Global ETD Search

31	Biochemical and biophysical characterisation of the domain structure of the HsdS subunit of EcoR124I Smith, Melanie Anne January 2000 (has links) No description available. 572
32	Transcription regulation of hepatotoxins microcystin and nodularin from cyanobacteria Root, Hannah Patricia, Biotechnology & Biomolecular Sciences, Faculty of Science, UNSW January 2008 (has links) The role and function of hepatotoxins microcystin and nodularin produced by M.aeruginosa PCC 7806 and N. spumigena NSORlO respectively have yet to be elucidated. The mode of transcriptional regulation of these toxins, incorporating DNA binding proteins, was investigated, as an attempt to further understand the key control mechanisms acting on the toxins. The DNA binding proteins that control nitrogen and iron responsive transcription, NtcA and Fur, were identified from M. aeruginosa PCC7806 and N. spumigena NSOR10. Cloning and over-expression in E. coli was followed by mobility shift assays to determine binding characteristics of NtcA and Fur to the promoters, mcyA/D and ndaA/C, those regions that control the toxin encoding gene clusters in M. aeruginosa PCC 7806 and N. spumigena NSOR10, respectively. The results from these studies suggested a role for iron and nitrogen in the transcriptional control of microcystin and nodularin. biosynthesis. As NtcA and Fur classically act to regulate nitrogen and iron dependent genes, a link may be made to the putative function and control of microcystin and nodularin. By identifying the transcription factors NtcA and Fur in these genera, a greater understanding of the link between nutrient levels in the environment and hepatotoxin production in cyanobacteria may be possible. Microcystin. Hepatotoxins. DNA binding proteins. Nodularin. Cyanobacteria.
33	Studying the roles of conserved domains of the transcription factor Sox10 in neural crest development Chee, Ming-chu, Daisy. January 2008 (has links) Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 96-106) Also available in print.
34	Development and characterization of a new assay to examine telomere-protein interactions in vivo / Bourns, Brenda, January 1997 (has links) Thesis (Ph. D.)--University of Washington, 1997. / Vita. Includes bibliographical references (leaves [116]-123).
35	Advancement of the timing of origin activation by a cis-acting DNA element / Kolor, Katherine, January 1997 (has links) Thesis (Ph. D.)--University of Washington, 1997. / Vita. Includes bibliographical references (leaves [137]-147).
36	Investigations at the molecular interfaces of complexes formed by the proteins ADR1 and xUBF1 with DNA / Fischhaber, Paula L. January 1998 (has links) Thesis (Ph. D.)--University of Washington, 1998. / Vita. Includes bibliographical references (leaves [89]-94).
37	Transcriptional regulation of the human small nuclear RNA gene family Jawdekar, Gauri W. January 2006 (has links) Thesis (Ph. D.)--Michigan State University. Dept. of Microbiology and Molecular Genetics, 2006. / Title from PDF t.p. (viewed on June 19, 2009) Includes bibliographical references. Also issued in print.
38	Functional characterization of the novel a/t-rich interaction domain member, Brightlike (ARID3C) Curcio, Josephine Antonette, January 1900 (has links) Thesis (Ph. D.)--University of Texas at Austin, 2008. / Vita. Includes bibliographical references.
39	DNA binding proteins of archaeal viruses Geary, Joella Suzanne. January 2008 (has links) (PDF) Thesis (MS)--Montana State University--Bozeman, 2008. / Typescript. Chairperson, Graduate Committee: Mensur Dlakic. Includes bibliographical references (leaves 56-61).
40	DNA-Dependent ATPase A : overexpression and characterization of the ATP hydrolyzing domain of the enzyme and identification of a novel class of inhibitors specific for this domain / Muthuswami, Rohini. January 1998 (has links) Thesis (Ph. D.)--University of Virginia, 1998. / Includes bibliographical references (p. 314-323). Also available online through Digital Dissertations.

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