Made available in DSpace on 2016-04-28T20:17:27Z (GMT). No. of bitstreams: 1 2008 - Ana Claudia da Silva Vila Nova.pdf: 3100692 bytes, checksum: fceb0ab719732f64ea3e29199427d13f (MD5) Previous issue date: 2008-04-16 / Many areas are involved in the search for new substances from plants. The new global trends of a concern for biodiversity and the ideas of sustainable development have brought new air to studies of Brazilian medicinal plants. New lines of research were established in Brazilian universities, some of them seeking solid basis for the validation of the use of medicinal plants, thus justifying this work, using aqueous extracts of plants place of occurrence, such as Cinnamomum spp., Mentha piperita and Passiflora foetida, inhibition of growth of some species of the genus Aspergillus tox?genas, previously studied in the literature and identified as antifungal and encouraging the use of plants to replace chemicals. Using the method of minimum inhibitory concentration in agar, with the technique of dilution plate (Pour-Plate), being held dilutions of different extracts, from a solution of 5% and resulting in the dilution of 2.5% and 1.25%. Batteries tests were incubated at the 36oC. It was held also test for sensitivity to antifungal commercial - Ketoconazole. It was observed that the aqueous extract of Cinnamomum spp. was able to inhibit the mycelial growth of A. flavus and A. carbonarius at concentrations of 2.5% and 5% in readings of 48 hours. The other aqueous extracts, used in this work, showed no inhibitory effect of mycelial growth of fungi tested. / Muitas ?reas est?o envolvidas na pesquisa de novas subst?ncias oriundas de plantas. As novas tend?ncias globais de uma preocupa??o com a biodiversidade e as id?ias de desenvolvimento sustent?vel trouxeram novos ares aos estudos das plantas medicinais brasileiras. Novas linhas de pesquisa foram estabelecidas em universidades brasileiras, algumas delas buscando bases s?lidas para a valida??o do uso de plantas medicinais, justificando, assim, a realiza??o deste trabalho, utilizando extratos aquosos de plantas de ocorr?ncia local, como a Cinnamomum spp., Mentha piperita e Passiflora foetida, na inibi??o do crescimento de algumas esp?cies tox?genas do g?nero Aspergillus, previamente pesquisadas na literatura e apontadas como antif?ngicas e favorecendo a utiliza??o de plantas em substitui??o de produtos qu?micos. Utilizando o m?todo da concentra??o m?nima inibit?ria em agar, com a t?cnica de dilui??o em placa (Pour-Plate), sendo realizadas dilui??es dos diferentes extratos, partindo de uma solu??o de 5% e obtendo-se as dilui??es de 2,5% e 1,25%. As baterias testes foram incubadas a 36o C. Foi realizado, tamb?m, teste de sensibilidade ao antif?ngico comercial Cetoconazol. Observou-se que o extrato aquoso de Cinnamomum spp. mostrou-se capaz de inibir o crescimento micelial de A. flavus e A. carbonarius nas concentra??es de 2,5% e 5%, nas leituras de 48 horas. Os demais extratos aquosos, utilizados neste trabalho, n?o apresentaram efeito inibit?rio do crescimento micelial dos fungos testados.