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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Deriving Genetic Networks from Gene Expression Data and Prior Knowledge

Lindlöf, Angelica January 2001 (has links)
In this work three different approaches for deriving genetic association networks were tested. The three approaches were Pearson correlation, an algorithm based on the Boolean network approach and prior knowledge. Pearson correlation and the algorithm based on the Boolean network approach derived associations from gene expression data. In the third approach, prior knowledge from a known genetic network of a related organism was used to derive associations for the target organism, by using homolog matching and mapping the known genetic network to the related organism. The results indicate that the Pearson correlation approach gave the best results, but the prior knowledge approach seems to be the one most worth pursuing
2

Deriving Genetic Networks from Gene Expression Data and Prior Knowledge

Lindlöf, Angelica January 2001 (has links)
<p>In this work three different approaches for deriving genetic association networks were tested. The three approaches were Pearson correlation, an algorithm based on the Boolean network approach and prior knowledge. Pearson correlation and the algorithm based on the Boolean network approach derived associations from gene expression data. In the third approach, prior knowledge from a known genetic network of a related organism was used to derive associations for the target organism, by using homolog matching and mapping the known genetic network to the related organism. The results indicate that the Pearson correlation approach gave the best results, but the prior knowledge approach seems to be the one most worth pursuing</p>

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