Spelling suggestions: "subject:"cortical circuit"" "subject:"acortical circuit""
1 |
Functional connectivity of layer II/III and V GABAergic Martinotti cells in the primary somatosensory (barrel) cortex of miceWalker, Florian 10 February 2016 (has links)
No description available.
|
2 |
Elektrophysiologische Charakterisierung GABA-Rezeptoren vermittelter Inhibition an Martinotti-Zellen im somatosensorischen Kortex / Electrophysiological characterization of GABA receptor-mediated inhibition on Martinotti cells in the somatosensory cortexDelchmann, Jürgen 17 January 2018 (has links)
No description available.
|
3 |
Task-specific modulation of corticospinal excitability during arm and finger movementsAsmussen, Michael James 28 May 2015 (has links)
The main goal of the dissertation was to determine task-dependent modulation of corticospinal descending output. From this main goal, I conducted three different studies to determine how corticospinal output to muscles of the upper arm and hand changed as a function of the task demands. In study 1, I examined how a somatosensory-motor circuit changes when a muscle needs to be active in a task and found that this circuit may be dependent on the movement phase, type of afferent input, and the task demands. In study 2, I examined how this same somatosensory-motor circuit acts to both allow and prevent muscle activity before movement. I revealed that this somatosensory-motor circuit may function to prevent muscle activity when a muscle is not needed in a task and creates facilitation of corticospinal output when it needs to be active in a task. These effects, however, are dependent on the movement phase and the digit the muscle is controlling. Study 3 determined how corticospinal output is modulated to upper arm muscles when performing movements that required different combinations of segmental interactions to achieve the task successfully. Corticospinal output was increased when inertia and the BBC moment at a joint resisted the intended joint rotation and these effects were dependent on the muscle and movement phase. I propose a model of the connectivity between the primary motor and somatosensory cortices that would increase, modulate, or decrease corticospinal output to a muscle depending on its role in the task. The findings from this work provides information to guide future neural rehabilitative interventions for individuals who have movement disorders arising from altered somatosensory-motor processing such as Cerebellar Ataxia, Developmental Coordination Disorder, Focal Hand Dystonia, Parkinson’s disease, and stroke. / Dissertation / Doctor of Philosophy (PhD) / On a day to day basis, we perform a variety of movements without giving much thought to how complicated it is for our nervous system to perform said movements. There are many different areas of the brain that are responsible for controlling movement. This dissertation focuses on two key areas that are critical for movement performance, namely the primary motor and somatosensory cortices. The primary motor cortex is largely responsible for sending signals to the muscles to control movement, while the primary somatosensory cortex plays a crucial role in receiving and understanding sensory input from our body. The studies in this dissertation describe how these two areas of the brain communicate during finger and arm movements to produce or prevent muscle activity. This work has implications for individuals with disorders that impact their everyday movements.
|
Page generated in 0.0468 seconds