- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 171 to 180 of 3735 (0.056 seconds)Spelling suggestions: "subject:"E. cold""
| 171 |
The pathogenicity of Escherichia coli on relation to antibodies and other drugsButler, M. D. January 1987 (has links)
No description available.
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| 172 |
The establishment of clostridial plasmid and chromosomal DNA in Escherichia coli and Bacillus subtilisCollins, M. E. January 1984 (has links)
No description available.
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| 173 |
Amplification of an IS1-flanked unit in Escherichia coli K12Clugston, C. K. January 1986 (has links)
No description available.
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| 174 |
Control of isocitrate dehydrogenase in Escherichia coli strain ML308Borthwick, Andrew Cullen January 1984 (has links)
No description available.
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| 175 |
Translocation and cytotoxicity of the HNH endonuclease colicin E9Walker, David Colin January 2001 (has links)
No description available.
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| 176 |
The role of the #beta# subunit of E. coli DNA-dependant RNA polymerase in stringent controlJones, Steven Tarran January 1988 (has links)
No description available.
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| 177 |
Computational studies of bacterial iron transport proteins : methodological aspects and applicationFaraldo-GoÌmez, JoseÌ D. January 2002 (has links)
No description available.
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| 178 |
The effect of accessory factors on the order of strand exchange during Xer recombinationBregu, Migena January 2002 (has links)
No description available.
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| 179 |
The chemotaxis genes of Rhodobacter sphaeroidesHamblin, Paul Andrew January 1997 (has links)
No description available.
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| 180 |
The analysis of methylglyoxal detoxification and stress responses in Escherichia coliOzyamak, Ertan January 2009 (has links)
Bacteria live in frequently changing environments and have to deal with a multitude of challenges. The chemical challenges to be faced are not only of exogenous origin, but can be the product of the metabolism, as in the case of methylglyoxal (MG), an endogenous electrophile that kills via damage to macromolecules. Escherichia coli (E. coli) has evolved sophisticated protective mechanisms to counteract the toxicity of MG. The glutathione-dependent glyoxalase system, consisting of glyoxalase I and II (GlxI & II), provides the main route for MG detoxification. Protection from MG is highly dependent on the activity of the KefB and KefC protein. KefB and KefC are homologous ligand-gated potassium efflux systems and are maintained inactive by the binding of glutathione, and are activated during MG detoxification by a specific intermediate molecule of the detoxification pathway, S-lactoylglutathione (SLG). The activity of these systems ultimately modulates the cytoplasmic pH. This study assessed the molecular and physiological role of the GlxII-encoding gene (gloB) in E. coli during MG stress. The study emphasises that the degree of KefB and KefC activation is affected by the relative specific activities of GlxI and GlxII via their impact on the SLG molecule. The significance of other genes in protection was poorly understood and this study allowed first insights into the transcriptional response of E. coli to MG stress. ChIPchip studies investigated the genome-wide RNA polymerase distribution of E. coli in response to MG. Furthermore, the contribution of the potassium efflux systems on transcriptional changes was assessed. The data show that E. coli invokes an adaptive transcriptional response that excludes the known key systems for cell survival. The data point to possible novel roles for several other mechanisms known to be involved for example aldehyde detoxification, potassium homeostasis and DNA damage repair.
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