Global ETD Search

11	Rapid assessment of drug susceptibility and mutation to resistance in mycobacterium tuberculosis Beijing type / Werngren, Jim, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2006. / Härtill 5 uppsatser.
12	Carbapenem resistance in Pseudomonas aeruginosa / Giske, Christian G., January 2007 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 5 uppsatser.
13	Defense peptides against Mycobacteria / Linde, Charlotte M. A., January 2005 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 4 uppsatser.
14	Studies on the molecular mechanisms of resistance to fluoroquinolones and carbapenems in selected bacterial species / El Amin, Nagwa Mustafa, January 2003 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 5 uppsatser.
15	Bacterial adaptation to novel selection pressures / Nilsson, Annika, January 2005 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 5 uppsatser.
16	Population structure and antibiotic resistance of the genus enterococcus in humans, animals and the environment / Iversen, Aina, January 2005 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 6 uppsatser.
17	Antibiotic resistance and antibiotic consumption in Sweden with focus on Escherichia coli and Pseudomonas aeruginosa / Farra, Anna, January 2007 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
18	Interactions of oral spirochetes with the innate immune mechanisms of the gingival epithelium / Brissette, Catherine Ayn. January 2006 (has links) Thesis (Ph. D.)--University of Washington, 2006. / Vita. Includes bibliographical references (leaves 111-134).
19	Analysis and studies of inhibition of the two divergent thymidine biosynthesis pathways in Mycobacterium tuberculosis / Ulmer, Jonathan Edward, January 2007 (has links) Thesis (Ph. D.)--University of Washington, 2007. / Vita. Includes bibliographical references (leaves 186-200).
20	Perfil de resistência do Mycobacterium Tuberculosis de pacientes internados em um hospital de referência do estado de São Paulo / Rodrigues, Ana Rachel de Seni. January 2017 (has links) Orientador: Fernando Rogerio Pavan / Banca: Daisy Nakamura Sato / Banca: Rodolpho Teralolli Junior / Resumo: Apesar da incidência da Tuberculose (TB) ter diminuído nos últimos anos, nota-se um expressivo aumento dos casos de TBMDR (multi-fármaco-resistente) e TBXDR (extensivamente-fármaco-resistente). A situação constitui um sério problema de saúde pública no mundo e no Brasil, com menor taxa de cura, pior prognóstico e nenhum tratamento de eficácia comprovada para contatos. A taxa estimada de cura global para TBMDR é de 52% e para TBXDR, os desfechos são ainda menos favoráveis. Nesse sentido, buscamos nesse trabalho determinar o perfil de resistência, tratamentos e evolução clínica de pacientes internados com TBMDR e TBXDR no período de 2000 a 2014 em um Hospital de Referência no Estado de São Paulo, Brasil. Os dados foram obtidos diretamente do prontuário de pacientes e do banco de dados do TBWEB, que são informações clínico-epidemiológicas, exames e de tratamento do Programa de Controle de Tuberculose do Estado de São Paulo analisados através de estatística descritiva. Foram internados 39 pacientes no período de estudo, 29 (74,3%) TBMDR e 10 (25,7%) de TBXDR. Entre os TBMDR a taxa de cura foi de 79,3% e o tempo médio de tratamento foi de 19,6 meses. E no grupo dos TBXDR, 80% evoluíram com cura e o tempo médio de tratamento foi de 25,9 meses. A taxa de cura encontrada foi maior que a descrita em outros estudos. A supervisão completa de todo o tratamento, a utilização das recomendações do MS e OMS, adicionadas a uma história minuciosa dos fármacos utilizados previamente e adequação... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Although the incidence of Tuberculosis (TB) has declined in recent years, there is a significant increase in cases of MDRTBD (multi-drug resistant) and XDRTB (extensively drug-resistant). The situation is a serious public health problem in the world and in Brazil, with a lower cure rate, worse prognosis and no proven treatment for contacts. The estimated global cure rate for MDRTB is 52% and for XDRTB, outcomes are even less favorable. In this sense, we sought to determine the resistance profile, treatments and clinical evolution of patients hospitalized with MDR-TB and MDR-TB between 2000 and 2014 at a Reference Hospital in the State of São Paulo, Brazil. Data were obtained directly from the patient records and the TBWEB database, which are clinicalepidemiological information, tests and treatment of the Tuberculosis Control Program of the State of São Paulo, analyzed through descriptive statistics. Thirty-nine patients were hospitalized in the study period, 29 (74.3%) MDRTB and 10 (25.7%) MDRTB. Among the MDRTB, the cure rate was 79.3% and the mean treatment time was 19.6 months. And in the XDRTB group, 80% progressed with healing and the mean treatment time was 25.9 months. The cure rate found was higher than that reported in other studies. Complete supervision of all treatment, use of MS and WHO recommendations, added to a thorough history of the drugs previously used and adequacy of the schedules with TS results may contribute... (Complete abstract click electronic access below) / Mestre Tuberculose. Mycobacterium tuberculosis. Farmacorresistência bacteriana. Doentes hospitalizados. Saúde pública. Drug Resistance, Bacterial

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