O elevado consumo energético de edificações para o seu condicionamento térmico já é um dos maiores impactos ambientais da construção civil nos países desenvolvidos e, progressivamente, vem se tornando uma preocupação também nos países em desenvolvimento. Uma alternativa renovável relativamente recente, tanto para aquecimento como para resfriamento, são as bombas de calor geotérmicas (ground source heat pumps, GSHPs), que se valem da inércia térmica do solo para reduzir significativamente a demanda energética em relação ao ar. Apesar do seu grande potencial em reduzir o consumo de energia e as emissões de carbono, esta tecnologia ainda é quase inexistente na América Latina, não somente devido à falta de conhecimento ao seu respeito, mas também pela incerteza quanto à sua viabilidade frente a um custo inicial mais elevado. Embora existam muitas pesquisas sobre o funcionamento de GSHPs, grande parte do conhecimento prático quanto ao projeto, desempenho e viabilidade é baseada na experiência dos primeiros países onde a tecnologia começou a se tornar popular, e não pode ser assumida automaticamente como válida em outras situações sem uma avaliação prévia Estudos anteriores apontaram que o retorno econômico de GSHPs tende a ser maior em climas mais frios, enquanto a eficiência tende a ser maior em climas mais amenos, mas com sazonalidade. Por apresentar um bom balanço destas características, o Estado do Rio Grande do Sul apresenta potencial para um desempenho elevado de GSHPs. O objetivo deste trabalho é estimar os níveis de eficiência que esta tecnologia pode atingir em uma cidade de referência no Estado, assim como seu retorno econômico frente a ASHPs (air source heat pumps, ou seja, aparelhos de ar condicionado, ou A/C), seus limitantes e as dificuldades de projeto. Uma edificação unifamiliar residencial em Porto Alegre, projetada especialmente para estudos de sustentabilidade, foi utilizada como caso de estudo para o projeto conceitual completo de um GSHP vertical, um GSHP horizontal e um ASHP. Foram estimadas a demanda de energia e os custos de operação e de implantação para determinadas condições, que foram comparadas em um estudo de viabilidade econômica. Após, os resultados foram extrapolados por uma análise de sensitividade para condições mais genéricas de consumo. Através dos cálculos, observou-se que a tecnologia de GSHPs atingiu o dobro da eficiência dos A/C mais eficientes disponíveis para o caso de estudo. Economicamente, a tecnologia também se mostrou viável, e foram estimados limitantes econômicos a esta viabilidade. Por fim, o processo de projeto desenvolvido pode servir de auxílio a novos projetistas na área. / The high energy consumption in buildings for their thermal conditioning is already one of the greatest environmental impacts of civil construction in developed countries and, progressively, is also becoming a concern in the developing countries. A relatively recent renewable alternative, as much for heating as for cooling, are the ground source heat pumps, GSHPs, which take advantage of the thermal inertia of the ground to significantly decrease the energy demand comparing to air as a source. In spite of their huge potential for decreasing energy comsumption and carbon emissions, this technology is still almost inexistent in Latin America, due not only to lack of awareness, but mainly to uncertainties about their feasibility because of their higher investment cost. Although there are many researches about the characteristics and operation of GSHPs, great part of the practical knowledge as to the design, performance and feasibility is based in the experience from the first countries where the technology spreaded, and cannot be automatically assumed as valid without a previous evaluation. Former studies indicated that the economic profit of GSHPs tends to be higher in colder climates, while the efficiency tends to be higher in milder, but still seasonal climates. For presenting a good balance among these factors, the Rio Grande do Sul State shows potential for a high performance of GSHPs The objective of this work is to estimate the efficiency levels that can be reached by this technology in a reference city in the State, as its financial feedback compared to ASHPs (air source heat pumps, the traditional air conditioners, or A/C), its limitations and the design difficulties. A residential single-family building in Porto Alegre, specifically designed for sustainability studies, was used as case study for the complete conceptual design of a vertical GSHP, a horizontal GSHP and an ASHP. The energy demand and operation and installation costs for specific conditions were estimated and compared in a economic feasibility study. After, the results were extrapolated through a sensitivity analysis for more generic situations of consumption. Through the calculations, it was observed that the technology achieved twice the efficiency of the most efficient A/C available for the case study. Economically, the technology showed itself viable, and economic limitations were also estimated. At last, the developed design process can also serve as aid to new designers in the field.

O elevado consumo energético de edificações para o seu condicionamento térmico já é um dos maiores impactos ambientais da construção civil nos países desenvolvidos e, progressivamente, vem se tornando uma preocupação também nos países em desenvolvimento. Uma alternativa renovável relativamente recente, tanto para aquecimento como para resfriamento, são as bombas de calor geotérmicas (ground source heat pumps, GSHPs), que se valem da inércia térmica do solo para reduzir significativamente a demanda energética em relação ao ar. Apesar do seu grande potencial em reduzir o consumo de energia e as emissões de carbono, esta tecnologia ainda é quase inexistente na América Latina, não somente devido à falta de conhecimento ao seu respeito, mas também pela incerteza quanto à sua viabilidade frente a um custo inicial mais elevado. Embora existam muitas pesquisas sobre o funcionamento de GSHPs, grande parte do conhecimento prático quanto ao projeto, desempenho e viabilidade é baseada na experiência dos primeiros países onde a tecnologia começou a se tornar popular, e não pode ser assumida automaticamente como válida em outras situações sem uma avaliação prévia Estudos anteriores apontaram que o retorno econômico de GSHPs tende a ser maior em climas mais frios, enquanto a eficiência tende a ser maior em climas mais amenos, mas com sazonalidade. Por apresentar um bom balanço destas características, o Estado do Rio Grande do Sul apresenta potencial para um desempenho elevado de GSHPs. O objetivo deste trabalho é estimar os níveis de eficiência que esta tecnologia pode atingir em uma cidade de referência no Estado, assim como seu retorno econômico frente a ASHPs (air source heat pumps, ou seja, aparelhos de ar condicionado, ou A/C), seus limitantes e as dificuldades de projeto. Uma edificação unifamiliar residencial em Porto Alegre, projetada especialmente para estudos de sustentabilidade, foi utilizada como caso de estudo para o projeto conceitual completo de um GSHP vertical, um GSHP horizontal e um ASHP. Foram estimadas a demanda de energia e os custos de operação e de implantação para determinadas condições, que foram comparadas em um estudo de viabilidade econômica. Após, os resultados foram extrapolados por uma análise de sensitividade para condições mais genéricas de consumo. Através dos cálculos, observou-se que a tecnologia de GSHPs atingiu o dobro da eficiência dos A/C mais eficientes disponíveis para o caso de estudo. Economicamente, a tecnologia também se mostrou viável, e foram estimados limitantes econômicos a esta viabilidade. Por fim, o processo de projeto desenvolvido pode servir de auxílio a novos projetistas na área. / The high energy consumption in buildings for their thermal conditioning is already one of the greatest environmental impacts of civil construction in developed countries and, progressively, is also becoming a concern in the developing countries. A relatively recent renewable alternative, as much for heating as for cooling, are the ground source heat pumps, GSHPs, which take advantage of the thermal inertia of the ground to significantly decrease the energy demand comparing to air as a source. In spite of their huge potential for decreasing energy comsumption and carbon emissions, this technology is still almost inexistent in Latin America, due not only to lack of awareness, but mainly to uncertainties about their feasibility because of their higher investment cost. Although there are many researches about the characteristics and operation of GSHPs, great part of the practical knowledge as to the design, performance and feasibility is based in the experience from the first countries where the technology spreaded, and cannot be automatically assumed as valid without a previous evaluation. Former studies indicated that the economic profit of GSHPs tends to be higher in colder climates, while the efficiency tends to be higher in milder, but still seasonal climates. For presenting a good balance among these factors, the Rio Grande do Sul State shows potential for a high performance of GSHPs The objective of this work is to estimate the efficiency levels that can be reached by this technology in a reference city in the State, as its financial feedback compared to ASHPs (air source heat pumps, the traditional air conditioners, or A/C), its limitations and the design difficulties. A residential single-family building in Porto Alegre, specifically designed for sustainability studies, was used as case study for the complete conceptual design of a vertical GSHP, a horizontal GSHP and an ASHP. The energy demand and operation and installation costs for specific conditions were estimated and compared in a economic feasibility study. After, the results were extrapolated through a sensitivity analysis for more generic situations of consumption. Through the calculations, it was observed that the technology achieved twice the efficiency of the most efficient A/C available for the case study. Economically, the technology showed itself viable, and economic limitations were also estimated. At last, the developed design process can also serve as aid to new designers in the field.

Flow mechanisms of compound meandering channels are recognised to be far more complicated than compound straight channels. The compound meandering channels are mainly characterised by the continuous variation of mean and turbulent flow parameters along a meander wavelength; the existence of horizontal shear layer at the bankfull level and the presence of strong helical secondary flow circulations in the streamwise direction. The secondary flow circulations are very important as they govern the advection of flow momentum, distort isovels, and influence bed shear stress, thus producing a complicated and fully three-dimensional turbulent flow structures. A great deal of experiments has been conducted in the past, which explains flow mechanisms, mixing patterns and the behaviour of secondary flow circulations. However, a complete understanding of secondary flow structures still remains far from conclusive mainly because the secondary flow structures are influenced by the host of geometrical and flow parameters, which are yet to be investigated in detail. The three-dimensional Reynolds-averaged Navier-Stokes and continuity equations were solved using a standard Computational Fluid Dynamics solver to predict mean velocity, secondary flow and turbulent kinetic energy. Five different flow cases of various model scales and relative depths were considered. Detailed analyses of the measured and predicted flow variables were carried out to understand mean flow mechanisms and turbulent secondary flow structures in compound meandering channels. The streamwise vorticity equation was used to quantify the complex and three-dimensional behaviour of secondary flow circulations in terms of their generation, development and decay along the half-meander wavelength. The turbulent kinetic energy equation was used to understand energy expense mechanisms of secondary flow circulations. The strengths of secondary flow circulations were calculated and compared for different flow cases considered. The main findings from this research are as follows. The shearing of the main channel flow as the floodplain flow plunges into and over the main channel influences the mean and turbulent flow structures particularly in the crossover region. The horizontal shear layer at the inner bankfull level generates secondary flow circulations. As the depth of flow increases, the point of generation of secondary flow circulations moves downstream. The secondary shear stress significantly contributes towards the generation of streamwise vorticity and the production of turbulent kinetic energy. The rate of turbulence kinetic energy production was found to be higher than the rate of its dissipation in the crossover region, which demonstrates that the turbulence extracts more energy from the mean flu\\' than what is actually dissipated. This also implies that, in the crossover region, the turbulence is always advected downstream by the mean and secondary flows, The strength of geometry induced secondary flow circulation increases with the increase in the relative depth.

O elevado consumo energético de edificações para o seu condicionamento térmico já é um dos maiores impactos ambientais da construção civil nos países desenvolvidos e, progressivamente, vem se tornando uma preocupação também nos países em desenvolvimento. Uma alternativa renovável relativamente recente, tanto para aquecimento como para resfriamento, são as bombas de calor geotérmicas (ground source heat pumps, GSHPs), que se valem da inércia térmica do solo para reduzir significativamente a demanda energética em relação ao ar. Apesar do seu grande potencial em reduzir o consumo de energia e as emissões de carbono, esta tecnologia ainda é quase inexistente na América Latina, não somente devido à falta de conhecimento ao seu respeito, mas também pela incerteza quanto à sua viabilidade frente a um custo inicial mais elevado. Embora existam muitas pesquisas sobre o funcionamento de GSHPs, grande parte do conhecimento prático quanto ao projeto, desempenho e viabilidade é baseada na experiência dos primeiros países onde a tecnologia começou a se tornar popular, e não pode ser assumida automaticamente como válida em outras situações sem uma avaliação prévia Estudos anteriores apontaram que o retorno econômico de GSHPs tende a ser maior em climas mais frios, enquanto a eficiência tende a ser maior em climas mais amenos, mas com sazonalidade. Por apresentar um bom balanço destas características, o Estado do Rio Grande do Sul apresenta potencial para um desempenho elevado de GSHPs. O objetivo deste trabalho é estimar os níveis de eficiência que esta tecnologia pode atingir em uma cidade de referência no Estado, assim como seu retorno econômico frente a ASHPs (air source heat pumps, ou seja, aparelhos de ar condicionado, ou A/C), seus limitantes e as dificuldades de projeto. Uma edificação unifamiliar residencial em Porto Alegre, projetada especialmente para estudos de sustentabilidade, foi utilizada como caso de estudo para o projeto conceitual completo de um GSHP vertical, um GSHP horizontal e um ASHP. Foram estimadas a demanda de energia e os custos de operação e de implantação para determinadas condições, que foram comparadas em um estudo de viabilidade econômica. Após, os resultados foram extrapolados por uma análise de sensitividade para condições mais genéricas de consumo. Através dos cálculos, observou-se que a tecnologia de GSHPs atingiu o dobro da eficiência dos A/C mais eficientes disponíveis para o caso de estudo. Economicamente, a tecnologia também se mostrou viável, e foram estimados limitantes econômicos a esta viabilidade. Por fim, o processo de projeto desenvolvido pode servir de auxílio a novos projetistas na área. / The high energy consumption in buildings for their thermal conditioning is already one of the greatest environmental impacts of civil construction in developed countries and, progressively, is also becoming a concern in the developing countries. A relatively recent renewable alternative, as much for heating as for cooling, are the ground source heat pumps, GSHPs, which take advantage of the thermal inertia of the ground to significantly decrease the energy demand comparing to air as a source. In spite of their huge potential for decreasing energy comsumption and carbon emissions, this technology is still almost inexistent in Latin America, due not only to lack of awareness, but mainly to uncertainties about their feasibility because of their higher investment cost. Although there are many researches about the characteristics and operation of GSHPs, great part of the practical knowledge as to the design, performance and feasibility is based in the experience from the first countries where the technology spreaded, and cannot be automatically assumed as valid without a previous evaluation. Former studies indicated that the economic profit of GSHPs tends to be higher in colder climates, while the efficiency tends to be higher in milder, but still seasonal climates. For presenting a good balance among these factors, the Rio Grande do Sul State shows potential for a high performance of GSHPs The objective of this work is to estimate the efficiency levels that can be reached by this technology in a reference city in the State, as its financial feedback compared to ASHPs (air source heat pumps, the traditional air conditioners, or A/C), its limitations and the design difficulties. A residential single-family building in Porto Alegre, specifically designed for sustainability studies, was used as case study for the complete conceptual design of a vertical GSHP, a horizontal GSHP and an ASHP. The energy demand and operation and installation costs for specific conditions were estimated and compared in a economic feasibility study. After, the results were extrapolated through a sensitivity analysis for more generic situations of consumption. Through the calculations, it was observed that the technology achieved twice the efficiency of the most efficient A/C available for the case study. Economically, the technology showed itself viable, and economic limitations were also estimated. At last, the developed design process can also serve as aid to new designers in the field.

The master’s thesis deals with computational modelling of mechanical testing of isolated cells, particularly of single-axle tensile test. The aim is to imitate the real deformed shape known from experiments. At first, the structure of each cell component is described and analyzed according to their significance for mechanical behavior. The outline of basic mechanical tests used for cell testing is discussed next. A structural computational model comprising all components significant for mechanical purposes is created for the modelling. Those components are nucleus, cytoplasm, cell membrane and cytoskeleton. Due to the problems with convergence the model was divided into two parts. The first one treats separately the shape of cytoskeleton and the second one treats the shape of communicating components (nucleus, cytoplasm and cell membrane). Both of those partial models succeed in reaching the deformations according to the experiments.

Non-union bone fractures are a standing problem for clinical treatments. It has been found that the exogenous growth factor recombinant human bone morphogenetic protein-2 (rhBMP-2) induces bone healing in potential non-union fractures. However, the currently used clinical dose of rhBMP-2 is high and causes side-effects. Mechanical loading is known to enhance the induced effects of rhBMP-2 in bone healing, which may lead to a reduced required dose. Yet, the exact underlying mechanism is unknown. To further investigate the combined role of mechanical loading and rhBMP-2 in the early phase of fracture healing a 2D computational model was developed. The model uses a lattice-based approach where biological rule-based events are combined with finite element analysis to simulate both untreated bone healing progression and when subjected to mechanical loading and rhBMP-2. Two healing cases were investigated:  normal fracture healing in a small bone defect (1 mm gap) and non-union fracture healing in a large bone defect (5 mm gap). By varying the magnitude and timing of applied load as well as the rhBMP-2 dose, a combination that would reduce the currently used rhBMP-2 dose and still enable healing in a large bone defect was searched. The model could simulate fracture healing in a large bone defect when subjected to rhBMP-2, independently of the applied load. Also the expected non-union result in a large bone defect without applied rhBMP-2 was obtained. The model could not capture normal fracture healing in a small bone defect as well as bone remodelling. It was found that a 50 % reduced rhBMP-2 dose could not induce healing in a large bone defect when applied separately but when applied together with load. Additionally, this combination of stimulation gave similar results compared to other combinations using higher rhBMP-2 doses. To conclude, even though the model was able to replicate some of the healing events seen experimentally, it is in need of modifications to correct current deficiencies. Still, after some further development and validation, the model has the potential to be used in future studies of fracture healing when influenced by mechanical loading and rhBMP-2. The found possibility for a reduced dosage of rhBMP-2 when applied together with load has to be further investigated before any conclusions can be drawn.

No description available.

No / Trust management in mobile ad hoc networks (MANETs) has become a significant issue in securing routing protocols to choose reliable and trusted paths. Trust is used to cope with defection problems of nodes and stimulate them to cooperate. However, trust is a highly complex concept because of the subjective nature of trustworthiness, and has several social properties, due to its social origins. In this paper, a friendship-based trust model is proposed for MANETs to secure routing protocol from source to destination, in which multiple social degrees of friendships are introduced to represent the degree of nodes' trustworthiness. The model considers the behaviour of nodes as a human pattern to reflect the complexity of trust subjectivity and different views. More importantly, the model considers the dynamic differentiation of friendship degree over time, and utilises both direct and indirect friendship-based trust information. The model overcomes the limitation of neglecting the social behaviours of nodes when evaluating trustworthiness. The empirical analysis shows the greater robustness and accuracy of the trust model in a dynamic MANET environment.

Online services such as e-marketplaces, social networking sites, online gaming environments etc have grown in popularity in the recent years. These services represent situation where participants do not get to negotiate face to face before interaction and most of the time parties to transaction remain anonymous. It is thus necessary to have a system that rightly assesses trustworthiness of the other party in order to maintain quality assurance in such systems. Recent works on Trust and Reputation in online communities have focused on identifying probable defaulters, but less effort has been put to come up with system that make cooperation attractive over defection in order to achieve cooperation without enforcement. Our work in this regard concerns design and investigation of trust assessment systems that not only filter defaulters but also promote evolution of cooperativeness in player society. Based on the concept of game theory and prisoner¿s dilemma, we model business games and design incentive method, compensation method, acquaintance based assessment method and decision theoretic assessment method as mechanisms to assure trustworthiness in online business environments. Effectiveness of each of these methods in promoting the evolution of cooperation in player society has been investigated. Our results show that these methods contribute positively in promoting cooperative evolution. We have further extended our trust assessment model to suit the needs of a mobile ad-hoc network setting. The effectiveness of this model has been tested against its capability to reduce packet drop rate and energy conservation. In both of these the results show promise. / EU Asia-link project TH/Asia Link/004(91712) East-West and its local host Kantipur Engineering College in Nepal, and Kathmandu University.

No / Cloud computing is increasingly attracting large attention both in academic research and in industrial initiatives. However, despite the popularity, there is a lack of research on the suitability of software tools and parameters for creating and deploying Cloud test beds. Virtualization and how to set up virtual environments can be done through software tools, which are available as open source, but there still needs to be work in terms of which tools to use and how to monitor parameters with the suitability of hardware resources available. This paper discusses the concepts of virtualization, as a practical view point, presenting an in-depth critical analysis of open source cloud implementation tools such as CloudStack, Eucalyptus, Nimbus, OpenStack, OpenNebula, OpenIoT, to name a few. This paper analyzes the various toolkits, parameters of these tools, and their usability for researchers looking to deploy their own Cloud test beds. The paper also extends further in developing an experimental case study of using OpenStack to construct and deploy a test bed using current resources available in the labs at the University of Bradford. This paper contributes to the theme of software setups and open source issues for developing Cloud test bed for deploying and constructing private Cloud test bed.