Spelling suggestions: "subject:"endothelial progenitor cells (EPC)"" "subject:"ndothelial progenitor cells (EPC)""
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The Use of Endothelial Progenitor Cells to Promote Bone Healing in a Defect Model in the Rat FemurAtesok, Kivanc 01 December 2011 (has links)
The objective of this project was to evaluate the effects of local endothelial progenitor cell (EPC) therapy on bone regeneration in a segmental defect in the rat femur. Animals from the EPC-treated (N=28) and control (N=28) groups were sacrificed at 1, 2, 3, and 10 weeks post-operatively. Bone healing was evaluated with radiographic, histological, and micro computed tomography (micro-CT) scans. Radiographically; mean scores of the EPC group at 1, 2, and 3 weeks were significantly higher compared to control group. At 10 weeks, all the animals in the EPC group had complete union (7/7), but in the control group none achieved union (0/7). Histologically, specimens from EPC-treated animals had abundant new bone formation compared to controls. Micro-CT assessment showed significantly improved parameters of bone healing for the EPC group compared to control group. In conclusion, local EPC therapy significantly enhanced bone regeneration in a segmental bone defect in rat femur.
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The Use of Endothelial Progenitor Cells to Promote Bone Healing in a Defect Model in the Rat FemurAtesok, Kivanc 01 December 2011 (has links)
The objective of this project was to evaluate the effects of local endothelial progenitor cell (EPC) therapy on bone regeneration in a segmental defect in the rat femur. Animals from the EPC-treated (N=28) and control (N=28) groups were sacrificed at 1, 2, 3, and 10 weeks post-operatively. Bone healing was evaluated with radiographic, histological, and micro computed tomography (micro-CT) scans. Radiographically; mean scores of the EPC group at 1, 2, and 3 weeks were significantly higher compared to control group. At 10 weeks, all the animals in the EPC group had complete union (7/7), but in the control group none achieved union (0/7). Histologically, specimens from EPC-treated animals had abundant new bone formation compared to controls. Micro-CT assessment showed significantly improved parameters of bone healing for the EPC group compared to control group. In conclusion, local EPC therapy significantly enhanced bone regeneration in a segmental bone defect in rat femur.
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Der Einfluss von Tabakentwöhnung auf die funktionellen Eigenschaften von endothelialen Progenitorzellen. / Effect of smoking cessation on the functional properties of endothelial progenitor cellsImmer, Lena 18 April 2012 (has links)
No description available.
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