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Epithelial cells: an immune modulator in the context of inflammatory bowel diseasesBacker, Jody Lynn 11 1900 (has links)
Inflammatory Bowel Diseases (IBD) result from the nexus of a genetic predisposition, dysregulated immunologic insult against commensal microflora, and an environmental trigger. The intestinal epithelium is a single cell layer that separates a highly active mucosal immune system from a large antigenic load in the intestinal lumen. Innate immune recognition combined with a highly regulated adaptive immune response maintains this tolerance. The intestinal epithelium in collusion with antigen presenting cells primarily modulates this activity. In this thesis, we show that, in response to DNA isolated from bacteria, innate toll like receptor 9 (TLR9) activation in intestinal epithelial cells modulates both arms of the immune system, to regulate intestinal homeostasis, and through this mechanism, Bifidobacteria breve DNA exerts its anti-inflammatory function. / Experimental Medicine
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The characterization of the induction of lipocortin I by administration of dexamethasone and thyroid hormone in a thymic epithelial cell lneRiley, Henry Drinker January 1990 (has links)
Thesis (Ph. D.)--University of Hawaii at Manoa, 1990. / Includes bibliographical references (leaves 68-76) / Microfiche. / xi, 76 leaves, bound ill. 29 cm
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The role of surfactant in, and a comparison of, the permeability of porcine and human epithelia to various chemical compounds /Viljoen, Ianda. January 2005 (has links)
Thesis (MScMed)--University of Stellenbosch, 2005. / Bibliography. Also available via the Internet.
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The role of Id-1 on the proliferation, motility and mitotic regulation of prostate epithelial cells /Di, Kaijun. January 2007 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2007. / Also available online.
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Alcohol and inflammation : a study of effects of ethanol on endothelial and epithelial cell functions /Johansson, Anne-Sofie, January 2007 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 5 uppsatser.
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Studies on mesothelial differentiation : prognostic and therapeutic approaches to malignant mesothelioma /Sun, Xiaojuan, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 5 uppsatser.
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Perturbation of the epithelial barrier by enteric pathogens /Tafazoli, Farideh, January 2001 (has links) (PDF)
Diss. (sammanfattning) Linköping : Univ., 2001. / Härtill 4 uppsatser.
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Aldehyde toxicity in human oral epithelium /Nilsson, Jan Anders, January 2004 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.
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Mechanisms of liver allograft rejections /Ge, Xupeng, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 4 uppsatser.
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Role of second messengers in controlling growth patterns of corneal epithelial cells /Liu, Ke. January 2002 (has links)
Thesis (Ph. D.)--University of Western Sydney, 2002. / "This thesis is submitted in fulfilment of the requirements of the degree of Doctor of Philosophy to the University of Western Sydney School of Biological Sciences."t.p. Includes bibliographical references (leaves 138-150).
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