Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-09-05T19:56:02Z No. of bitstreams: 1 SamilaNeresDeOliveira_DISSERT.pdf: 989578 bytes, checksum: 0d9d4bbfe814cd988071e39d3062f876 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-09-15T23:53:31Z (GMT) No. of bitstreams: 1 SamilaNeresDeOliveira_DISSERT.pdf: 989578 bytes, checksum: 0d9d4bbfe814cd988071e39d3062f876 (MD5) / Made available in DSpace on 2017-09-15T23:53:31Z (GMT). No. of bitstreams: 1 SamilaNeresDeOliveira_DISSERT.pdf: 989578 bytes, checksum: 0d9d4bbfe814cd988071e39d3062f876 (MD5) Previous issue date: 2017-07-10 / A sensibilidade ? o principal efeito adverso causado pelo clareamento dent?rio. O presente estudo tem como objetivo comparar a efic?cia dos f?rmacos ibuprofeno e a associa??o de code?na + paracetamol, no controle da sensibilidade imediata gerada pelo clareamento dent?rio de consult?rio com per?xido de hidrog?nio a 35%. M?todos: Foram selecionados aleatoriamente 60 volunt?rios e os mesmos foram divididos em 3 grupos: Placebo (PL) 400 mg (n= 20), Ibuprofeno (IB) 400 mg (n= 20) e associa??o de Code?na 30 mg + Paracetamol 500 mg (CP) (n= 20). Os volunt?rios foram submetidos a 2 sess?es de clareamento com per?xido de hidrog?nio 35% em 2 aplica??es de 20 min cada. As medica??es foram tomadas 1 hora antes do procedimento clareador em ambas as sess?es. Os valores de sensibilidade foram coletados utilizando uma escala visual anal?gica de dor. A an?lise estat?stica foi feita atrav?s do teste de ANOVA 1 Fator e p?s teste de tukey, utilizando o software Assistat?. Resultados: Houve diferen?a estatisticamente significativa entre os tratamentos (p<0,01) (m?dias: PL: 4,7; IB: 4,8 e CP: 1,0). Conclus?o: O tratamento da associa??o de code?na + paracetamol foi mais eficaz em eliminar a sensibilidade imediata gerada pelo clareamento dent?rio com per?xido de hidrog?nio 35%, com valores bem pr?ximos de zero, em compara??o as medica??es ibuprofeno e placebo. / Sensitivity is the main adverse effect caused by tooth whitening. The aim of the present study was to compare the efficacy of ibuprofen and the combination of codeine + paracetamol in the control of the immediate sensitivity generated by dental office whitening with 35% hydrogen peroxide. Methods: Sixty volunteers were randomly selected and divided into three groups: Placebo (PL) 400 mg (n = 20), Ibuprofen (IB) 400 mg (n = 20) and Codeine 30 mg + Paracetamol 500 mg (N = 20). The volunteers were submitted to 2 bleaching sessions with 35% hydrogen peroxide in 2 applications of 20 min each. Medications were taken 1 hour before the bleaching procedure in both sessions. Sensitivity values were collected using a visual analog pain scale. Statistical analysis was done using ANOVA 1 Factor and post test of tukey, using Assistat? software. Results: There was a statistically significant difference between the treatments (p <0.01) (averages: PL: 4.7, IB: 4.8 and CP: 1.0). Conclusion: The treatment of codeine + paracetamol was more effective in eliminating the immediate sensitivity generated by tooth whitening with 35% hydrogen peroxide, with values close to zero, compared to ibuprofen and placebo.