Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-07-20T11:57:50Z No. of bitstreams: 1 thaenycostaamaral.pdf: 3993563 bytes, checksum: 62bc56f6ffb8386752008017f578a088 (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-08-09T12:26:57Z (GMT) No. of bitstreams: 1 thaenycostaamaral.pdf: 3993563 bytes, checksum: 62bc56f6ffb8386752008017f578a088 (MD5) / Made available in DSpace on 2017-08-09T12:26:57Z (GMT). No. of bitstreams: 1 thaenycostaamaral.pdf: 3993563 bytes, checksum: 62bc56f6ffb8386752008017f578a088 (MD5) Previous issue date: 2017-02-23 / No presente trabalho foram descritas as sínteses e as caracterizações do ligante dicloridrato de N,N'-bis(tiofenil-2-metil)etano-1,2-diamina (BNHred.2HCl), dos seus complexos [RuCl2BNHred(PPh3)2], [PtCl2BNHred] e [PdCl2BNHred] e dos sais [BNHred.2H+][PtCl4] e [BNHred.2H+][Au(CN)2]2-. Os compostos foram caracterizados por análise elementar (C, H, N), técnicas espectroscópicas no IV, Raman e RMN (solução e estado sólido), difração de raios X (DRX) por policristais e cálculos de DFT. Para os complexos [PtCl2BNHred] e [PdCl2BNHred] os resultados obtidos pelas técnicas de caracterização corroboram que a coordenação ocorreu pelos átomos de nitrogênio do grupo NH e por dois íons cloretos formando complexos com estrutura quadrática. O complexo [RuCl2BNHred(PPh3)2] teve sua estrutura determinada por DRX por policristais onde foi encontrada a estrutura com geometria octaédrica, tendo o íon Ru(II) coordenado aos grupos NH, de forma quelato, duas PPh3 e dois íons cloreto. Os sais [BNHred.2H+][PtCl4] e [BNHred.2H+][Au(CN)2]2- também tiveram suas estruturas determinadas por DRX (policristais), onde o sal [BNHred.2H+][Au(CN)2]2- se cristaliza em um sistema cristalino ortorrômbico e grupo espacial Pnn2 e o sal [BNHred.2H+][PtCl4] cristaliza-se no sistema triclínico e grupo espacial P-1. Além desses compostos, também foi sintetizado e caracterizado o ligante dinitrato de N,N'-bis(tiofenil-2metil)etano-1,2-diamina (BNHred.2HNO3), no qual teve a estrutura cristalina determinada por DRX (policristais), pertencendo ao sistema cristalino monoclínico e grupo espacial P21/c. Testes biológicos contra Mycobacterium tuberculosis, de todos os compostos obtidos foram realizados, onde o sal [BNHred.2H+][Au(CN)2]2- apresentou o CIM90 de 2,31 mg/L. / The present work, syntheses and characterizations of the ligand N,N’-bis(tiophenyl-2methyl)ethane-1,2-diamino dichlorydrate (BNHred.2HCl), their [RuCl2BNHred(PPh3)2], [PtCl2BNHred] and [PdCl2BNHred] complexes and their [BNHred.2H+][PtCl4] and [BNHred.2H+][Au(CN)2]2- salts were described. The compounds were analyzed by elementare analysis (C, H and N), IR, Raman and NMR (in solution and solid state) spectroscopies as well by powder X ray diffraction and DFT calculations. The [PtCl2BNHred] and [PdCl2BNHred] complexes should be square planar geometry since ligand is coordinated by nitrogen atoms of the NH groups and the coordination sphere is completed by two chlorine ions. The octahedral [RuCl2BNHred(PPh3)2] complex structure was determined/refined by powder X ray diffraction where the Ru(II) ion is coordinated by ligand in chelate mode, also by two PPh3 molecules and by two chloride ions. The [BNHred.2H+][PtCl4] and [BNHred.2H+][Au(CN)2]2- salt structures were also solved by powder X ray diffraction. [BNHred.2H+][Au(CN)2]2- salt crystallizes in orthorhombic system and space group Pnn2, while the [BNHred.2H+][PtCl4] salt belongs to triclinic system and space group P-1. In addition, the ligand N,N’-bis(tiophenyl-2-methyl)ethane-1,2-diamino dinitrate (BNHred.2HNO3) was also synthetized and fully characterized. The BNHred.2HNO3 structure was obtained by powder X ray diffraction and presents a monoclinic crystalline system and space group P21/c. Biological tests against Mycobacterium tuberculosis of all the obtained compounds have been carried out, where the [BNHred.2H+][Au(CN)2]2- salt has been shown MIC90 at 2.31 mg/L.