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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 201 to 210 of 385 (0.032 seconds)Spelling suggestions: "subject:"drugdesign"" "subject:"cagedesign""
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USING MOLECULAR SIMILARITY ANALYSIS FOR STRUCTURE-ACTIVITY RELATIONSHIP STUDIESFAN, WEIGUO 27 November 2012 (has links)
No description available.
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| 202 |
Derivation of Hydroquinone to Produce Selective, Oxidatively Activated Chemotherapeutic AgentsBell-Horwath, Tiffany R. 12 September 2014 (has links)
No description available.
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| 203 |
Derivation of Hydroquinone to Produce Selective, Oxidatively Activated Chemotherapeutic AgentsBell-Horwath, Tiffany R. 17 October 2014 (has links)
No description available.
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| 204 |
Structure-guided Synthesis and Evaluation of Non-nucleoside Reversible, Competitive Inhibitors of Human Ribonucleotide Reductase as Anti-proliferative AgentsHuff, Sarah 06 September 2017 (has links)
No description available.
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| 205 |
Structure-based Computer-aided Drug Design and Analyses against Disease Target: Cytokine IL-6/IL-6R/GP130 ComplexShi, Guqin January 2017 (has links)
No description available.
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| 206 |
Development of Selective Inhibitors against Enzymes Involved in the Aspartate Biosynthetic Pathway for Antifungal Drug DevelopmentDahal, Gopal Prasad January 2018 (has links)
No description available.
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| 207 |
Investigation and Characterisation of Protein-Ligand Interactions: SRA-Ribonucleic Acid Recognition and Anti-Microbial Drug DiscoveryDavis, Caroline M. 10 September 2015 (has links)
No description available.
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| 208 |
MOLECULAR AND MACRO-MOLECULAR CYCLIZATION: STRUCTURE BASED DRUG DESIGN OPPORTUNITIES FOR TWO LYASE ENZYMESVijayaraghavan, Jagamya 05 June 2017 (has links)
No description available.
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| 209 |
In silico approaches for studying transporter and receptor structure-activity relationshipsChang, Cheng 13 July 2005 (has links)
No description available.
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| 210 |
Synthesis of Substituted Pyrrolidines / Syntes av substituerade pyrrolidinerSjölin, Olof January 2016 (has links)
The task of medicinal chemists in a drug discoveryproject is to synthesize/design analogues to the screening hits, simultaneouslyincreasing target potency and optimizing the pharmacological properties. This requires a wide selection of moleculesto be synthesized, where both synthetic feasibility and price of startingmaterials are of great importance. In this work, a synthetic pathway from cheapand readily available starting materials to highly modifiable 2,4-disubstitutedpyrrolidines is demonstrated. Previously reported procedures to similarpyrrolidines use expensive catalysts, requires harsh conditions and requiresnon-commercially available starting materials. The suggested pathway herein has demonstrated great possibility forvariation in the 4-position, including fluoro, difluoro, nitrile and alcoholfunctional groups. There are several areas in which the synthesis can beimproved and expanded upon. Improvements can be made by optimizing thedescribed reaction conditions and further expansion of possible modificationsin both 2- and 4-position could be explored.
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