This thesis proposes an advanced architecting methodology. This methodology allows for the sizing and optimization of aircraft system architecture concepts and the establishment of subsystem development strategies. The process is implemented by an architecting team composed of subsystem experts and architects. The methodology organizes the architecture definition using the SysML language. Using meta-modeling techniques, this definition is translated into an analysis model which automatically integrates subsystem analyses in a fashion that represents the specific architecture concept described by the team. The resulting analysis automatically sizes the subsystems composing it, synthesizes their information to derive architecture-level performance and explores the architecture internal trade-offs. This process is facilitated using the Coordinated Optimization method proposed in this dissertation. This method proposes a multi-level optimization setup. An architecture-level optimizer orchestrates the subsystem sizing optimizations in order to optimize the aircraft as whole. The methodologies proposed in this thesis are tested and demonstrated on a proof of concept based on the exploration of turbo-electric propulsion aircraft concepts.