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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
61

Viabilidade técnica e econômica do condicionamento geotérmico de edificações no Rio Grande do Sul / Technical and economic feasibility of geothermal conditioning of buildings in Rio Grande do Sul

Barcelos, Roberto Hubner January 2018 (has links)
O elevado consumo energético de edificações para o seu condicionamento térmico já é um dos maiores impactos ambientais da construção civil nos países desenvolvidos e, progressivamente, vem se tornando uma preocupação também nos países em desenvolvimento. Uma alternativa renovável relativamente recente, tanto para aquecimento como para resfriamento, são as bombas de calor geotérmicas (ground source heat pumps, GSHPs), que se valem da inércia térmica do solo para reduzir significativamente a demanda energética em relação ao ar. Apesar do seu grande potencial em reduzir o consumo de energia e as emissões de carbono, esta tecnologia ainda é quase inexistente na América Latina, não somente devido à falta de conhecimento ao seu respeito, mas também pela incerteza quanto à sua viabilidade frente a um custo inicial mais elevado. Embora existam muitas pesquisas sobre o funcionamento de GSHPs, grande parte do conhecimento prático quanto ao projeto, desempenho e viabilidade é baseada na experiência dos primeiros países onde a tecnologia começou a se tornar popular, e não pode ser assumida automaticamente como válida em outras situações sem uma avaliação prévia Estudos anteriores apontaram que o retorno econômico de GSHPs tende a ser maior em climas mais frios, enquanto a eficiência tende a ser maior em climas mais amenos, mas com sazonalidade. Por apresentar um bom balanço destas características, o Estado do Rio Grande do Sul apresenta potencial para um desempenho elevado de GSHPs. O objetivo deste trabalho é estimar os níveis de eficiência que esta tecnologia pode atingir em uma cidade de referência no Estado, assim como seu retorno econômico frente a ASHPs (air source heat pumps, ou seja, aparelhos de ar condicionado, ou A/C), seus limitantes e as dificuldades de projeto. Uma edificação unifamiliar residencial em Porto Alegre, projetada especialmente para estudos de sustentabilidade, foi utilizada como caso de estudo para o projeto conceitual completo de um GSHP vertical, um GSHP horizontal e um ASHP. Foram estimadas a demanda de energia e os custos de operação e de implantação para determinadas condições, que foram comparadas em um estudo de viabilidade econômica. Após, os resultados foram extrapolados por uma análise de sensitividade para condições mais genéricas de consumo. Através dos cálculos, observou-se que a tecnologia de GSHPs atingiu o dobro da eficiência dos A/C mais eficientes disponíveis para o caso de estudo. Economicamente, a tecnologia também se mostrou viável, e foram estimados limitantes econômicos a esta viabilidade. Por fim, o processo de projeto desenvolvido pode servir de auxílio a novos projetistas na área. / The high energy consumption in buildings for their thermal conditioning is already one of the greatest environmental impacts of civil construction in developed countries and, progressively, is also becoming a concern in the developing countries. A relatively recent renewable alternative, as much for heating as for cooling, are the ground source heat pumps, GSHPs, which take advantage of the thermal inertia of the ground to significantly decrease the energy demand comparing to air as a source. In spite of their huge potential for decreasing energy comsumption and carbon emissions, this technology is still almost inexistent in Latin America, due not only to lack of awareness, but mainly to uncertainties about their feasibility because of their higher investment cost. Although there are many researches about the characteristics and operation of GSHPs, great part of the practical knowledge as to the design, performance and feasibility is based in the experience from the first countries where the technology spreaded, and cannot be automatically assumed as valid without a previous evaluation. Former studies indicated that the economic profit of GSHPs tends to be higher in colder climates, while the efficiency tends to be higher in milder, but still seasonal climates. For presenting a good balance among these factors, the Rio Grande do Sul State shows potential for a high performance of GSHPs The objective of this work is to estimate the efficiency levels that can be reached by this technology in a reference city in the State, as its financial feedback compared to ASHPs (air source heat pumps, the traditional air conditioners, or A/C), its limitations and the design difficulties. A residential single-family building in Porto Alegre, specifically designed for sustainability studies, was used as case study for the complete conceptual design of a vertical GSHP, a horizontal GSHP and an ASHP. The energy demand and operation and installation costs for specific conditions were estimated and compared in a economic feasibility study. After, the results were extrapolated through a sensitivity analysis for more generic situations of consumption. Through the calculations, it was observed that the technology achieved twice the efficiency of the most efficient A/C available for the case study. Economically, the technology showed itself viable, and economic limitations were also estimated. At last, the developed design process can also serve as aid to new designers in the field.
62

Three-dimensional computational investigations of flow mechanisms in compound meandering channels

Shukla, Deepak R. January 2006 (has links)
Flow mechanisms of compound meandering channels are recognised to be far more complicated than compound straight channels. The compound meandering channels are mainly characterised by the continuous variation of mean and turbulent flow parameters along a meander wavelength; the existence of horizontal shear layer at the bankfull level and the presence of strong helical secondary flow circulations in the streamwise direction. The secondary flow circulations are very important as they govern the advection of flow momentum, distort isovels, and influence bed shear stress, thus producing a complicated and fully three-dimensional turbulent flow structures. A great deal of experiments has been conducted in the past, which explains flow mechanisms, mixing patterns and the behaviour of secondary flow circulations. However, a complete understanding of secondary flow structures still remains far from conclusive mainly because the secondary flow structures are influenced by the host of geometrical and flow parameters, which are yet to be investigated in detail. The three-dimensional Reynolds-averaged Navier-Stokes and continuity equations were solved using a standard Computational Fluid Dynamics solver to predict mean velocity, secondary flow and turbulent kinetic energy. Five different flow cases of various model scales and relative depths were considered. Detailed analyses of the measured and predicted flow variables were carried out to understand mean flow mechanisms and turbulent secondary flow structures in compound meandering channels. The streamwise vorticity equation was used to quantify the complex and three-dimensional behaviour of secondary flow circulations in terms of their generation, development and decay along the half-meander wavelength. The turbulent kinetic energy equation was used to understand energy expense mechanisms of secondary flow circulations. The strengths of secondary flow circulations were calculated and compared for different flow cases considered. The main findings from this research are as follows. The shearing of the main channel flow as the floodplain flow plunges into and over the main channel influences the mean and turbulent flow structures particularly in the crossover region. The horizontal shear layer at the inner bankfull level generates secondary flow circulations. As the depth of flow increases, the point of generation of secondary flow circulations moves downstream. The secondary shear stress significantly contributes towards the generation of streamwise vorticity and the production of turbulent kinetic energy. The rate of turbulence kinetic energy production was found to be higher than the rate of its dissipation in the crossover region, which demonstrates that the turbulence extracts more energy from the mean flu\\' than what is actually dissipated. This also implies that, in the crossover region, the turbulence is always advected downstream by the mean and secondary flows, The strength of geometry induced secondary flow circulation increases with the increase in the relative depth.
63

Viabilidade técnica e econômica do condicionamento geotérmico de edificações no Rio Grande do Sul / Technical and economic feasibility of geothermal conditioning of buildings in Rio Grande do Sul

Barcelos, Roberto Hubner January 2018 (has links)
O elevado consumo energético de edificações para o seu condicionamento térmico já é um dos maiores impactos ambientais da construção civil nos países desenvolvidos e, progressivamente, vem se tornando uma preocupação também nos países em desenvolvimento. Uma alternativa renovável relativamente recente, tanto para aquecimento como para resfriamento, são as bombas de calor geotérmicas (ground source heat pumps, GSHPs), que se valem da inércia térmica do solo para reduzir significativamente a demanda energética em relação ao ar. Apesar do seu grande potencial em reduzir o consumo de energia e as emissões de carbono, esta tecnologia ainda é quase inexistente na América Latina, não somente devido à falta de conhecimento ao seu respeito, mas também pela incerteza quanto à sua viabilidade frente a um custo inicial mais elevado. Embora existam muitas pesquisas sobre o funcionamento de GSHPs, grande parte do conhecimento prático quanto ao projeto, desempenho e viabilidade é baseada na experiência dos primeiros países onde a tecnologia começou a se tornar popular, e não pode ser assumida automaticamente como válida em outras situações sem uma avaliação prévia Estudos anteriores apontaram que o retorno econômico de GSHPs tende a ser maior em climas mais frios, enquanto a eficiência tende a ser maior em climas mais amenos, mas com sazonalidade. Por apresentar um bom balanço destas características, o Estado do Rio Grande do Sul apresenta potencial para um desempenho elevado de GSHPs. O objetivo deste trabalho é estimar os níveis de eficiência que esta tecnologia pode atingir em uma cidade de referência no Estado, assim como seu retorno econômico frente a ASHPs (air source heat pumps, ou seja, aparelhos de ar condicionado, ou A/C), seus limitantes e as dificuldades de projeto. Uma edificação unifamiliar residencial em Porto Alegre, projetada especialmente para estudos de sustentabilidade, foi utilizada como caso de estudo para o projeto conceitual completo de um GSHP vertical, um GSHP horizontal e um ASHP. Foram estimadas a demanda de energia e os custos de operação e de implantação para determinadas condições, que foram comparadas em um estudo de viabilidade econômica. Após, os resultados foram extrapolados por uma análise de sensitividade para condições mais genéricas de consumo. Através dos cálculos, observou-se que a tecnologia de GSHPs atingiu o dobro da eficiência dos A/C mais eficientes disponíveis para o caso de estudo. Economicamente, a tecnologia também se mostrou viável, e foram estimados limitantes econômicos a esta viabilidade. Por fim, o processo de projeto desenvolvido pode servir de auxílio a novos projetistas na área. / The high energy consumption in buildings for their thermal conditioning is already one of the greatest environmental impacts of civil construction in developed countries and, progressively, is also becoming a concern in the developing countries. A relatively recent renewable alternative, as much for heating as for cooling, are the ground source heat pumps, GSHPs, which take advantage of the thermal inertia of the ground to significantly decrease the energy demand comparing to air as a source. In spite of their huge potential for decreasing energy comsumption and carbon emissions, this technology is still almost inexistent in Latin America, due not only to lack of awareness, but mainly to uncertainties about their feasibility because of their higher investment cost. Although there are many researches about the characteristics and operation of GSHPs, great part of the practical knowledge as to the design, performance and feasibility is based in the experience from the first countries where the technology spreaded, and cannot be automatically assumed as valid without a previous evaluation. Former studies indicated that the economic profit of GSHPs tends to be higher in colder climates, while the efficiency tends to be higher in milder, but still seasonal climates. For presenting a good balance among these factors, the Rio Grande do Sul State shows potential for a high performance of GSHPs The objective of this work is to estimate the efficiency levels that can be reached by this technology in a reference city in the State, as its financial feedback compared to ASHPs (air source heat pumps, the traditional air conditioners, or A/C), its limitations and the design difficulties. A residential single-family building in Porto Alegre, specifically designed for sustainability studies, was used as case study for the complete conceptual design of a vertical GSHP, a horizontal GSHP and an ASHP. The energy demand and operation and installation costs for specific conditions were estimated and compared in a economic feasibility study. After, the results were extrapolated through a sensitivity analysis for more generic situations of consumption. Through the calculations, it was observed that the technology achieved twice the efficiency of the most efficient A/C available for the case study. Economically, the technology showed itself viable, and economic limitations were also estimated. At last, the developed design process can also serve as aid to new designers in the field.
64

Computational modelling of the human heart and multiscale simulation of its electrophysiological activity aimed at the treatment of cardiac arrhythmias related to ischaemia and Infarction

López Pérez, Alejandro Daniel 02 September 2019 (has links)
[ES] Las enfermedades cardiovasculares constituyen la principal causa de morbilidad y mortalidad a nivel mundial, causando en torno a 18 millones de muertes cada año. De entre ellas, la más común es la enfermedad isquémica cardíaca, habitualmente denominada como infarto de miocardio (IM). Tras superar un IM, un considerable número de pacientes desarrollan taquicardias ventriculares (TV) potencialmente mortales durante la fase crónica del IM, es decir, semanas, meses o incluso años después la fase aguda inicial. Este tipo concreto de TV normalmente se origina por una reentrada a través de canales de conducción (CC), filamentos de miocardio superviviente que atraviesan la cicatriz del infarto fibrosa y no conductora. Cuando los fármacos anti-arrítmicos resultan incapaces de evitar episodios recurrentes de TV, la ablación por radiofrecuencia (ARF), un procedimiento mínimamente invasivo realizado mediante cateterismo en el laboratorio de electrofisiología (EF), se usa habitualmente para interrumpir de manera permanente la propagación eléctrica a través de los CCs responsables de la TV. Sin embargo, además de ser invasivo, arriesgado y requerir mucho tiempo, en casos de TVs relacionadas con IM crónico, hasta un 50% de los pacientes continúa padeciendo episodios recurrentes de TV tras el procedimiento de ARF. Por tanto, existe la necesidad de desarrollar nuevas estrategias pre-procedimiento para mejorar la planificación de la ARF y, de ese modo, aumentar esta tasa de éxito relativamente baja. En primer lugar, realizamos una revisión exhaustiva de la literatura referente a los modelos cardiacos 3D existentes, con el fin de obtener un profundo conocimiento de sus principales características y los métodos usados en su construcción, con especial atención sobre los modelos orientados a simulación de EF cardíaca. Luego, usando datos clínicos de un paciente con historial de TV relacionada con infarto, diseñamos e implementamos una serie de estrategias y metodologías para (1) generar modelos computacionales 3D específicos de paciente de ventrículos infartados que puedan usarse para realizar simulaciones de EF cardíaca a nivel de órgano, incluyendo la cicatriz del infarto y la región circundante conocida como zona de borde (ZB); (2) construir modelos 3D de torso que permitan la obtención del ECG simulado; y (3) llevar a cabo estudios in-silico de EF personalizados y pre-procedimiento, tratando de replicar los verdaderos estudios de EF realizados en el laboratorio de EF antes de la ablación. La finalidad de estas metodologías es la de localizar los CCs en el modelo ventricular 3D para ayudar a definir los objetivos de ablación óptimos para el procedimiento de ARF. Por último, realizamos el estudio retrospectivo por simulación de un caso, en el que logramos inducir la TV reentrante relacionada con el infarto usando diferentes configuraciones de modelado para la ZB. Validamos nuestros resultados mediante la reproducción, con una precisión razonable, del ECG del paciente en TV, así como en ritmo sinusal a partir de los mapas de activación endocárdica obtenidos invasivamente mediante sistemas de mapeado electroanatómico en este último caso. Esto permitió encontrar la ubicación y analizar las características del CC responsable de la TV clínica. Cabe destacar que dicho estudio in-silico de EF podría haberse efectuado antes del procedimiento de ARF, puesto que nuestro planteamiento está completamente basado en datos clínicos no invasivos adquiridos antes de la intervención real. Estos resultados confirman la viabilidad de la realización de estudios in-silico de EF personalizados y pre-procedimiento de utilidad, así como el potencial del abordaje propuesto para llegar a ser en un futuro una herramienta de apoyo para la planificación de la ARF en casos de TVs reentrantes relacionadas con infarto. No obstante, la metodología propuesta requiere de notables mejoras y validación por medio de es / [CA] Les malalties cardiovasculars constitueixen la principal causa de morbiditat i mortalitat a nivell mundial, causant entorn a 18 milions de morts cada any. De elles, la més comuna és la malaltia isquèmica cardíaca, habitualment denominada infart de miocardi (IM). Després de superar un IM, un considerable nombre de pacients desenvolupen taquicàrdies ventriculars (TV) potencialment mortals durant la fase crònica de l'IM, és a dir, setmanes, mesos i fins i tot anys després de la fase aguda inicial. Aquest tipus concret de TV normalment s'origina per una reentrada a través dels canals de conducció (CC), filaments de miocardi supervivent que travessen la cicatriu de l'infart fibrosa i no conductora. Quan els fàrmacs anti-arítmics resulten incapaços d'evitar episodis recurrents de TV, l'ablació per radiofreqüència (ARF), un procediment mínimament invasiu realitzat mitjançant cateterisme en el laboratori de electrofisiologia (EF), s'usa habitualment per a interrompre de manera permanent la propagació elèctrica a través dels CCs responsables de la TV. No obstant això, a més de ser invasiu, arriscat i requerir molt de temps, en casos de TVs relacionades amb IM crònic fins a un 50% dels pacients continua patint episodis recurrents de TV després del procediment d'ARF. Per tant, existeix la necessitat de desenvolupar noves estratègies pre-procediment per a millorar la planificació de l'ARF i, d'aquesta manera, augmentar la taxa d'èxit, que es relativament baixa. En primer lloc, realitzem una revisió exhaustiva de la literatura referent als models cardíacs 3D existents, amb la finalitat d'obtindre un profund coneixement de les seues principals característiques i els mètodes usats en la seua construcció, amb especial atenció sobre els models orientats a simulació de EF cardíaca. Posteriorment, usant dades clíniques d'un pacient amb historial de TV relacionada amb infart, dissenyem i implementem una sèrie d'estratègies i metodologies per a (1) generar models computacionals 3D específics de pacient de ventricles infartats capaços de realitzar simulacions de EF cardíaca a nivell d'òrgan, incloent la cicatriu de l'infart i la regió circumdant coneguda com a zona de vora (ZV); (2) construir models 3D de tors que permeten l'obtenció del ECG simulat; i (3) dur a terme estudis in-silico de EF personalitzats i pre-procediment, tractant de replicar els vertaders estudis de EF realitzats en el laboratori de EF abans de l'ablació. La finalitat d'aquestes metodologies és la de localitzar els CCs en el model ventricular 3D per a ajudar a definir els objectius d'ablació òptims per al procediment d'ARF. Finalment, a manera de prova de concepte, realitzem l'estudi retrospectiu per simulació d'un cas, en el qual aconseguim induir la TV reentrant relacionada amb l'infart usant diferents configuracions de modelatge per a la ZV. Validem els nostres resultats mitjançant la reproducció, amb una precisió raonable, del ECG del pacient en TV, així com en ritme sinusal a partir dels mapes d'activació endocardíac obtinguts invasivament mitjançant sistemes de mapatge electro-anatòmic en aquest últim cas. Això va permetre trobar la ubicació i analitzar les característiques del CC responsable de la TV clínica. Cal destacar que aquest estudi in-silico de EF podria haver-se efectuat abans del procediment d'ARF, ja que el nostre plantejament està completament basat en dades clíniques no invasius adquirits abans de la intervenció real. Aquests resultats confirmen la viabilitat de la realització d'estudis in-silico de EF personalitzats i pre-procediment d'utilitat, així com el potencial de l'abordatge proposat per a arribar a ser en un futur una eina de suport per a la planificació de l'ARF en casos de TVs reentrants relacionades amb infart. No obstant això, la metodologia proposada requereix de notables millores i validació per mitjà d'estudis de simulació amb grans cohorts de pacients. / [EN] Cardiovascular diseases represent the main cause of morbidity and mortality worldwide, causing around 18 million deaths every year. Among these diseases, the most common one is the ischaemic heart disease, usually referred to as myocardial infarction (MI). After surviving to a MI, a considerable number of patients develop life-threatening ventricular tachycardias (VT) during the chronic stage of the MI, that is, weeks, months or even years after the initial acute phase. This particular type of VT is typically sustained by reentry through slow conducting channels (CC), which are filaments of surviving myocardium that cross the non-conducting fibrotic infarct scar. When anti-arrhythmic drugs are unable to prevent recurrent VT episodes, radiofrequency ablation (RFA), a minimally invasive procedure performed by catheterization in the electrophysiology (EP) laboratory, is commonly used to interrupt the electrical conduction through the CCs responsible for the VT permanently. However, besides being invasive, risky and time-consuming, in the cases of VTs related to chronic MI, up to 50% of patients continue suffering from recurrent VT episodes after the RFA procedure. Therefore, there exists a need to develop novel pre-procedural strategies to improve RFA planning and, thereby, increase this relatively low success rate. First, we conducted an exhaustive review of the literature associated with the existing 3D cardiac models in order to gain a deep knowledge about their main features and the methods used for their construction, with special focus on those models oriented to simulation of cardiac EP. Later, using a clinical dataset of a chronically infarcted patient with a history of infarct-related VT, we designed and implemented a number of strategies and methodologies to (1) build patient-specific 3D computational models of infarcted ventricles that can be used to perform simulations of cardiac EP at the organ level, including the infarct scar and the surrounding region known as border zone (BZ); (2) construct 3D torso models that enable to compute the simulated ECG; and (3) carry out pre-procedural personalized in-silico EP studies, trying to replicate the actual EP studies conducted in the EP laboratory prior to the ablation. The goal of these methodologies is to allow locating the CCs into the 3D ventricular model in order to help in defining the optimal ablation targets for the RFA procedure. Lastly, as a proof-of-concept, we performed a retrospective simulation case study, in which we were able to induce an infarct-related reentrant VT using different modelling configurations for the BZ. We validated our results by reproducing with a reasonable accuracy the patient's ECG during VT, as well as in sinus rhythm from the endocardial activation maps invasively recorded via electroanatomical mapping systems in this latter case. This allowed us to find the location and analyse the features of the CC responsible for the clinical VT. Importantly, such in-silico EP study might have been conducted prior to the RFA procedure, since our approach is completely based on non-invasive clinical data acquired before the real intervention. These results confirm the feasibility of performing useful pre-procedural personalized in-silico EP studies, as well as the potential of the proposed approach to become a helpful tool for RFA planning in cases of infarct-related reentrant VTs in the future. Nevertheless, the developed methodology requires further improvements and validation by means of simulation studies including large cohorts of patients. / During the carrying out of this doctoral thesis, the author Alejandro Daniel López Pérez was financially supported by the Ministerio de Economía, Industria y Competitividad of Spain through the program Ayudas para contratos predoctorales para la formación de doctores, with the grant number BES-2013-064089. / López Pérez, AD. (2019). Computational modelling of the human heart and multiscale simulation of its electrophysiological activity aimed at the treatment of cardiac arrhythmias related to ischaemia and Infarction [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/124973 / TESIS
65

Výpočtové modelování mechanických zkoušek izolovaných buněk / Computational modelling of mechanical tests of isolated cells

Sůkal, Petr January 2009 (has links)
The master’s thesis deals with computational modelling of mechanical testing of isolated cells, particularly of single-axle tensile test. The aim is to imitate the real deformed shape known from experiments. At first, the structure of each cell component is described and analyzed according to their significance for mechanical behavior. The outline of basic mechanical tests used for cell testing is discussed next. A structural computational model comprising all components significant for mechanical purposes is created for the modelling. Those components are nucleus, cytoplasm, cell membrane and cytoskeleton. Due to the problems with convergence the model was divided into two parts. The first one treats separately the shape of cytoskeleton and the second one treats the shape of communicating components (nucleus, cytoplasm and cell membrane). Both of those partial models succeed in reaching the deformations according to the experiments.
66

A Computational Model for Fracture Healing Integrated with Mechanical Stimulation and Growth Factors

Jernberg, Cassandra January 2014 (has links)
Non-union bone fractures are a standing problem for clinical treatments. It has been found that the exogenous growth factor recombinant human bone morphogenetic protein-2 (rhBMP-2) induces bone healing in potential non-union fractures. However, the currently used clinical dose of rhBMP-2 is high and causes side-effects. Mechanical loading is known to enhance the induced effects of rhBMP-2 in bone healing, which may lead to a reduced required dose. Yet, the exact underlying mechanism is unknown. To further investigate the combined role of mechanical loading and rhBMP-2 in the early phase of fracture healing a 2D computational model was developed. The model uses a lattice-based approach where biological rule-based events are combined with finite element analysis to simulate both untreated bone healing progression and when subjected to mechanical loading and rhBMP-2. Two healing cases were investigated:  normal fracture healing in a small bone defect (1 mm gap) and non-union fracture healing in a large bone defect (5 mm gap). By varying the magnitude and timing of applied load as well as the rhBMP-2 dose, a combination that would reduce the currently used rhBMP-2 dose and still enable healing in a large bone defect was searched. The model could simulate fracture healing in a large bone defect when subjected to rhBMP-2, independently of the applied load. Also the expected non-union result in a large bone defect without applied rhBMP-2 was obtained. The model could not capture normal fracture healing in a small bone defect as well as bone remodelling. It was found that a 50 % reduced rhBMP-2 dose could not induce healing in a large bone defect when applied separately but when applied together with load. Additionally, this combination of stimulation gave similar results compared to other combinations using higher rhBMP-2 doses. To conclude, even though the model was able to replicate some of the healing events seen experimentally, it is in need of modifications to correct current deficiencies. Still, after some further development and validation, the model has the potential to be used in future studies of fracture healing when influenced by mechanical loading and rhBMP-2. The found possibility for a reduced dosage of rhBMP-2 when applied together with load has to be further investigated before any conclusions can be drawn.
67

Spinodal-assisted Phase Transformation Pathways in Multi-Principal Element Alloys

Kadirvel, Kamalnath 28 September 2022 (has links)
No description available.
68

Friendship based trust model to secure routing protocols in mobile Ad Hoc networks

Shabut, Antesar R.M., Dahal, Keshav P., Awan, Irfan U. January 2014 (has links)
No / Trust management in mobile ad hoc networks (MANETs) has become a significant issue in securing routing protocols to choose reliable and trusted paths. Trust is used to cope with defection problems of nodes and stimulate them to cooperate. However, trust is a highly complex concept because of the subjective nature of trustworthiness, and has several social properties, due to its social origins. In this paper, a friendship-based trust model is proposed for MANETs to secure routing protocol from source to destination, in which multiple social degrees of friendships are introduced to represent the degree of nodes' trustworthiness. The model considers the behaviour of nodes as a human pattern to reflect the complexity of trust subjectivity and different views. More importantly, the model considers the dynamic differentiation of friendship degree over time, and utilises both direct and indirect friendship-based trust information. The model overcomes the limitation of neglecting the social behaviours of nodes when evaluating trustworthiness. The empirical analysis shows the greater robustness and accuracy of the trust model in a dynamic MANET environment.
69

Analysis of cloud testbeds using opensource solutions

Mohammed, Bashir, Kiran, Mariam January 2015 (has links)
Cloud computing is increasingly attracting large attention both in academic research and in industrial initiatives. However, despite the popularity, there is a lack of research on the suitability of software tools and parameters for creating and deploying Cloud test beds. Virtualization and how to set up virtual environments can be done through software tools, which are available as open source, but there still needs to be work in terms of which tools to use and how to monitor parameters with the suitability of hardware resources available. This paper discusses the concepts of virtualization, as a practical view point, presenting an in-depth critical analysis of open source cloud implementation tools such as CloudStack, Eucalyptus, Nimbus, OpenStack, OpenNebula, OpenIoT, to name a few. This paper analyzes the various toolkits, parameters of these tools, and their usability for researchers looking to deploy their own Cloud test beds. The paper also extends further in developing an experimental case study of using OpenStack to construct and deploy a test bed using current resources available in the labs at the University of Bradford. This paper contributes to the theme of software setups and open source issues for developing Cloud test bed for deploying and constructing private Cloud test bed.
70

Neural network modelling for shear strength of concrete members reinforced with FRP bars

Bashir, Rizwan, Ashour, Ashraf 10 April 2012 (has links)
yes / This paper investigates the feasibility of using artificial neural networks (NNs) to predict the shear capacity of concrete members reinforced longitudinally with fibre reinforced polymer (FRP) bars, and without any shear reinforcement. An experimental database of 138 test specimens failed in shear is created and used to train and test NNs as well as to assess the accuracy of three existing shear design methods. The created NN predicted to a high level of accuracy the shear capacity of FRP reinforced concrete members. Garson index was employed to identify the relative importance of the influencing parameters on the shear capacity based on the trained NNs weightings. A parametric analysis was also conducted using the trained NN to establish the trend of the main influencing variables on the shear capacity. Many of the assumptions made by the shear design methods are predicted by the NN developed; however, few are inconsistent with the NN predictions.

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