of some geometric parameters of Venturi tube on the atomization of thin film were studied also. The obtained results can shorten cost and time in relevant development.
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Investigation of Swirl Flows Applied to the Oil and Gas IndustryRavuri Venkata Krish, Meher Surendra 16 January 2010 (has links)
Understanding how swirl flows can be applied to processes in the oil and gas industry and how problems might hinder them, are the focus of this thesis. Three application areas were identified: wet gas metering, liquid loading in gas wells and erosion at pipe bends due to sand transport. For all three areas, Computational Fluid Dynamics (CFD) simulations were performed. Where available, experimental data were used to validate the CFD results. As a part of this project, a new test loop was conceived for the investigation of sand erosion in pipes.
The results obtained from CFD simulations of two-phase (air-water) flow through a pipe with a swirl-inducing device show that generating swirl flow leads to separation of the phases and creates distinct flow patterns within the pipe. This effect can be used in each of the three application areas of interest.
For the wet gas metering application, a chart was generated, which suggests the location of maximum liquid deposition downstream of the swirling device used in the ANUMET meter. This will allow taking pressure and phase fraction measurements (from which the liquid flow rate can be determined) where they are most representative of the flow pattern assumed for the ANUMET calculation algorithms.
For the liquid loading application, which was taken as an upscaling of the dimensions investigated for the wet gas metering application, the main focus was on the liquid hold-up. This parameter is defined as the ratio of the flowing area occupied by liquid to the total area. Results obtained with CFD simulations showed that as the water rate increases, the liquid hold-up increases, implying a more effective liquid removal. Thus, it was concluded that the introduction of a swirler can help unload liquid from a gas well, although no investigation was carried out on the persistance of the swirl motion downstream of the device.
For the third and final application, the erosion at pipe bends due to sand transport, the main focus was to check the erosion rate on the pipe wall with and without the introduction of a swirler. The erosion rate was predicted by CFD simulations. The flow that was investigated consisted of a liquid phase with solid particles suspended in it. The CFD results showed a significant reduction in erosion rate at the pipe walls when the swirler was introduced, which could translate into an extended working life for the pipe. An extensive literature review performed on this topic, complemented by the CFD simulations, showed the need for a dedicated multiphase test loop for the investigation of sand erosion in horizontal pipes and at bends. The design of a facility of this type is included in this thesis.
The results obtained with this work are very encouraging and provide a broad perspective of applications of swirl flows and CFD for the oil and gas industry.
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Computational fluid dynamics (CFD) simulations of aerosol in a u-shaped steam generator tubeLongmire, Pamela 15 May 2009 (has links)
To quantify primary side aerosol retention, an Eulerian/Lagrangian approach was
used to investigate aerosol transport in a compressible, turbulent, adiabatic, internal,
wall-bounded flow. The ARTIST experimental project (Phase I) served as the physical
model replicated for numerical simulation. Realizable k-ε and standard k-ω turbulence
models were selected from the computational fluid dynamics (CFD) code, FLUENT, to
provide the Eulerian description of the gaseous phase.
Flow field simulation results exhibited: a) onset of weak secondary flow
accelerated at bend entrance towards the inner wall; b) flow separation zone
development on the convex wall that persisted from the point of onset; c) centrifugal
force concentrated high velocity flow in the direction of the concave wall; d) formation
of vortices throughout the flow domain resulted from rotational (Dean-type) flow; e)
weakened secondary flow assisted the formation of twin vortices in the outflow cross
section; and f) perturbations induced by the bend influenced flow recovery several pipe diameters upstream of the bend. These observations were consistent with those of
previous investigators.
The Lagrangian discrete random walk model, with and without turbulent
dispersion, simulated the dispersed phase behavior, incorrectly. Accurate deposition
predictions in wall-bounded flow require modification of the Eddy Impaction Model
(EIM). Thus, to circumvent shortcomings of the EIM, the Lagrangian time scale was
changed to a wall function and the root-mean-square (RMS) fluctuating velocities were
modified to account for the strong anisotropic nature of flow in the immediate vicinity of
the wall (boundary layer). Subsequent computed trajectories suggest a precision that
ranges from 0.1% to 0.7%, statistical sampling error. The aerodynamic mass median
diameter (AMMD) at the inlet (5.5 μm) was consistent with the ARTIST experimental
findings. The geometric standard deviation (GSD) varied depending on the scenario
evaluated but ranged from 1.61 to 3.2. At the outlet, the computed AMMD (1.9 μm) had
GSD between 1.12 and 2.76. Decontamination factors (DF), computed based on
deposition from trajectory calculations, were just over 3.5 for the bend and 4.4 at the
outlet. Computed DFs were consistent with expert elicitation cited in NUREG-1150 for
aerosol retention in steam generators.
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Numerical Simulation of Flow Field Inside a Squeeze Film Damper and the Study of the Effect of Cavitation on the Pressure DistributionKhandare, Milind Nandkumar 2010 December 1900 (has links)
Squeeze Film Dampers (SFDs) are employed in high-speed Turbomachinery, particularly aircraft jet engines, to provide external damping. Despite numerous successful applications, it is widely acknowledged that the theoretical models used for SFD design are either overly simplified or incapable of taking into account all the features such as cavitation, air entrainment etc., affecting the performance of a SFD. On the other hand, experimental investigation of flow field and dynamic performance of SFDs can be expensive and time consuming. The current work simulates the flow field inside the dynamically deforming annular gap of a SFD using the commercial computational fluid dynamics (CFD) code Fluent and compares the results to the experimental data of San Andrés and Delgado. The dynamic mesh capability of Fluent and a User Defined Function (UDF) was used to replicate the deforming gap and motion of the rotor respectively.
Two dimensional simulations were first performed with different combinations of rotor whirl speed, operating pressures and with and without incorporating the cavitation model. The fluid used in the simulations was ISO VG 2 Mobil Velocite no. 3. After the successful use of the cavitation model in the 2D case, a 3D model with the same dimensions as the experimental setup was built and meshed. The simulations were run for a whirl speed of 50 Hz and an orbit amplitude of 74 μm with no through flow and an inlet pressure of 31kPa (gauge). The resulting pressures at the mid-span of the SFD land were obtained. They closely agreed with those obtained experimentally by San Andrés and Delgado.
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Mixing Performance Evaluation of a Micromixer Utilizing CFD and micro PIV systemTsai, Ming-Feng 03 September 2005 (has links)
This study proposed a novel design of the passive micromixer which employed several quadrilateral shaped blocks in the micro channel to enhance mixing. Both numerical and experimental investigations have been carry out. Commercial software CFD-ACE was used to simulate the flows. The simulation results showed great agreement with the measured results, implying that Navier¡VStokes¡¦ equations still effectively governs the micro-scope flows in this scale. It is effective to enhance mixing efficiency over wide flow rate ranges. Mixing performance was characterized by Laser-induced-fluorescence system (LIF system) to quantity the concentration distribution in the micro channel .
In addition, Microscopic flow visualization was also setup to visualize the flow field in the micro mixer. Micro-particle image velocimetry (Micro-PIV) was used to measure the flow fields in microchannel filled with deionized water (DI water) . The system utilizes an epifluorescent microscope, 3.3 £gm diameter seed particles, and an high speed CCD camera to record particle-image fields. The vector fields are analyzed using a double-frame cross-correlation algorithm. The stochastic influence of Brownian motion plays a significant role in the accuracy of instantaneous velocity measurements.
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Numerical And Experimental Investigation Of Flow Through A Cavitating VenturiYazici, Bora 01 December 2006 (has links) (PDF)
Cavitating venturies are one of the simplest devices to use on a flow line to control the flow rate without using complex valve and measuring systems. It has no moving parts and complex electronic systems. This simplicity increases the reliability of the venturi and makes it a superior element for the military and critical industrial applications. Although cavitating venturis have many advantages and many areas of use, due to the complexity of the physics behind venturi flows, the characteristics of the venturies are mostly investigated experimentally. In addition, due to their military applications, resources on venturi flows are quite limited in the literature.
In this thesis, venturi flows are investigated numerically and experimentally. Two dimensional, two-dimensional axisymmetric and three dimensional cavitating venturi flows are computed using a commercial flow solver FLUENT. An experimental study is then performed to assess the numerical solutions. The effect of the inlet angle, outlet angle, ratio of throat length to inlet diameter and ratio of throat diameter to inlet diameter on the discharge coefficient, and the oscillation behavior of the cavitating bubble are investigated in details.
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Numerical Investigation On Cooling Of Small Form Factor Computer CasesOrhan, Omer Emre 01 January 2007 (has links) (PDF)
In this study, cooling of small form factor computer is numerically investigated.
The numerical model is analyzed using a commercial computational fluid
dynamics software Icepak&trade / . The effects of grid selection, discretization
schemes and turbulence models are discussed and presented. In addition,
physical phenomena like recirculation and relaminarization are addressed briefly.
For a comparison with the computational fluid dynamics results, an experiment
is conducted and some temperature measurements are obtained from critical
locations inside the chassis.The computational results were found to be in good
agreement with the experimental ones.
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Detailed Design Of Shell-and-tube Heat Exchangers Using CfdOzden, Ender 01 September 2007 (has links) (PDF)
Traditionally Shell-and-tube heat exchangers are designed using correlation based approaches like Kern method and Bell-Delaware method. With the advances in Computational Fluid Dynamics (CFD) software, it is now possible to design small heat exchangers using CFD. In this thesis, shell-and-tube heat exchangers are modeled and numerically analyzed using a commercial finite volume package. The modeled heat exchangers are relatively small, have single shell and tube passes. The leakage effects are not taken into account in the design process. Therefore, there is no leakage from baffle orifices and no gap between baffles and the shell. This study is focused on shell side flow phenomena. First, only shell side is modeled and shell side heat transfer and flow characteristics are analyzed with a series of CFD simulations. Various turbulence models are tried for the first and second order discretization schemes using different mesh densities. CFD predictions of the shell side pressure drop and the heat transfer coefficient are obtained and compared with correlation based method results. After selecting the best modeling approach, the sensitivity of the results to the flow rate, the baffle spacing and baffle cut height are investigated. Then, a simple double pipe heat exchanger is modeled. For the double pipe heat exchanger, both the shell (annulus) side and the tube side are modeled. Last, analyses are performed for a full shell-and-tube heat exchanger model. For that last model, a small laminar educational heat exchanger setup is used. The results are compared with the available experimental results obtained from the setup. Overall, it is observed that the flow and temperature fields obtained from CFD simulations can provide valuable information about the parts of the heat exchanger design that need improvement. The correlation based approaches may indicate the existence of a weakness in design, but CFD simulations can also pin point the source and the location of the weakness.
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Simulation Of Flow Transients In Liquid Pipeline SystemsKoc, Gencer 01 November 2007 (has links) (PDF)
ABSTRACT
SIMULATION OF FLOW TRANSIENTS IN LIQUID PIPELINE SYSTEMS
Koç / , Genç / er
M.S., Department of Mechanical Engineering
Supervisor: Prof. Dr. O. Cahit Eralp
November 2007, 142 pages
In liquid pipeline systems, transient flow is the major cause of pipeline damages.
Transient flow is a situation where the pressure and flow rate in the pipeline rapidly
changes with time. Flow transients are also known as surge and Waterhammer which
originates from the hammering sound of the water in the taps or valves. In liquid
pipelines, preliminary design parameters are chosen for steady state operations, but a
transient check is always necessary. There are various types of transient flow
situations such as valve closures, pump trips and flow oscillations. During a transient
flow, pressure inside the pipe may increase or decrease in an unexpected way that
cannot be foreseen by a steady state analysis. Flow transients should be considered
by a complete procedure that simulates possible transient flow scenarios and by the
obtained results, precautions should be taken.
There are different computational methods that can be used to solve and simulate
flow transients in computer environment. All computational methods utilize basic
v
flow equations which are continuity and momentum equations. These equations are
nonlinear differential equations and some mathematical tools are necessary to make
these equations linear. In this thesis a computer program is coded that utilizes
&ldquo / Method of Characteristics&rdquo / which is a numerical method in solving partial
differential equations. In pipeline hydraulics, two partial differential equations,
continuity and momentum equations are solved together, in order to obtain the
pressure and flow rate values in the pipeline, during transient flow. In this thesis,
MATLAB 7.1 is used as the programming language and obtained code is converted
to a C# language to be able to integrate the core of the program with a user friendly
Graphical User Interface (GUI).
The Computer program is verified for different scenarios with the available real
pipeline data and results of various reputable agencies. The output of the computer
program is the tabulated pressure and flow rate values according to time indexes and
graphical representations of these values. There are also prompts for users warning
about possible dangerous operation modes of the pipeline components.
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