- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 351 to 360 of 23271 (0.025 seconds)| 351 |
An investigation into the virulence components of Neisseria meningitidisMacKinnon, Fiona Gwynneth January 1994 (has links)
No description available.
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| 352 |
Molecular analysis of the Huntingdon's disease gene region in man and pufferfishBaxendale, Sarah January 1995 (has links)
No description available.
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| 353 |
Investigation of the structure and function of the PKD domain of polycystin-1, the protein product of the PKD1 geneCase, Ruth January 2002 (has links)
No description available.
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| 354 |
A molecular study of virulence factors of Bordetella speciesLi, Jing-Li January 1990 (has links)
A 1kb HinfI DNA fragment, containing a repeat DNA sequence element was isolated from a Bordetella pertussis BP348 cosmid gene bank. This repeat DNA sequence has subsequently been named IS148. The insertion sequence was demonstrated by have a high copy number only in B.pertissus and to be absent in Bordetella parapertussis and Bordetella bronchiseptica. Using a restriction fragment of IS148 labelled with radioactivity as a probe in DNA or whole cell dot blots between 10-100 cells could be detected or from 100pb-1ng DNA. Furthermore, a pair of oligonucleotide primers was synthesised corresponding to a central region of IS148 that could generate a 242bp fragment upon PCR amplification. The use of PCR amplification with specific primers allows the detection of 0.5pg of B.pertussis chromosomal DNA and as little as one B.pertussis cell. The prn genes encoding the outer membrane P.70 and P.68 pertactin from B.parapertussis and B.bronchiseptica have been cloned, sequenced and expressed in Escherichia coli. Analysis of the DNA sequences reveal that the genes have open reading frames capable of encoding proteins with molecular weights of 95,177 (P.95, B.parapertussis) and 93,996 (P.94, B.bronchiseptica). These precursors molecular are processed to form the P.70 and P.68 antigens on the surface of B.parapertussis and B.bronchiseptica respectively. Heterologous expression of the full-length gene encoding P.95 and P.94 in E.coli result in similar processing, with the P.70 and P.68 antigens targetted to the bacterial outer membrane. Comparison of P.95, P.94 and P.93, encoding homologous proteins from B.parapertussis, B.bronchiseptica and B.pertussis, shows a high degree (> 90%) of homology. The major differences between all three proteins occur in the number of repeat of the two families (Gly-Gly-Xaa-Xaa-Pro)n and (Pro-Gln-Pro)n of reiterated sequence motifs.
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| 355 |
Variation in the PorA protein, and clonal diversity within the UK Neisseria meningitidis population over a twenty year period (1975-1995)Russell, Joanne January 2001 (has links)
No description available.
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| 356 |
The human homologue of the murine glomerulosclerosis gene Mpv17Zwacka, Ralf Michael January 1995 (has links)
No description available.
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| 357 |
Immune effector mechanisms in equine herpesvirus type-1 infectionStokes, A. January 1988 (has links)
No description available.
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| 358 |
The role of polyamines in motor behaviourDevadasan, Carol January 2001 (has links)
No description available.
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| 359 |
Qualitative and quantitative studies on infection of E. Hungarensis (Levine & Ivens, 1965) in the wood mouse Apodemus Sylvaticus and labaratory mouse Mus musculusArab, Fahad Ahmad H. January 1992 (has links)
No description available.
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| 360 |
Botrytis cinerea tubulin and its use in the development of an immunodiagnostic test for benzimidazole fungicide resistanceGroves, J. D. January 1989 (has links)
No description available.
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