- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 11 to 20 of 274 (0.024 seconds)Spelling suggestions: "subject:"eukaryotic"" "subject:"eukaryotics""
| 11 |
Replication and regulation of the 2 micron plasmid of yeastYull, Fiona Elizabeth January 1989 (has links)
No description available.
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| 12 |
Studies on replication origins in Saccharomyces cerevisiaeKipling, D. G. January 1989 (has links)
No description available.
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| 13 |
Responses to a site-specific DNA double-stranded break in Schizosaccharomyces pombePrudden, Giulia January 2002 (has links)
No description available.
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| 14 |
A molecular biological study of protein disulphide isomeraseMurant, Susan J. January 1989 (has links)
No description available.
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| 15 |
Post-translational modifications of #alpha#-tubulin in Trypanosoma brucei and Physarum polycephalumSasse, Rosemary January 1989 (has links)
No description available.
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| 16 |
Characterisation of the domain in Sla1p required for regulation of the yeast actin cytoskeletonDewar, Hilary January 2002 (has links)
No description available.
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| 17 |
Expression signals in retro-elementsRathjen, Peter David January 1988 (has links)
No description available.
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| 18 |
3' end formation of yeast and mammalian transcripts produced by RNA polymerase IIHumphrey, Timothy C. January 1991 (has links)
No description available.
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| 19 |
Localizing RNA polymerase subunits in human cellsJones, Emma January 1998 (has links)
No description available.
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| 20 |
Computational design of orthogonal microRNAs for synthetic biologyTrybilo, Maciej January 2013 (has links)
Upcoming applications of synthetic biology will require access to a wide array of robust genetic components (parts). The logic of a genetic system is encoded with regulatory elements such as pairs of transcription factors:promoters, miRNAs:target sites, or ribozymes:aptamers among others. Due to a relatively simple form and mode of operation of miRNAs, it is possible to design their synthetic variants. Out of all possible miRNA sequences the ones chosen should perform efficiently and should avoid cross-talk with both the host system circuits and within the imported synthetic ones. In this work, a computational method involving a series of heuristics is developed that can be used to design ensembles of such sequences depending on the host transcriptome. As an example, an ensemble of eight such miRNA sequences is produced using this method for use in a human host. Those have then been validated experimentally against the above-mentioned requirements by transfection into HEK 293 cells and flow cytometry measurements of fluorescent markers. The produced sequences are available for use from pENTR vectors of the Gateway cloning system. The required computations were facilitated by a modern cluster computing system—Kaichu—especially developed for this project, but fit for general purpose use and available under an open-source license.
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