ITC/USA 2007 Conference Proceedings / The Forty-Third Annual International Telemetering Conference and Technical Exhibition / October 22-25, 2007 / Riviera Hotel & Convention Center, Las Vegas, Nevada / Historically, different aspects of the configuration of an airborne instrumentation system were specified in a variety of different software applications. Instrumentation setup software handled the definition of measurements and PCM Formats while separate applications handled pre-flight checkout, calibration and post-flight data analysis. This led to the manual entry of the same data multiple times. Industry standards such as TMATS strive to address this problem by creating a data-interchange format for passing setup information from one application to another. However, a better alternative is to input all of the relevant setup information about the sensor and the measurement when it is initially created in the instrumentation vendor’s software. Furthermore, an additional performance enhancement can be achieved by adding the ability to perform sensor calibration and engineering unit conversions to pre-flight data visualization software that is tightly coupled with the instrumentation setup software. All of the setup information can then be transferred to the ground station for post-flight processing and data reduction. Detailed reports can also be generated for each measurement. This paper describes the flow of data through an integrated airborne instrumentation setup application that allows sensors and measurements to be defined, acquired, calibrated and converted from raw counts to engineering units. The process of performing a sensor calibration, configuring engineering unit conversions, and importing calibration and transducer data sheets will also be discussed.