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Mechanism of retinoic acid action on the loss of anchorage-independant growth of F9 embryonal carcinoma cellsRodriques, Mabel T. (Mabel Teresa). January 1986 (has links)
No description available.
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Determining the intracellular localization and efficacy of novel anticancer agents in human breast cancer cell lines through the use of fluorescent microscopy /Koegle, Eric Richard. January 2008 (has links)
Thesis (M.S.)--University of Toledo, 2008. / Typescript. "Submitted as partial fulfillments of the requirements for The Master of Science in Pharmaceutical Sciences in Pharmacology and Toxicology." "A thesis entitled"--at head of title. Bibliography: leaves 47-49.
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Roles of PKC isozymes in retinoic acid-induced B16 mouse melanoma cell growth inhibition and differentiationHan, Jianming. January 2004 (has links)
Thesis (Ph. D.)--Marshall University, 2004. / Title from document title page. Document formatted into pages; contains p. xvi, 173 p. Includes abstract. Includes bibliographical references (p. 153-173).
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BIOLOGICAL AND BIOCHEMICAL CHARACTERIZATION OF NORMAL AND TRANSFORMED BALB/C FIBROBLASTSVan Nest, Gary Alan, 1949- January 1977 (has links)
No description available.
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Oncostatic actions of melatonin on tumor cell growth in the LNCaP model of human prostate cancerXi, Sichuan. January 2000 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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In vitro effect of Arsenic trioxide on the common childhood neurogenictumour cell linesRocha, Karen Anne. January 2003 (has links)
published_or_final_version / Paediatrics and Adolescent Medicine / Master / Master of Philosophy
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Evaluation of the efficacy and toxicity of novel fungal extractsMagee, Pamela Jane January 1999 (has links)
No description available.
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Investigations into the roles of female hormones and cytokines on meningioma cell proliferation in vitroBoyle-Walsh, Elizabeth Ann January 1995 (has links)
No description available.
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The biochemical functions of the Retinoblastoma binding protein 6 (RBBP 6) isoforms in metabolic reprogramming occurring during carcinogenesisNsingwane, Zanele January 2018 (has links)
Thesis (M.Sc.)--University of the Witwatersrand, Faculty of Science, School of Molecular and Cell Biology, 2018. / ABSTRACT
The Retinoblastoma binding protein 6 is dysregulated in most cancers, indicating it may play a role in metabolic reprograming- a hallmark of carcinogenesis. Its human isoforms have been shown to play diverse roles in apoptosis. This study aimed to elucidate biochemical roles of RBBP6 isoforms in metabolic reprogramming during carcinogenesis. Drosophila melanogaster wild type and p53 null mutants were treated with drug permutations of irinotecan (DNA damaging agent) and exogenous pyruvate to perturb metabolism. Moreover, using RT-PCR and Western blot expression profiles of SNAMA (Drosophila Orthologue of RBBP6) isoforms were shown followed by survival studies to investigate the effects of these drugs. Furthermore, using bioinformatics the domains of RBBP6 isoforms in various species were shown. Results indicate that RBBP6 isoforms show contrasting expression patterns. Furthermore, exogenous pyruvate protects the wild type flies from irinotecan toxicity while killing p53 null mutants. RBBP6 proves to be a potential druggable target for chemotherapy. / EM2018
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Ginsenosides on the growth and proliferation of glial tumor cellsNg, Wai Yee 01 January 2008 (has links)
No description available.
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