Transient pressures subsequent to simultaneous power failure at all pumps of a multistage pumping system are analysed. Distributing pumping stations along a pipeline, rather than placing all of the required pumps within one pumping station, significantly reduces transient pressure fluctuations within the system. A computer program using the FORTRAN language is developed to analyse multistage pumping systems, with appropriate surge controls, in the event of such a power failure. These surge controls consist of valves, vacuum breakers, air chambers and reservoirs; with other controls easily added as they develop. Boundary conditions determining system controls are not developed as a part of this thesis, but are described for completeness. By comparing the maximum and minimum transient pressures occurring within- single stage and multistage systems, the premise that multistage systems give significantly lower transient pressures than single stage systems is substantiated. This reduction in transient pressures allows for possible savings in costs, as pipe wall thicknesses and the size of large, expensive control structures may be reduced. Examples demonstrating the use of the program are included. / Applied Science, Faculty of / Civil Engineering, Department of / Graduate

Graduation date: 1995

Call number: LD2668 .T4 1986 J66 / Master of Science / Chemical Engineering

With the attempt to achieve the optimum in analysis and design, the technological global knowledge base grows more and more. Engineers all over the world continuously modify and innovate existing analysis methods and design procedures to perform the same task more efficiently and with better results. In the field of complex structural analysis many researchers pursue this challenging task. The complexity of a lattice type structure is caused by numerous parameters: the nonlinear member performance of the material, the statistical variation of member load capacities, the highly indeterminate structural composition, etc. In order to achieve a simulation approach which represents the real world problem more accurately, it is necessary to develop technologies which include these parameters in the analysis. One of the new technologies is the first order nonlinear analysis of lattice type structures including the after failure response of individual members. Such an analysis is able to predict the failure behavior of a structural system under ultimate loads more accurately than the traditionally used linear elastic analysis or a classical first order nonlinear analysis. It is an analysis procedure which can more accurately evaluate the limit-state of a structural system. The Probability Based Analysis (PBA) is a new technology. It provides the user with a tool to analyze structural systems based on statistical variations in member capacities. Current analysis techniques have shown that structural failure is sensitive to member capacity. The combination of probability based analysis and the limit-state analysis will give the engineer the capability to establish a failure load distribution based on the limit-state capacity of the structure. This failure load distribution which gives statistical properties such as mean and variance improves the engineering judgment. The mean shows the expected value or the mathematical expectation of the failure load. The variance is a tool to measure the variability of the failure load distribution. Based on a certain load case, a small variance will indicate that a few members cause the tower failure over and over again; the design is unbalanced. A large variance will indicate that many different members caused the tower failure. The failure load distribution helps in comparing and evaluating actual test results versus analytical results by locating an actual test among the possible failure loads of a tower series. Additionally, the failure load distribution allows the engineer to calculate exclusion limits which are a measure of the probability of success, or conversely the probability of failure for a given load condition. The exclusion limit allows engineers to redefine their judgement on safety and usability of transmission towers. Existing transmission towers can be reanalyzed using this PBA and upgraded based on a given exclusion limit for a chosen tower capacity increase according to the elastic analysis from which the tower was designed. New transmission towers can be analyzed based on the actual yield strength data and their nonlinear member performances. Based on this innovative analysis the engineer is able to improve tower design by using a tool which represents the real world behavior of steel transmission towers more accurately. Consequently it will improve structural safety and reduce cost.

In an effort to minimize the harmful effects of intracellular ice formation (IIF) during cryopreservation of confluent tissues, computer simulations based on Monte Carlo methods were performed to predict the probability of IIF in confluent monolayers during various freezing procedures. To overcome the prohibitive computational costs of such simulations for large tissues, the well-known Johnson-Mehl-Avrami (JMA) model of crystallization kinetics was implemented as a continuum approximation of IIF in tissues. This model, which describes nucleation, growth, and impingement of crystals in a supercooled melt, is analogous to the process of intracellular ice formation and propagation in biological tissues. Based on the work of Weinberg and Kapral (1989), the JMA model was modified to account for finite-size effects, and was shown to predict accurately the results of freezing simulations in 1-D tissue constructs, for various propagation rates and tissue sizes. An initial analysis of IIF kinetics in 2-D tissues is also presented. The probability of IIF in 2-D liver tissue was measured experimentally during freezing of HepG2 cells cultured in monolayers, and compared to Monte Carlo simulations and predictions of the continuum model. The Avrami coefficient and exponent for IIF in HepG2 tissue were estimated to be k = 0.19 and n = 0.45.