Spelling suggestions: "subject:"calcium."" "subject:"alcium.""
71 |
Cloning and characterization of two novel, low molecular weight CA2+-dependent, mammalian phospholipase A2 genesChen, Ju January 1994 (has links)
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
|
72 |
Calcium diffusion in a mugearite melt.Medford, Gary A., 1947- January 1970 (has links)
No description available.
|
73 |
Investigations of a calcium efficiency trait in cauliflower cultivars /Byrne, Timothy J. 01 January 1993 (has links) (PDF)
No description available.
|
74 |
The Kinetics of Deposition of Calcium Carbonate onto SurfacesKamiti, Mungai January 1994 (has links)
Note:
|
75 |
The effects of diphosphonates and dietary calcium on calcium homeostatic mechanisms of the cow /Yarrington, John Thurman January 1976 (has links)
No description available.
|
76 |
Blebbistatin Protects Rodent Myocytes from Death in Primary Culture via Inhibiting the Sodium/ Calcium Exchanger and the L-type Calcium ChannelGuan, Yinzheng January 2011 (has links)
Introduction: Cardiac disease is a leading cause of mortabity and morbidity in the developed countries. Cultured cardiac myocytes are widely used for exploring the underlying pathophysiology of cardiac disease. Rodents, especially mice with transgenes or gene ablation, have become popular animal models for heart disease research. However, it has been long recognized that rodent myoyctes die during long-term primary culture, which limits the use of genetically altered myocytes for signaling studies. Blebbistatin (BLB), a myosin II ATPase inhibitor, has been used to protect rodent myocytes. The mechanisms underlying the protective effects of this drug are not clear and are the topics of this study. Materials & methods: Adult rat ventricular myocytes (ARVM) were isolated and cultured with or without BLB (10 µM) for 72 hours in comparison with another protective chemical, BDM (10mM). Myocyte death was evaluated by morphology changes and trypan blue staining. The effects of these two drugs on myocyte contraction, intracellular Ca2+ transient ([Ca2+]i, indo-1,410/480), SR Ca2+ content, L-type calcium and Na+ /Ca2+exchanger currents were studied acutely. Neonatal rat ventricular myocytes (NRVM) were isolated from 1-3 days old neonatal rat hearts and cultured. The effect of BDM (10mM BDM) and BLB (10 µM) in the medium on NRVM growth and hypertrophy induced by norepinephrine (NE, 10µM) were determined. Results: 1. Both BDM and BLB promoted myocyte survival in culture at 72 hours but BLB protected more myocytes (Control: 7.0±1.8% vs. BDM: 61.5±6.4% vs. BLB: 74.0±3.2%); 2. ARVM fractional shortening was reduced by BLB to 1.7±0.4% and by BDM to 0.5±0.1% from the baseline of 6.5±0.7%; 3. Acutely, the amplitude of [Ca2+]i (∆ [Ca2+]i) evaluated with indo-1 AM (F410/F480) was depressed by both BDM (0.04±0.01) and BLB (0.07±0.01) compared to control (0.13±0.01). 4. Diastolic Ca2+ was significantly increased by BLB (0.90±0.06) but not by BDM (0.73±0.06) compared to pre-treat values (0.70±0.05); 5. BLB and BDM significantly reduced the SR Ca2+ content, as indicated by the reduced amplitudes of caffeine-induced Ca2+ transients in BLB- and BDM-treated ARVMs (∆[Ca2+]i in BLB vs. BDM vs. baseline: 0.20±0.03, 0.19±0.04, 0.30±0.03). 6. The mechanisms of the protective effects of BDM and BLB were similar but quantitatively different in that BDM reduced more Ca influx through the L-type Ca2+ channel (ICa-L) than BLB (the reduction in BDM-treated cells vs. BLB-treated cells: 70% vs. 40%) while BLB inhibited more Na+/Ca2+exchanger current (75% inhibition) than BDM (40% reduction); 7. Both BDM and BLB inhibited normal NRVM growth and NE-induced hypertrophy and NFAT translocation in NRVMs. Conclusion: These results suggest both BDM and BLB protect rodent myocytes in culture by preventing cytosolic and SR Ca2+ overload by similar mechanisms: inhibiting NCX and reducing the LTCC. The application of BLB to whole-heart studies and myocyte hypertrophy should be extremely cautioned because BLB does alter myocyte Ca2+ handling. / Physiology
|
77 |
Calcium containing crystals in osteoarthritic synovial fluids and joint tissuesSwan, Angela J. January 1995 (has links)
No description available.
|
78 |
Calcium transport by bovine skeletal-muscle mitochondria its relation to calcium control and to postmortem muscle /Mickelson, James Randall. January 1982 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1982. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 194-217).
|
79 |
Le radiocalcium dans l'étude des osPonlot, Robert. January 1959 (has links)
"Dissertation présentée devant la Faculté de médecine, épreuve de l'agrégation de l'enseignement supérieur." / At head of title: Université catholique de Louvain. Chaire de chirurgie orthopédique, Professeur P. Lacroix, et Institut interuniversitaire des sciences nucléaires. Includes bibliographical references.
|
80 |
Le radiocalcium dans l'étude des osPonlot, Robert. January 1959 (has links)
"Dissertation présentée devant la Faculté de médecine, épreuve de l'agrégation de l'enseignement supérieur." / At head of title: Université catholique de Louvain. Chaire de chirurgie orthopédique, Professeur P. Lacroix, et Institut interuniversitaire des sciences nucléaires. Includes bibliographical references.
|
Page generated in 0.0373 seconds