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Synthesis and characterization of a DNA ligase : towards two stage replication /Ye, Jingdong. January 2001 (has links)
Thesis (Ph. D.)--University of Chicago, Dept. of Chemistry, 2002. / Includes bibliographical references (p. 157-158). Also available on the Internet.
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Mismatch ligation during non-homologous end joining pathway kinetic characterization of human DNA ligase IV/XRCC4 complex /Wang, Yu. January 2007 (has links)
Thesis (Ph. D.)--Ohio State University, 2007. / Full text release at OhioLINK's ETD Center delayed at author's request
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An analysis of vaccinia virus DNA ligaseOdell, Mark January 1996 (has links)
No description available.
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Discrimination of RNA versus DNA by an RNA ligase and distinct modes of substrate recognition by DNA ligases /Nandakumar, Jayakrishnan. January 2007 (has links)
Thesis (Ph. D.)--Cornell University, May, 2007. / Vita. Includes bibliographical references (leaves 324-341).
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A functional analysis of the mammalian E3 ubiquitin ligase WWP1 in a yeast modelSankaran, Saumya M. January 2009 (has links)
Thesis (M.S.)--Brandeis University, 2009. Senior honors thesis--Brandeis University, 2009. / Title from PDF title page (viewed on June 29, 2009). Includes bibliographical references.
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The intracellular localization of mammalian DNA ligase IBarker, Sharon. January 1996 (has links)
DNA replication is cruciaI for the transmission of genetic information. Understanding the enzymology involved in this complex process will allow further insight into its mechanism. Experimental evidence indicates a role for DNA ligase I in DNA replication. Techniques of molecular and cellular biology and immunology were utilized in this study to further investigate DNA ligase I and clarify its involvement and interaction with other proteins in DNA replication. Immunofluorescence studies were performed to examine the intracellular distribution of DNA ligase I. Confocal analysis of indirect immunofluorescence detection of DNA ligase I using affinity purified anti-human DNA ligase I antibodies showed nuclear localization of DNA ligase I in distinct foci resembling those structures seen in detection of centres of DNA replication and other DNA replication proteins. Immunoprecipitation experiments were performed on extracts of MDBK cells to examine possible interactions of DNA ligase I with the DNA replication cofactor, PCNA; and no interactions were detected.
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ENU mouse mutant with a hypomorphic mutation in DNA ligase IVNijnik, A. January 2006 (has links)
No description available.
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Characterization of DNA and RNA end modifying enzymes and a triphosphate tunnel metalloenzyme /Keppetipola, Niroshika. January 2009 (has links)
Thesis (Ph. D.)--Cornell University, January, 2009. / Vita. Includes bibliographical references (leaves 264-277).
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The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends /Aniukwu, Jideofor Flint. January 2008 (has links)
Thesis (Ph. D.)--Cornell University, May, 2008. / Vita. Includes bibliographical references (leaves 125-133).
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Error-prone DNA repair in the African swine fever virus characterization of six abasic site processing activities and evidence for a mutagenic function /Lamarche, Brandon James. January 2005 (has links)
Thesis (Ph. D.)--Ohio State University, 2005. / Available online via OhioLINK's ETD Center; full text release delayed at author's request until 2006 Jun 1.
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