Global ETD Search

51	iSpace : a personal design environment within a virtual space Smaglick, Christopher Richard 12 1900 (has links) No description available. Virtual reality Architectural design Data processing Space (Architecture)
52	ND, a rule-based implementation of natural deduction : design of the theorem-prover and tutoring system Dongier, François January 1988 (has links) No description available. Computer-assisted instruction. Logic in teaching. Logic design -- Data processing.
53	Design procedures for self-supporting transmission towers. Hanna, Albert William Ghabbour. January 1971 (has links) No description available. Electric power distribution Structural design Structural design -- Data processing.
54	Pseudo-affine functions : a non-polynomial implicit function family to describe curves and sufaces Akleman, Ergun 08 1900 (has links) No description available. Geometric drawing Data processing Engineering mathematics Engineering design Data processing
55	The complementary roles of expert systems and database management systems in a design for manufacture environment Miller, Garth Soren 05 1900 (has links) No description available. Engineering design Data processing Production design Expert systems (Computer science)
56	A concept exploration method for product family design Simpson, Timothy W. 12 1900 (has links) No description available. New products Production engineering Engineering design Data processing
57	Interfacing geometric design models to analyzable product models with multifidelity and mismatched analysis geometry Chandrasekhar, Ashok 12 1900 (has links) No description available. Geometry Data processing Computer-aided design Engineering design Data processing
58	An introduction of a decision table language (DTL) as an ICES subsystem Butalla, Martin William 12 1900 (has links) No description available. Engineering design Data processing Decision logic tables Computer programs
59	Quantity take-offs during design by the use of CAD Dull, Christopher G. 08 1900 (has links) No description available. Architecture Data processing Computer-aided design Architectural design Data processing
60	Computational antiviral drug design / Alternate title from signature form: Computational antiviral drug discovery Clifton, Heather A. January 2009 (has links) The goal of this research is to identify a compound or family of compounds that would allow effective treatment of the influenza virus without unnecessary risks and side-effects. Influenza is a substantial problem in today’s society. Each year 36,000 people die in the United States due to influenza, or influenza related causes. Influenza is caused by two types of the virus, Type-A and Type-B. There are currently four FDA approved drugs to treat influenza—two are proton channel blockers and two are neuraminidase inhibitors. The goal of my research was to design a new drug that would allow physicians to effectively treat Type-A and Type-B influenza virus without having their patients endure unnecessary risks and side-effects. Density functional theory calculations were used to optimize the geometries of the ligands. Using sophisticated resources such as the Protein Data Bank and AutoDock, a library of twenty five ligands were docked into the N4 protein. Each docking was performed five times, resulting in one overall average docked energy. The averaged energies for each of the ligands were ranked from lowest to highest. Based upon a different study, one of my ligands were shown to have antiviral activity. From the docked energy for the ligand with confirmed antiviral activity, the results of the highest ranking ligand could be determined to have promising antiviral activity. The ligand shown below is the promising ligand, which will undergo further alterations and dockings to attempt to improve the antiviral activity. / Department of Chemistry Antiviral agents Design Data processing Ligands (Biochemistry) Influenza-Treatment

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