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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 51 to 60 of 981 (0.028 seconds)Spelling suggestions: "subject:"elegans"" "subject:"celegans""
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Evaluation of virulence in wild type and pyrimidine auxotrophs of Pseudomonas aeruginosa using the eukaryotic model system Caenorhabditis elegans.Anvari, Sara 08 1900 (has links)
The human opportunistic pathogen, Pseudomonas aeruginosa PAO1, has been shown to kill the nematode Caenorhabditis elegans. C. elegans has been a valuable model for the study of bacterial pathogenesis, and has reinforced the notion that common virulence and host defense mechanisms exist. Recently, the pyrimidine pathway was shown to regulate virulence levels. Therefore, mutations in the pyrimidine pathway of PAO1 showed decrease virulence in the nematode. When starving the nematode, bacterial resistance was also shown to increase. It was hypothesized that starvation induced the DAF pathway, which regulates the transcription of genes involved with the antibacterial defense mechanism. Further research will be conducted to test this theory by performing RNAi experiments for the genes functioning in the antibacterial defense mechanism.
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Identification and molecular genetic characterization of a coq-4 knockout mutation in Caenorhabditis elegansHan, Dong, 1970- January 2001 (has links)
No description available.
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| 53 |
Genes that affect development and biological timing in Caenorhabditis elegansMeng, Yan, 1972- January 2000 (has links)
No description available.
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| 54 |
Genetic factors affecting life span in the nematode Caenorhabditis elegansLakowski, Bernard C. January 1998 (has links)
No description available.
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Role of cki-2 during development in C. elegansKim, Dae Young, 1968- January 2007 (has links)
No description available.
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| 56 |
Phenotypic consequences of altering expression of the Caenorhabditis elegans timing gene clk-1.Felkai, Stephanie. January 1998 (has links)
No description available.
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| 57 |
Genetic analysis of reversal behavior in C. elegansZhao, Beibei January 2003 (has links)
No description available.
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| 58 |
Identification of a protein that interacts with Caenorhadbitis elegans CLK-2 in a yeast two-hybrid assayWang, Ying January 2003 (has links)
No description available.
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The Caenorhabditis elegans Clock gene gro-1 encodes a metazoan N6-( [delta]2) isopentenyl PPi: tRNA isopentenyl transferase /Lemieux, Jason. January 1999 (has links)
No description available.
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| 60 |
Characterization of the C. elegans PLM Mechanosensory Neurons at the L1 larval stageYu, Fabian 29 October 2012 (has links)
Axon guidance is the developmental process where developing neurons navigate their processes based on attractive and repulsive cues. C. elegans has been an instrumental model in the study of neurobiology with one of the key benefits being a relatively simple nervous system which comprises of only 302 neurons. The Eph Receptors are a canonical class of axon guidance molecules and in C. elegans there is only Eph receptor VAB-1. To understand axon guidance it is useful to study the mechanosensory neurons, and in particular a pair of neurons called the PLM (Posterior Lateral Microtubule). In this thesis I undertook a series of projects involving new techniques, and identified gene products that may interact with VAB-1 in the PLMs. I demonstrate that the use of the PLM Length and PLM/Body length ratio at the L1 stage offers an improved way of detecting axon guidance phenotypes. I show proof of concept that use of a light induced cell ablation technique can help study the developing nervous system.
Further, I show that with the use of a tissue specific RNAi technique the role of lethal genes in axon guidance can be analyzed. Finally I conducted a screen that identified new effectors of the VAB-1 signal transduction pathway. / Thesis (Master, Biology) -- Queen's University, 2012-10-29 11:31:54.764
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