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Investigation of the effect of a novel vitamin E derivative (alpha-TEA) alone and in combination with a known chemotherapuetic agent in human breast cancer using cell culture and animal modelsLawson, Karla Ann 28 August 2008 (has links)
Not available / text
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The mechanism by which retinol decreases β-catenin protein in retinoic acid-resistant colon cancer cellsDillard, Alice Clare 28 August 2008 (has links)
Not available / text
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The mechanism by which retinol decreases β-catenin protein in retinoic acid-resistant colon cancer cellsDillard, Alice Clare 18 August 2011 (has links)
Not available / text
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Functional studies of Epstein-Barr virus latent membrane protein 1 in nasopharyngeal epithelial cellsLi, Hoi-ming, 李海明 January 2004 (has links)
published_or_final_version / abstract / toc / Anatomy / Doctoral / Doctor of Philosophy
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Combating prostate diseases with ethnobotanical drugs: inhibition of prostate cancer cell proliferation by SawPalmetto (Serenoa repens) extractsTam, Chun-wai., 談振偉. January 2003 (has links)
published_or_final_version / abstract / toc / Biochemistry / Master / Master of Philosophy
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FTY720, a novel pharmaceutical therapy for hepatocellular carcinomaLee, Kin-wah, Terence, 李建華 January 2004 (has links)
published_or_final_version / abstract / toc / Molecular Biology / Doctoral / Doctor of Philosophy
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Ultrastructural and stereological investigation of the effects of hexamethylene bisacetamide on human colon carcinoma LoVo cells invitro劉汝這, Lau, Yue-huen, Thomas. January 2000 (has links)
published_or_final_version / abstract / toc / Anatomy / Master / Master of Philosophy
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Investigation of radio- and chemosensitivity mechanisms in Nasopharyngeal Carcinoma cells周淑雅, Chow, S. N. January 2000 (has links)
published_or_final_version / Pathology / Master / Master of Philosophy
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¹H magnetic resonance spectroscopic imaging of tumour extracellular pH : the role of carbonic anhydrase IXLee, Shen-Han January 2013 (has links)
No description available.
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The protective effect of metallothionein against lipid peroxidation caused by retinoic acid in human breast cancer cells /Hurnanen, Darin. January 1996 (has links)
A two by six factorial design was used to investigate the effect of zinc and all-trans retinoic acid (RA) on the growth of two human breast cancer cell lines differing in their expression of metallothionein (MT) and of estrogen receptors; MCF7 cells express estrogen receptors, BT-20 cells do not. Cells were treated with zinc to induce MT then treated with six concentrations of RA. Cell proliferation, lipid peroxidation, MT protein, MT mRNA and glutathione concentrations were measured. / BT-20 cells expressed higher constitutive MT concentrations than MCF7 cells. MT was significantly induced by zinc treatment in BT-20 cells but not in MCF7 cells. Low RA concentrations stimulated growth proliferation but higher concentrations inhibited cell proliferation. High RA concentrations increased lipid peroxidation. There was a significant negative correlation between lipid peroxidation and cell proliferation. Growth inhibition and lipid peroxidation were reduced by zinc in BT-20 cells but not in MCF7 cells. Glutathione did not appear to be a significant factor. / Induction of metallothionein by zinc may modulate the growth inhibitory effects of all-trans retinoic acid in human breast cancer cells. One mechanism of growth inhibition may be through increased lipid peroxidation.
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