In this study reef corals from two Caribbean and adjacent regions in different periods were investigated. Sclerochronological records of corals from well preserved Miocene to Pleistocene reefs were used to document potential changes in seasonal and interannual climate associated with CAS uplift and closure. In southern Florida the Plio/Pleistocene Caloosahatchee Formation is cropping out. During the deposition of this stacked shallow marine sediments at the Plio/Pleistocene Florida carbonate platform, a rich coral fauna existed. Corals from the Caloosahatchee Formation were investigated herein, regarding to reveal high resolution (bimonthly) climatic archives in their skeletons. The second region investigated herein is the Cibao Valley in the Dominican Republic, where sediments of the Neogene Yaque Group are outcropping. Corals from the Late Miocene Cercado Formation and the Mio/Pliocene Gurabo Formation (both upper part of the Yaque Group) are discussed here. Both formations are mixed carbonate-siliciclastic deposits of the prograding inner-shelf and contain a well preserved faunal record. Sclerochronological methods are used to identify seasonal and interannual climatic variability. Especially radiography, stable isotope analysis and laser ablation measurements (LA-ICP-MS) were used and discussed with a special focus on the pristine preservation of the analysed coralline material.